PMID- 33541820 OWN - NLM STAT- MEDLINE DCOM- 20210929 LR - 20210929 IS - 1444-2892 (Electronic) IS - 1443-9506 (Linking) VI - 30 IP - 6 DP - 2021 Jun TI - Biomedical, Socioeconomic and Demographic Predictors of Heart Failure Readmissions: A Systematic Review. PG - 817-836 LID - S1443-9506(20)31556-0 [pii] LID - 10.1016/j.hlc.2020.11.011 [doi] AB - AIMS: To identify the biomedical, socioeconomic and demographic predictors of heart failure (HF) related readmissions in adult patients with HF. METHODS: This systematic review was conducted in March 2020 using the databases EMBASE, CINAHL and Medline to identify publications between 2015-2020. The resulting articles were systematically reviewed according to the PRISMA guidelines. RESULTS: Eighteen (18) studies were included in this review. Unemployment (HR=1.09; 95%CI=1.05-1.14; p=0.03) was the only socioeconomic factor predictive of HF-readmissions. Socio-Economic Indexes for Areas (SEIFA) scores did not predict HF readmissions in adults with HF (p>0.05). All patients included in the studies had pre-existing HF. Based on the included studies, Indigenous status was identified as a risk factor for HF readmissions in 1 study (p<0.05), and age or sex did not affect HF readmission patterns (p>0.05). New York Heart Association (NYHA) class, brain natriuretic peptide (BNP) levels, and heart rate were also predictive of HF readmission (p<0.05). Left ventricular ejection fraction and blood pressure, however, were non-significant risk factors of HF readmissions (p>0.05). CONCLUSIONS: This review identified unemployment, Indigenous status, NYHA class, heart rate, and BNP levels to predict HF related readmissions in adult patients with HF. Adding demographic and socioeconomic variables to readmission risk models has the potential to more accurately target patients at risk of readmissions. CI - Copyright (c) 2020 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved. FAU - Choi, Eun Sun AU - Choi ES AD - University of Sydney, Faculty of Medicine & Health, Sydney, NSW, Australia. Electronic address: echo0132@uni.sydney.edu.au. FAU - Wiseman, Taneal AU - Wiseman T AD - University of Sydney, Faculty of Medicine & Health, Sydney, NSW, Australia. FAU - Betihavas, Vasiliki AU - Betihavas V AD - Australian Catholic University, Faculty of Health Sciences, Sydney, NSW, Australia. LA - eng PT - Journal Article PT - Review PT - Systematic Review DEP - 20210201 PL - Australia TA - Heart Lung Circ JT - Heart, lung & circulation JID - 100963739 SB - IM MH - Adult MH - Demography MH - *Heart Failure/diagnosis/epidemiology/therapy MH - Humans MH - *Patient Readmission MH - Socioeconomic Factors MH - Stroke Volume MH - Ventricular Function, Left OTO - NOTNLM OT - Biomedical research OT - Demography OT - Heart failure OT - Patient readmission OT - Socioeconomic factors EDAT- 2021/02/06 06:00 MHDA- 2021/09/30 06:00 CRDT- 2021/02/05 05:45 PHST- 2020/07/06 00:00 [received] PHST- 2020/10/30 00:00 [revised] PHST- 2020/11/22 00:00 [accepted] PHST- 2021/02/06 06:00 [pubmed] PHST- 2021/09/30 06:00 [medline] PHST- 2021/02/05 05:45 [entrez] AID - S1443-9506(20)31556-0 [pii] AID - 10.1016/j.hlc.2020.11.011 [doi] PST - ppublish SO - Heart Lung Circ. 2021 Jun;30(6):817-836. doi: 10.1016/j.hlc.2020.11.011. Epub 2021 Feb 1.