PMID- 33552457
OWN - NLM
STAT- MEDLINE
DCOM- 20210218
LR  - 20221207
IS  - 2040-2309 (Electronic)
IS  - 2040-2295 (Print)
IS  - 2040-2295 (Linking)
VI  - 2021
DP  - 2021
TI  - Comparative Evaluation of the Treatment of COVID-19 with Multicriteria 
      Decision-Making Techniques.
PG  - 8864522
LID - 10.1155/2021/8864522 [doi]
LID - 8864522
AB  - OBJECTIVES: The outbreak of coronavirus disease 2019 (COVID-19) was first 
      reported in December 2019. Until now, many drugs and methods have been used in 
      the treatment of the disease. However, no effective treatment option has been 
      found and only case-based successes have been achieved so far. This study aims to 
      evaluate COVID-19 treatment options using multicriteria decision-making (MCDM) 
      techniques. METHODS: In this study, we evaluated the available COVID-19 treatment 
      options by MCDM techniques, namely, fuzzy PROMETHEE and VIKOR. These techniques 
      are based on the evaluation and comparison of complex and multiple criteria to 
      evaluate the most appropriate alternative. We evaluated current treatment options 
      including favipiravir (FPV), lopinavir/ritonavir, hydroxychloroquine, 
      interleukin-1 blocker, intravenous immunoglobulin (IVIG), and plasma exchange. 
      The criteria used for the analysis include side effects, method of administration 
      of the drug, cost, turnover of plasma, level of fever, age, pregnancy, and kidney 
      function. RESULTS: The results showed that plasma exchange was the most preferred 
      alternative, followed by FPV and IVIG, while hydroxychloroquine was the least 
      favorable one. New alternatives could be considered once they are available, and 
      weights could be assigned based on the opinions of the decision-makers 
      (physicians/clinicians). The treatment methods that we evaluated with MCDM 
      methods will be beneficial for both healthcare users and to rapidly end the 
      global pandemic. The proposed method is applicable for analyzing the alternatives 
      to the selection problem with quantitative and qualitative data. In addition, it 
      allows the decision-maker to define the problem simply under uncertainty. 
      CONCLUSIONS: Fuzzy PROMETHEE and VIKOR techniques are applied in aiding 
      decision-makers in choosing the right treatment technique for the management of 
      COVID-19.
CI  - Copyright (c) 2021 Figen Sarigul Yildirim et al.
FAU - Yildirim, Figen Sarigul
AU  - Yildirim FS
AUID- ORCID: 0000-0001-8646-2203
AD  - Health Science University, Antalya Education and Research Hospital, Department of 
      Infectious Diseases and Clinical Microbiology, Antalya 07050, Turkey.
FAU - Sayan, Murat
AU  - Sayan M
AUID- ORCID: 0000-0002-4374-7193
AD  - Faculty of Medicine, Clinical Laboratory, PCR Unit, Kocaeli University, Kocaeli, 
      Turkey.
AD  - DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.
FAU - Sanlidag, Tamer
AU  - Sanlidag T
AD  - DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.
AD  - Department of Medical Microbiology, Manisa Celal Bayar University, Manisa, 
      Turkey.
FAU - Uzun, Berna
AU  - Uzun B
AD  - DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.
AD  - Department of Mathematics, Near East University, 99138 Nicosia/TRNC, Mersin 10, 
      Turkey.
FAU - Ozsahin, Dilber Uzun
AU  - Ozsahin DU
AUID- ORCID: 0000-0002-3873-1410
AD  - DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.
AD  - Department of Biomedical Engineering, Faculty of Engineering, Near East 
      University, 99138 Nicosia/TRNC, Mersin 10, Turkey.
FAU - Ozsahin, Ilker
AU  - Ozsahin I
AUID- ORCID: 0000-0002-3141-6805
AD  - DESAM Institute, Near East University, 99138 Nicosia/TRNC, Mersin 10, Turkey.
AD  - Department of Biomedical Engineering, Faculty of Engineering, Near East 
      University, 99138 Nicosia/TRNC, Mersin 10, Turkey.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20210122
PL  - England
TA  - J Healthc Eng
JT  - Journal of healthcare engineering
JID - 101528166
RN  - 0 (Antiviral Agents)
SB  - IM
MH  - Antiviral Agents/administration & dosage/therapeutic use
MH  - Clinical Decision-Making/*methods
MH  - *Decision Support Techniques
MH  - *Fuzzy Logic
MH  - Humans
MH  - Pandemics
MH  - SARS-CoV-2
MH  - *COVID-19 Drug Treatment
PMC - PMC7831275
COIS- The authors declare no conflicts of interest.
EDAT- 2021/02/09 06:00
MHDA- 2021/02/20 06:00
PMCR- 2021/01/22
CRDT- 2021/02/08 05:37
PHST- 2020/08/28 00:00 [received]
PHST- 2020/12/25 00:00 [revised]
PHST- 2021/01/09 00:00 [accepted]
PHST- 2021/02/08 05:37 [entrez]
PHST- 2021/02/09 06:00 [pubmed]
PHST- 2021/02/20 06:00 [medline]
PHST- 2021/01/22 00:00 [pmc-release]
AID - 10.1155/2021/8864522 [doi]
PST - epublish
SO  - J Healthc Eng. 2021 Jan 22;2021:8864522. doi: 10.1155/2021/8864522. eCollection 
      2021.