PMID- 33542029 OWN - NLM STAT- MEDLINE DCOM- 20211021 LR - 20211119 IS - 1470-2738 (Electronic) IS - 0143-005X (Print) IS - 0143-005X (Linking) VI - 75 IP - 9 DP - 2021 Sep TI - Association of education level with diabetes prevalence in Latin American cities and its modification by city social environment. PG - 874-880 LID - 10.1136/jech-2020-216116 [doi] AB - BACKGROUND: Diabetes prevalence continues to increase in urban areas of low-income and middle-income countries (LMIC). Evidence from high-income countries suggests an inverse association between educational attainment and diabetes, but research in LMIC is limited. We investigated educational differences in diabetes prevalence across 232 Latin American (LA) cities, and the extent to which these inequities vary across countries/cities and are modified by city socioeconomic factors. METHODS: Using harmonised health survey and census data for 110 498 city dwellers from eight LA countries, we estimated the association between education and diabetes. We considered effect modification by city Social Environment Index (SEI) as a proxy for city-level development using multilevel models, considering heterogeneity by sex and country. RESULTS: In women, there was an inverse dose-response relationship between education and diabetes (OR: 0.80 per level increase in education, 95% CI 0.75 to 0.85), consistent across countries and not modified by SEI. In men, Argentina, Brazil, Colombia, Chile and Mexico showed an inverse association (pooled OR: 0.92; 95% CI 0.86 to 0.99). Peru, Panama and El Salvador showed a positive relationship (pooled OR 1.24; 95% CI 1.04 to 1.49). For men, these associations were further modified by city-SEI: in countries with an inverse association, it became stronger as city-SEI increased. In countries where the association was positive, it became weaker as city-SEI increased. CONCLUSION: Social inequities in diabetes inequalities increase as cities develop. To achieve non-communicable disease-related sustainable development goals in LMIC, there is an urgent need to develop policies aimed at reducing these educational inequities. CI - (c) Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. FAU - Braverman-Bronstein, Ariela AU - Braverman-Bronstein A AUID- ORCID: 0000-0002-9999-808X AD - Urban Health Collaborative, Drexel University Dornsife School of Public Health, Philadelphia, PA, USA ab4257@drexel.edu. FAU - Hessel, Philipp AU - Hessel P AD - School of Government, Universidad de los Andes, Bogota, Colombia. FAU - Gonzalez-Uribe, Catalina AU - Gonzalez-Uribe C AD - School of Medicine, University of Los Andes, Bogota, Colombia. FAU - Kroker, Maria F AU - Kroker MF AD - INCAP Research Center for the Prevention of Chronic Diseases, Institute of Nutrition of Central America and Panama, Guatemala City, Guatemala. FAU - Diez-Canseco, Francisco AU - Diez-Canseco F AD - CRONICAS, Center of Excellence in Chronic Diseases, University Peruana Cayetano Heredia, Lima, Peru. FAU - Langellier, Brent AU - Langellier B AD - Urban Health Collaborative, Drexel University Dornsife School of Public Health, Philadelphia, PA, USA. FAU - Lucumi, Diego I AU - Lucumi DI AD - School of Government, Universidad de los Andes, Bogota, Colombia. FAU - Rodriguez Osiac, Lorena AU - Rodriguez Osiac L AD - School of Medicine, University of Chile, Santiago, Chile. FAU - Trotta, Andres AU - Trotta A AUID- ORCID: 0000-0003-4181-1494 AD - Institute of Collective Health, National University of Lanus, Buenos Aires, Argentina. FAU - Diez Roux, Ana V AU - Diez Roux AV AD - Urban Health Collaborative, Drexel University Dornsife School of Public Health, Philadelphia, PA, USA. LA - eng GR - WT_/Wellcome Trust/United Kingdom GR - 205177/WT_/Wellcome Trust/United Kingdom GR - 205177/Z/16/Z/WT_/Wellcome Trust/United Kingdom GR - P30 DK111022/DK/NIDDK NIH HHS/United States PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20210204 PL - England TA - J Epidemiol Community Health JT - Journal of epidemiology and community health JID - 7909766 SB - IM MH - Cities/epidemiology MH - *Diabetes Mellitus/epidemiology MH - Female MH - Humans MH - Latin America/epidemiology MH - Male MH - Prevalence MH - *Social Environment MH - Socioeconomic Factors PMC - PMC7611487 MID - EMS131090 OTO - NOTNLM OT - diabetes OT - education OT - epidemiology OT - social inequalities OT - urbanisation COIS- Competing interests: None declared. EDAT- 2021/02/06 06:00 MHDA- 2021/11/20 06:00 PMCR- 2021/08/18 CRDT- 2021/02/05 05:46 PHST- 2020/11/23 00:00 [received] PHST- 2021/01/14 00:00 [revised] PHST- 2021/01/23 00:00 [accepted] PHST- 2021/02/06 06:00 [pubmed] PHST- 2021/11/20 06:00 [medline] PHST- 2021/02/05 05:46 [entrez] PHST- 2021/08/18 00:00 [pmc-release] AID - jech-2020-216116 [pii] AID - 10.1136/jech-2020-216116 [doi] PST - ppublish SO - J Epidemiol Community Health. 2021 Sep;75(9):874-880. doi: 10.1136/jech-2020-216116. Epub 2021 Feb 4.