PMID- 33520828
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220420
IS  - 2251-6581 (Print)
IS  - 2251-6581 (Electronic)
IS  - 2251-6581 (Linking)
VI  - 19
IP  - 2
DP  - 2020 Dec
TI  - Medication non-adherence in patients with type 2 diabetes mellitus with full 
      access to medicines.
PG  - 1105-1113
LID - 10.1007/s40200-020-00612-2 [doi]
AB  - PURPOSE: The pharmacological treatment for Type 2 diabetes mellitus (T2DM) is 
      continuous and adherence to medication is critical for disease control. 
      Restricted access to medicines is one of the most important barriers to adherence 
      to T2DM treatment. This study aimed to evaluate other factors for medication 
      non-adherence by studying patients with full access to oral hypoglycemic agents. 
      METHODS: Cross-sectional study with 300 patients receiving their medication 
      without costs from a referral center for diabetes care in Crato, Ceara (Brazil). 
      Participants were recruited from January to December 2017. Information was 
      obtained by self-applied questionnaires, and the drugs used were confirmed in the 
      prescription. Adherence to medication was determined by the Morisky Medication 
      Adherence Scale (MMAS-4). Patient perceptions of drugs were assessed by the 
      Beliefs about Medicines Questionnaire (BMQ). RESULTS: Only 22.7% of participants 
      met the criterion of high adherence to medication. The most frequent 
      characteristics in the low adherence group were married; hypertension; no regular 
      physical activity; therapy based on the combination of two or more oral 
      antidiabetic agents without insulin; low score in the BMQ necessity scale. 
      Necessity score in BMQ increased with age and the number of medications used and 
      decreased if the patient had family members with the same disease and had 
      children. CONCLUSIONS: Full access to medicines did not assure high adherence to 
      pharmacological treatment of type 2 diabetes mellitus. Distinctive factors to 
      medication non-adherence may be found and specific barriers should be considered 
      when planning actions for improving adherence in such populations.
CI  - (c) Springer Nature Switzerland AG 2020.
FAU - Saraiva, Emanuela Machado Silva
AU  - Saraiva EMS
AD  - Faculdade de Juazeiro do Norte (FJN), Juazeiro do Norte, Ceara Brazil.
AD  - Centro Universitario Saude ABC (CUSABC), Av Principe de Gales 821, Santo Andre, 
      Sao Paulo CEP 09060 - 650 Brazil. GRID: grid.419034.b. ISNI: 0000 0004 0413 8963
FAU - Coelho, Jose Leonardo Gomes
AU  - Coelho JLG
AD  - Faculdade de Juazeiro do Norte (FJN), Juazeiro do Norte, Ceara Brazil.
FAU - Dos Santos Figueiredo, Francisco Winter
AU  - Dos Santos Figueiredo FW
AUID- ORCID: 0000-0002-9377-6443
AD  - Centro Universitario Saude ABC (CUSABC), Av Principe de Gales 821, Santo Andre, 
      Sao Paulo CEP 09060 - 650 Brazil. GRID: grid.419034.b. ISNI: 0000 0004 0413 8963
FAU - do Souto, Ricardo Peres
AU  - do Souto RP
AUID- ORCID: 0000-0002-6281-5956
AD  - Centro Universitario Saude ABC (CUSABC), Av Principe de Gales 821, Santo Andre, 
      Sao Paulo CEP 09060 - 650 Brazil. GRID: grid.419034.b. ISNI: 0000 0004 0413 8963
LA  - eng
PT  - Journal Article
DEP - 20200813
PL  - Switzerland
TA  - J Diabetes Metab Disord
JT  - Journal of diabetes and metabolic disorders
JID - 101590741
PMC - PMC7843744
OTO - NOTNLM
OT  - Diabetes mellitus, type 2
OT  - Medication adherence
OT  - Oral hypoglycemic agents
OT  - Primary health care
COIS- Conflicts of interestThe authors declare no conflict of interest in this study.
EDAT- 2021/02/02 06:00
MHDA- 2021/02/02 06:01
PMCR- 2021/08/13
CRDT- 2021/02/01 05:59
PHST- 2020/02/12 00:00 [received]
PHST- 2020/07/23 00:00 [revised]
PHST- 2020/08/10 00:00 [accepted]
PHST- 2021/02/01 05:59 [entrez]
PHST- 2021/02/02 06:00 [pubmed]
PHST- 2021/02/02 06:01 [medline]
PHST- 2021/08/13 00:00 [pmc-release]
AID - 612 [pii]
AID - 10.1007/s40200-020-00612-2 [doi]
PST - epublish
SO  - J Diabetes Metab Disord. 2020 Aug 13;19(2):1105-1113. doi: 
      10.1007/s40200-020-00612-2. eCollection 2020 Dec.