PMID- 33526270
OWN - NLM
STAT- MEDLINE
DCOM- 20211012
LR  - 20211012
IS  - 1532-818X (Electronic)
IS  - 0196-0709 (Linking)
VI  - 42
IP  - 3
DP  - 2021 May-Jun
TI  - Sarcomatoid larynx carcinoma differential clinical evolution, on field 
      statistical considerations.
PG  - 102934
LID - S0196-0709(21)00035-1 [pii]
LID - 10.1016/j.amjoto.2021.102934 [doi]
AB  - Spindle cell larynx carcinoma (SpCC) represents around 3% of laryngeal cancers. 
      It is originated by a single cancer stem cell undergoing epithelial to 
      mesenchymal transition. This explains the aggressiveness, the peculiar resistance 
      to conventional therapy and the frequent relapses. We focused on this particular 
      cancer subset characteristics in patients, in early and advanced stages primarily 
      aiming to define and highlight the differences with Laryngeal Squamous Cell 
      Carcinoma (LSCC) focusing on clinical features, treatments, follow-up and 
      survival in a patient's cohort composed by comparable cases from two subgroups.
CI  - Copyright (c) 2021. Published by Elsevier Inc.
FAU - Ricciardiello, Filippo
AU  - Ricciardiello F
AD  - Ear, Nose, and Throat Unit, AORN "Antonio Cardarelli", Naples, Italy. Electronic 
      address: filipporicciardiello@virgilio.it.
FAU - Bocchetti, Marco
AU  - Bocchetti M
AD  - Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 
      Naples, Italy; Biogem Scarl, Molecular Oncology and Precision Medicine 
      Laboratory, Via Camporeale, 83031 Ariano Irpino, Italy.
FAU - Pellini, Raul
AU  - Pellini R
AD  - Department of Otolaryngology-Head and Neck Surgery, IRCCS Regina Elena National 
      Cancer Institute, Rome, Italy.
FAU - Palladino, Remo
AU  - Palladino R
AD  - Otolaryngology, P.O. Umberto I, Nocera Inferiore, Salerno, Italy.
FAU - Caraglia, Michele
AU  - Caraglia M
AD  - Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 
      Naples, Italy; Biogem Scarl, Molecular Oncology and Precision Medicine 
      Laboratory, Via Camporeale, 83031 Ariano Irpino, Italy.
FAU - Boscaino, Amedeo
AU  - Boscaino A
AD  - U.O.C. Pathology Unit, AORN "Antonio Cardarelli", Naples, Italy.
FAU - Petruzzi, Gerardo
AU  - Petruzzi G
AD  - Department of Otolaryngology-Head and Neck Surgery, IRCCS Regina Elena National 
      Cancer Institute, Rome, Italy.
FAU - Romano, Francesco Jacopo
AU  - Romano FJ
AD  - U.O.C. Oncology Unit, AORN "Antonio Cardarelli", Naples, Italy.
FAU - Chiurazzi, Bruno
AU  - Chiurazzi B
AD  - U.O.C. Oncology Unit, AORN "Antonio Cardarelli", Naples, Italy.
FAU - Addeo, Raffaele
AU  - Addeo R
AD  - Oncology Unit, Day Hospital, San Giovanni di Dio Hospital, ASL Napoles 2 Nord, 
      Frattamaggiore, Italy.
FAU - Mazzone, Salvatore
AU  - Mazzone S
AD  - Ear, Nose, and Throat Unit, AORN "Antonio Cardarelli", Naples, Italy.
FAU - Mesolella, Massimo
AU  - Mesolella M
AD  - Department of Neuroscience, Reproductive and Odontostomatological Science, Ear 
      Nose and Throat Unit, University of Naples 'Federico II', Naples, Italy.
FAU - Oliva, Flavia
AU  - Oliva F
AD  - Ear, Nose, and Throat Unit, AORN "Antonio Cardarelli", Naples, Italy.
FAU - Iorio, Brigida
AU  - Iorio B
AD  - Department of Otolaryngology, Pellegrini Hospital, ASL Napoli 1 Centro, Naples, 
      Italy.
LA  - eng
PT  - Journal Article
DEP - 20210127
PL  - United States
TA  - Am J Otolaryngol
JT  - American journal of otolaryngology
JID - 8000029
RN  - 0 (Antineoplastic Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Antineoplastic Agents/pharmacology/therapeutic use
MH  - Carcinoma, Squamous Cell/mortality/pathology
MH  - Drug Resistance, Neoplasm
MH  - Female
MH  - Humans
MH  - Laryngeal Neoplasms/mortality/*pathology/therapy
MH  - Male
MH  - Middle Aged
MH  - Neoplasm Recurrence, Local
MH  - Neoplasm Staging
MH  - Sarcoma/mortality/*pathology/therapy
MH  - Survival Rate
OTO - NOTNLM
OT  - Larynx
OT  - Spidle cell carcinoma
OT  - Squamous cell carcinoma
OT  - Statistical analysis
OT  - Survival
EDAT- 2021/02/03 06:00
MHDA- 2021/10/13 06:00
CRDT- 2021/02/02 05:48
PHST- 2020/12/14 00:00 [received]
PHST- 2021/01/13 00:00 [revised]
PHST- 2021/01/14 00:00 [accepted]
PHST- 2021/02/03 06:00 [pubmed]
PHST- 2021/10/13 06:00 [medline]
PHST- 2021/02/02 05:48 [entrez]
AID - S0196-0709(21)00035-1 [pii]
AID - 10.1016/j.amjoto.2021.102934 [doi]
PST - ppublish
SO  - Am J Otolaryngol. 2021 May-Jun;42(3):102934. doi: 10.1016/j.amjoto.2021.102934. 
      Epub 2021 Jan 27.