PMID- 33549009 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20210514 IS - 2224-5839 (Electronic) IS - 2224-5820 (Linking) VI - 10 IP - 3 DP - 2021 Mar TI - The impact of metabolic syndrome on the safety and efficacy of flexible ureterorenoscopy. PG - 2776-2780 LID - 10.21037/apm-20-2143 [doi] AB - BACKGROUND: To analyze the impact of metabolic syndrome on the safety and efficacy of flexible ureterorenoscopy (fURS) in managing kidney calculi. METHODS: We retrospectively analyzed the records of 151 patients who received fURS for the renal stones in our center between January 2014 and December 2016. The patients were divided into two groups based on whether they were diagnosed with metabolic syndrome. Information related to the patients, stones and surgeries were analyzed, and the stone-free rates (SFRs) and complications after fURS were reviewed. RESULTS: Group 1 consisted of patients with metabolic syndrome, and group 2 contained patients without metabolic syndrome. The mean stone size was 71.9+/-58.3 mm2 in group 1 and 64.9+/-43.7 mm2 in group 2 (P=0.399). The mean hospitalization and surgical durations were similar between both groups (P>0.05). The overall complication rates were 8.3% vs. 12.1% (P=0.514). The SFR at 3 months postoperative in group 1 was significantly lower than that in group 2 (80% vs. 92.3%, P<0.05). CONCLUSIONS: Our study results revealed that patients with metabolic syndrome can be treated safely with fURS. however, metabolic syndrome has a negative impact on the efficacy of fURS in the treatment of patients with kidney stone. FAU - Liu, Jun AU - Liu J AD - Urology and lithotripsy center, Peking University People's Hospital, Beijing, China; Peking University applied lithotripsy institute, Beijing, China. FAU - Hong, Yang AU - Hong Y AD - Urology and lithotripsy center, Peking University People's Hospital, Beijing, China; Peking University applied lithotripsy institute, Beijing, China. FAU - Yang, Bo AU - Yang B AD - Urology and lithotripsy center, Peking University People's Hospital, Beijing, China; Peking University applied lithotripsy institute, Beijing, China. huang6299@sina.com. FAU - Huang, Xiaobo AU - Huang X AD - Urology and lithotripsy center, Peking University People's Hospital, Beijing, China; Peking University applied lithotripsy institute, Beijing, China. FAU - Xu, Qingquan AU - Xu Q AD - Urology and lithotripsy center, Peking University People's Hospital, Beijing, China; Peking University applied lithotripsy institute, Beijing, China. FAU - Xiong, Liulin AU - Xiong L AD - Urology and lithotripsy center, Peking University People's Hospital, Beijing, China; Peking University applied lithotripsy institute, Beijing, China. FAU - Wang, Xiaofeng AU - Wang X AD - Department of Urology, Peking University International Hospital, Beijing, China. LA - eng PT - Journal Article DEP - 20210128 PL - China TA - Ann Palliat Med JT - Annals of palliative medicine JID - 101585484 SB - IM MH - Humans MH - *Kidney Calculi/surgery MH - *Metabolic Syndrome MH - Retrospective Studies MH - Treatment Outcome MH - Ureteroscopy OTO - NOTNLM OT - Flexible ureterorenoscopy (fURS) OT - kidney stone OT - metabolic syndrome OT - stone-free rates (SFRs) EDAT- 2021/02/08 06:00 MHDA- 2021/05/15 06:00 CRDT- 2021/02/07 20:25 PHST- 2020/10/30 00:00 [received] PHST- 2020/12/08 00:00 [accepted] PHST- 2021/02/08 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] PHST- 2021/02/07 20:25 [entrez] AID - apm-20-2143 [pii] AID - 10.21037/apm-20-2143 [doi] PST - ppublish SO - Ann Palliat Med. 2021 Mar;10(3):2776-2780. doi: 10.21037/apm-20-2143. Epub 2021 Jan 28.