PMID- 33530870 OWN - NLM STAT- MEDLINE DCOM- 20210624 LR - 20220423 IS - 0260-1060 (Print) IS - 0260-1060 (Linking) VI - 27 IP - 2 DP - 2021 Jun TI - Dietary magnesium intake in relation to body mass index and glycemic indices in middle school students from the HEALTHY Study. PG - 211-219 LID - 10.1177/0260106020982345 [doi] AB - BACKGROUND: Data on dietary magnesium intake on the risk of type 2 diabetes mellitus (T2DM) among children and adolescents is limited. AIM: We examined whether dietary magnesium intake was related to body mass index (BMI) percentile, and glycemic indices at baseline and at end of the HEALTHY Study for both intervention and control schools. The HEALTHY Study was a multi-component, school-based intervention, to prevent T2DM in children and adolescents from 6th to 8th grades. METHODS: A secondary data analyses of 2181 ethnically diverse students with completed dietary records, BMI percentile, and plasma insulin and glucose concentrations at baseline (6th grade) and end of study (8th grade) were included from the HEALTHY Study. Dietary magnesium intake was self-reported using the Block Kids Food Frequency Questionnaire. A hierarchical multiple regression model was used to determine the relationships between dietary magnesium intake, BMI percentile, and glycemic indices at baseline and end of the HEALTHY Study, adjusting for magnesium intake from supplements, total energy intake, and fitness level. RESULTS: Dietary magnesium intake was related to BMI percentile at baseline and at end of the HEATHY Study (beta = -0.05, 95% CI = -0.02 to 0, p = 0.04; beta = -0.06, 95% CI = -0.02 to -0.003, p = 0.004); R (2) [regression coefficient effect size] = 0.03; R (2) = 0.06). Dietary magnesium intake was not related to plasma insulin and glucose concentrations at baseline and end of the HEALTHY Study. CONCLUSION: Dietary magnesium intake was inversely related to BMI percentile among middle school students from the HEALTHY Study. Research is required to evaluate the dose-response relationship between fruit and vegetable consumption (good sources of magnesium) and risk of T2DM in children and adolescents. This relationship also needs to be explored among different BMI categories. FAU - Naseeb, Manal AU - Naseeb M AUID- ORCID: 0000-0002-6851-5276 AD - Clinical Nutrition Department, 6527Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia. FAU - Milliron, Brandy-Joe AU - Milliron BJ AUID- ORCID: 0000-0003-1113-9043 AD - Department of Nutrition Sciences, 6527Drexel University, Philadelphia, PA, USA. FAU - Bruneau, Michael L Jr AU - Bruneau ML Jr AD - Department of Health Sciences, 6527Drexel University, Philadelphia, PA, USA. FAU - Sukumar, Deeptha AU - Sukumar D AD - Department of Nutrition Sciences, 6527Drexel University, Philadelphia, PA, USA. FAU - Foster, Gary D AU - Foster GD AD - WW International, New York, NY, USA. FAU - Smith, Sinclair A AU - Smith SA AD - Department of Health Sciences, 6527Drexel University, Philadelphia, PA, USA. FAU - Volpe, Stella L AU - Volpe SL AUID- ORCID: 0000-0002-8593-320X AD - 1757Virginia Polytechnic Institute and State University, Blacksburg, VA, USA. LA - eng PT - Journal Article DEP - 20210202 PL - England TA - Nutr Health JT - Nutrition and health JID - 8306569 RN - I38ZP9992A (Magnesium) SB - IM MH - Adolescent MH - Body Mass Index MH - Child MH - *Diabetes Mellitus, Type 2/epidemiology/prevention & control MH - Glycemic Index MH - Humans MH - *Magnesium MH - Schools MH - Students OTO - NOTNLM OT - HEALTHY study OT - Type 2 diabetes mellitus OT - body mass index OT - children and adolescents OT - dietary magnesium OT - fasting plasma glucose concentrations OT - fasting plasma insulin concentrations EDAT- 2021/02/04 06:00 MHDA- 2021/06/25 06:00 CRDT- 2021/02/03 05:35 PHST- 2021/02/04 06:00 [pubmed] PHST- 2021/06/25 06:00 [medline] PHST- 2021/02/03 05:35 [entrez] AID - 10.1177/0260106020982345 [doi] PST - ppublish SO - Nutr Health. 2021 Jun;27(2):211-219. doi: 10.1177/0260106020982345. Epub 2021 Feb 2.