PMID- 33552894
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210210
IS  - 2213-0071 (Print)
IS  - 2213-0071 (Electronic)
IS  - 2213-0071 (Linking)
VI  - 32
DP  - 2021
TI  - Interstitial pneumonia with autoimmune features: A case series and overview.
PG  - 101350
LID - 10.1016/j.rmcr.2021.101350 [doi]
LID - 101350
AB  - The topic of interstitial pneumonia with autoimmune features (IPAF) is a research 
      classification proposed by the European Respiratory Society/American Thoracic 
      Society Task Force: this includes patients with idiopathic interstitial pneumonia 
      (IIP) and clinical features, suggesting an underlying autoimmune process, but who 
      do not meet established criteria for a connective tissue disease (CTD). We aimed 
      to perform a detailed characterization of clinical, serological, and radiological 
      features for our patients with IPAF criteria. Six patients were included, and a 
      comprehensive description of these cases revealed a heterogeneous group in terms 
      of clinical and treatment options. In most patients, it was possible to identify 
      other features and disorders with an autoimmune "background," which may support 
      the inclusion of these patients in the IPAF classification. No deaths or 
      significant decline in lung function occurred, and thus no definitive diagnosis 
      of CTD could be found over 35 months of median follow-up. Therefore, IPAF is a 
      recent concept, with many questions still open in regard to its usage in the ILD 
      field.
CI  - (c) 2021 The Author(s).
FAU - Fernandes, Ana Luisa
AU  - Fernandes AL
AD  - Pulmonology Department, Hospital Pedro Hispano, Matosinhos, Portugal.
FAU - Ferreira, Jorge
AU  - Ferreira J
AD  - Pulmonology Department, Hospital Pedro Hispano, Matosinhos, Portugal.
FAU - Neves, Ines
AU  - Neves I
AD  - Pulmonology Department, Hospital Pedro Hispano, Matosinhos, Portugal.
LA  - eng
PT  - Case Reports
DEP - 20210120
PL  - England
TA  - Respir Med Case Rep
JT  - Respiratory medicine case reports
JID - 101604463
PMC - PMC7843504
OTO - NOTNLM
OT  - Connective tissue disease
OT  - Interstitial lung disease
OT  - Interstitial pneumonia with autoimmune features
COIS- All authors report no conflict of interest.
EDAT- 2021/02/09 06:00
MHDA- 2021/02/09 06:01
PMCR- 2021/01/20
CRDT- 2021/02/08 05:42
PHST- 2020/10/06 00:00 [received]
PHST- 2020/12/12 00:00 [revised]
PHST- 2021/01/13 00:00 [accepted]
PHST- 2021/02/08 05:42 [entrez]
PHST- 2021/02/09 06:00 [pubmed]
PHST- 2021/02/09 06:01 [medline]
PHST- 2021/01/20 00:00 [pmc-release]
AID - S2213-0071(21)00012-5 [pii]
AID - 101350 [pii]
AID - 10.1016/j.rmcr.2021.101350 [doi]
PST - epublish
SO  - Respir Med Case Rep. 2021 Jan 20;32:101350. doi: 10.1016/j.rmcr.2021.101350. 
      eCollection 2021.