PMID- 33555535
OWN - NLM
STAT- MEDLINE
DCOM- 20210708
LR  - 20220218
IS  - 1875-8312 (Electronic)
IS  - 1569-5794 (Print)
IS  - 1569-5794 (Linking)
VI  - 37
IP  - 6
DP  - 2021 Jun
TI  - The effect of moderate and severe COVID-19 pneumonia on short-term right 
      ventricular functions: a prospective observational single pandemic center 
      analysis.
PG  - 1883-1890
LID - 10.1007/s10554-021-02171-w [doi]
AB  - It has been reported that myocardial damage and heart failure are more common in 
      COVID-19 patients with severe symptoms. The aim of our study was to measure the 
      right ventricular functions of COVID-19 patients 30 days after their discharge, 
      and compare them to the right ventricular functions of healthy volunteers. Fifty 
      one patients with COVID-19 and 32 healthy volunteers who underwent 
      echocardiographic examinations were enrolled in our study. 29 patients were 
      treated for severe and 22 patients were treated for moderate COVID-19 pneumonia. 
      The study was conducted prospectively, in a single center, between 15 May 2020 
      and 15 July 2020. We analyzed the right ventricular functions of the patients 
      using conventional techniques and two-dimensional speckle-tracking. Right 
      ventricular end-diastolic and end-systolic area were statistically higher than 
      control group. The right ventricular fractional area change (RVFAC) was 
      significantly lesser in the patient group compared to the control group. 
      Tricuspid annular plane systolic motion (TAPSE) was within normal limits in both 
      groups, it was lower in the patient group compared to the control group. 
      Pulmonary artery pressure was found to be significantly higher in the patient 
      group. Right ventricular global longitudinal strain (RV-GLS) was lesser than the 
      control group (- 15.7 [(- 12.6)-(- 18.7)] vs. - 18.1 [(- 14.8)-(- 21)]; p 0.011). 
      Right ventricular free wall strain (RV-FWS) was lesser in the patient group 
      compared to the control group (- 16 [(- 12.7)-(- 19)] vs - 21.6 
      [(- 17)-(- 25.3)]; p < 0.001). We found subclinical right ventricular dysfunction 
      in the echocardiographies of COVID-19 patients although there were no risk 
      factors.
FAU - Gunay, Nuran
AU  - Gunay N
AUID- ORCID: 0000-0003-3779-6957
AD  - Department of Cardiology, Umraniye Training and Research Hospital, University of 
      Health Sciences, Elmalikent, Adem Yavuz Cd., Umraniye, 34764, Istanbul, Turkey. 
      nurangunaydr@gmail.com.
FAU - Demiroz, Onder
AU  - Demiroz O
AD  - Department of Cardiology, Umraniye Training and Research Hospital, University of 
      Health Sciences, Elmalikent, Adem Yavuz Cd., Umraniye, 34764, Istanbul, Turkey.
FAU - Kahyaoglu, Muzaffer
AU  - Kahyaoglu M
AD  - Department of Cardiology, Gaziantep Abdulkadir Yuksel State Hospital, Gaziantep, 
      Turkey.
FAU - Baslilar, Seyma
AU  - Baslilar S
AD  - Department of Pulmonology, Umraniye Training and Research Hospital, University of 
      Health Sciences, Istanbul, Turkey.
FAU - Aydin, Mehtap
AU  - Aydin M
AD  - Department of Infectious Diseases and Clinical Microbiology, Umraniye Training 
      and Research Hospital, University of Health Sciences, Istanbul, Turkey.
FAU - Ozer, Merve Caglar
AU  - Ozer MC
AD  - Department of Infectious Diseases and Clinical Microbiology, Umraniye Training 
      and Research Hospital, University of Health Sciences, Istanbul, Turkey.
FAU - Ileri, Cigdem
AU  - Ileri C
AD  - Department of Cardiology, Umraniye Training and Research Hospital, University of 
      Health Sciences, Elmalikent, Adem Yavuz Cd., Umraniye, 34764, Istanbul, Turkey.
FAU - Keskin, Muhammed
AU  - Keskin M
AD  - Department of Cardiology, Istanbul Sultan Abdulhamid Han Education and Research 
      Hospital, University of Health Sciences, Istanbul, Turkey.
FAU - Bayam, Emrah
AU  - Bayam E
AD  - Department of Cardiology, Kartal Kosuyolu Heart Training and Research Hopital, 
      Istanbul, Turkey.
FAU - Uyan, Cihangir
AU  - Uyan C
AD  - Department of Cardiology, Umraniye Training and Research Hospital, University of 
      Health Sciences, Elmalikent, Adem Yavuz Cd., Umraniye, 34764, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20210208
PL  - United States
TA  - Int J Cardiovasc Imaging
JT  - The international journal of cardiovascular imaging
JID - 100969716
SB  - IM
MH  - COVID-19/epidemiology/*physiopathology
MH  - Case-Control Studies
MH  - *Echocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pandemics
MH  - Pneumonia, Viral/epidemiology/*physiopathology/virology
MH  - Prospective Studies
MH  - SARS-CoV-2
MH  - Severity of Illness Index
MH  - Turkey/epidemiology
MH  - Ventricular Dysfunction, Right/*diagnostic imaging/epidemiology/*physiopathology
PMC - PMC7868518
OTO - NOTNLM
OT  - COVID-19
OT  - Comorbidity
OT  - Echocardiography
OT  - Right ventricular function
OT  - Speckle tracking echocardiography
COIS- There are no conflicts of interest.
EDAT- 2021/02/09 06:00
MHDA- 2021/07/09 06:00
PMCR- 2021/02/08
CRDT- 2021/02/08 12:14
PHST- 2020/11/09 00:00 [received]
PHST- 2021/01/22 00:00 [accepted]
PHST- 2021/02/09 06:00 [pubmed]
PHST- 2021/07/09 06:00 [medline]
PHST- 2021/02/08 12:14 [entrez]
PHST- 2021/02/08 00:00 [pmc-release]
AID - 10.1007/s10554-021-02171-w [pii]
AID - 2171 [pii]
AID - 10.1007/s10554-021-02171-w [doi]
PST - ppublish
SO  - Int J Cardiovasc Imaging. 2021 Jun;37(6):1883-1890. doi: 
      10.1007/s10554-021-02171-w. Epub 2021 Feb 8.