PMID- 33545965
OWN - NLM
STAT- MEDLINE
DCOM- 20210216
LR  - 20210216
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 100
IP  - 3
DP  - 2021 Jan 22
TI  - Magnifying endoscopy in detecting early gastric cancer: A network meta-analysis 
      of prospective studies.
PG  - e23934
LID - 10.1097/MD.0000000000023934 [doi]
LID - e23934
AB  - BACKGROUND: Conventional white-light imaging endoscopy (C-WLI) had a significant 
      number of misdiagnosis in early gastric cancer (EGC), and magnifying endoscopy 
      (ME) combined with different optical imaging was more accurate in the diagnosis 
      of EGC. This study aimed to evaluate the accuracy of ME and compare the accuracy 
      of ME with different optical imaging in detecting EGC. METHODS: A comprehensive 
      literature search was conducted to identify all relevant studies. Pair-wise 
      meta-analysis was conducted to evaluate the accuracy of ME, and Bayesian network 
      meta-analysis was performed to combine direct and indirect evidence and estimate 
      the relative effects. RESULTS: Eight prospective studies were identified with a 
      total of 5948 patients and 3 optical imaging in ME (ME with WLI (M-WLI), ME with 
      narrow-band imaging (M-NBI), and ME with blue laser imaging (M-BLI)). Pair-wise 
      meta-analysis showed a higher accuracy of ME than C-WLI (OR: 2.97, 95% CI: 
      1.68 approximately 5.25). In network meta-analysis, both M-NBI and M-BLI were more accurate 
      than M-WLI (OR: 2.56, 95% CI: 2.13 approximately 3.13; OR: 3.13, 95% CI: 1.85 approximately 5.71). There was 
      no significant difference between M-NBI and M-BLI. CONCLUSION: ME was effective 
      in improving the detecting rate of EGC, especially with NBI or BLI.
CI  - Copyright (c) 2021 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Le, Hao
AU  - Le H
AD  - First Department of Surgery.
FAU - Wang, Lianjun
AU  - Wang L
AD  - First Department of Surgery.
FAU - Zhang, Lan
AU  - Zhang L
AD  - First Department of Surgery.
FAU - Chen, Pengfei
AU  - Chen P
AD  - Department of Gastroenterology, The Central Hospital of Enshi Tujia And Miao 
      Autonomous Prefecture, Enshi.
FAU - Xu, Bin
AU  - Xu B
AD  - First Department of Surgery.
FAU - Peng, Dengfa
AU  - Peng D
AD  - First Department of Surgery.
FAU - Yang, Ming
AU  - Yang M
AD  - First Department of Surgery.
FAU - Tan, Yong
AU  - Tan Y
AD  - First Department of Surgery.
FAU - Cai, Changsong
AU  - Cai C
AD  - First Department of Surgery.
FAU - Li, Huqing
AU  - Li H
AD  - First Department of Surgery.
FAU - Zhao, Qiu
AU  - Zhao Q
AD  - Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Wuhan, 
      China.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Early Detection of Cancer/methods
MH  - Endoscopy/*methods/standards/statistics & numerical data
MH  - Humans
MH  - Network Meta-Analysis
MH  - Odds Ratio
MH  - Prospective Studies
MH  - Stomach Neoplasms/*diagnosis/physiopathology
PMC - PMC7837915
COIS- The authors have no funding and conflicts of interests to declare.
EDAT- 2021/02/07 06:00
MHDA- 2021/02/17 06:00
PMCR- 2021/01/22
CRDT- 2021/02/06 01:01
PHST- 2019/07/24 00:00 [received]
PHST- 2020/11/26 00:00 [accepted]
PHST- 2021/02/06 01:01 [entrez]
PHST- 2021/02/07 06:00 [pubmed]
PHST- 2021/02/17 06:00 [medline]
PHST- 2021/01/22 00:00 [pmc-release]
AID - 00005792-202101220-00045 [pii]
AID - MD-D-19-05847 [pii]
AID - 10.1097/MD.0000000000023934 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2021 Jan 22;100(3):e23934. doi: 
      10.1097/MD.0000000000023934.