PMID- 33530171
OWN - NLM
STAT- MEDLINE
DCOM- 20210208
LR  - 20230103
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 100
IP  - 4
DP  - 2021 Jan 29
TI  - Efficacy and safety of ligation of intersphincteric fistula tract in the 
      treatment of anal fistula: A protocol for systematic review and meta-analysis.
PG  - e23700
LID - 10.1097/MD.0000000000023700 [doi]
LID - e23700
AB  - BACKGROUND: Anal fistula is characterized with perianal cellulitis, anorectal 
      pain, smelly or bloody drainage of pus, and difficulty in controlling bowel 
      movements. Ligation of intersphincteric fistula tract (LIFT) technique is a 
      recently developed approach against anal fistula, and it could alleviate the pain 
      of the patient, with little postoperative trauma, which can greatly shorten the 
      wound healing time and hospitalization stay. We conduct the meta-analysis and 
      systematic review to systematically evaluate the clinical efficacy and safety of 
      LIFT in the treatment of anal fistula. METHODS: Randomized controlled trials of 
      LIFT against anal fistula will be searched in several Chinese and English 
      databases. Two reviewers will independently conduct the literature extraction and 
      risk of bias assessment. Statistical analysis will be conducted in RevMan 5.3. 
      RESULTS AND CONCLUSIONS: The study will help to systematically evaluate the 
      clinical efficacy and safety of LIFT in the treatment of anal fistula. OSF 
      REGISTRATION NUMBER: DOI 10.17605/OSF.IO/T4FUH.
CI  - Copyright (c) 2021 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Zhang, Jiaji
AU  - Zhang J
AUID- ORCID: 0000-0003-2726-6290
AD  - Air Force Hospital of Eastern Theater Command, Nanjing, Jiangsu province, China.
FAU - Hao, Xilu
AU  - Hao X
FAU - Zhu, Yican
AU  - Zhu Y
FAU - Luan, Ronggang
AU  - Luan R
LA  - eng
GR  - No.201603005/the Nanjing Medical Science and technology development project/
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Anal Canal/*surgery
MH  - Humans
MH  - Length of Stay
MH  - Ligation/*methods
MH  - Meta-Analysis as Topic
MH  - Randomized Controlled Trials as Topic
MH  - Rectal Fistula/*surgery
MH  - Research Design
MH  - Systematic Reviews as Topic
MH  - Treatment Outcome
MH  - Wound Healing
PMC - PMC7850721
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2021/02/04 06:00
MHDA- 2021/02/09 06:00
PMCR- 2021/01/29
CRDT- 2021/02/03 01:00
PHST- 2020/11/11 00:00 [received]
PHST- 2020/11/16 00:00 [accepted]
PHST- 2021/02/03 01:00 [entrez]
PHST- 2021/02/04 06:00 [pubmed]
PHST- 2021/02/09 06:00 [medline]
PHST- 2021/01/29 00:00 [pmc-release]
AID - 00005792-202101290-00021 [pii]
AID - MD-D-20-11134 [pii]
AID - 10.1097/MD.0000000000023700 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2021 Jan 29;100(4):e23700. doi: 
      10.1097/MD.0000000000023700.