PMID- 33559776
OWN - NLM
STAT- MEDLINE
DCOM- 20210813
LR  - 20210813
IS  - 1434-9949 (Electronic)
IS  - 0770-3198 (Linking)
VI  - 40
IP  - 9
DP  - 2021 Sep
TI  - Spondyloarthritis in North Africa: an update.
PG  - 3401-3410
LID - 10.1007/s10067-021-05630-w [doi]
AB  - Spondyloarthritis (SpA) has been less well studied than rheumatoid arthritis in 
      North Africa, due to a belief that it is rare and benign in certain populations. 
      The main genetic trait of SpA is its association with human leukocyte antigen 
      (HLA)-B27. The distribution of this allele largely explains the prevalence and 
      severity of SpA. The prevalence of HLA-B27 in the general population of North 
      Africa is estimated at about 4%, and rises to about 60% among people affected 
      with SpA. Coxitis is one of the main features of North African SpA, but the 
      response to treatment is comparable to the literature from the West. The major 
      challenge in North Africa remains accessibility to specialized care and means of 
      early diagnosis. Prevalent infections in North Africa do not seem to be a major 
      obstacle to optimal treatment strategies.
CI  - (c) 2021. International League of Associations for Rheumatology (ILAR).
FAU - Slimani, Samy
AU  - Slimani S
AUID- ORCID: 0000-0001-9332-3551
AD  - Atlas Clinic, Batna, Algeria. slimani@dr.com.
FAU - Hamdi, Wafa
AU  - Hamdi W
AD  - Service de rhumatologie institut M. T Kassab. UR17SP04 Faculte de medecine de 
      Tunis, Universite Tunis el Manar, Tunis, Tunisia.
FAU - Nassar, Kawtar
AU  - Nassar K
AD  - Service de rhumatologie, Centre Hospitalier Universitaire Ibn Rochd, Faculte de 
      medecine et de pharmacie, Universite Hassan II, Casablanca, Morocco.
FAU - Kalla, Asgar Ali
AU  - Kalla AA
AD  - Department of Medicine, University of Cape Town, Cape Town, South Africa.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210209
PL  - Germany
TA  - Clin Rheumatol
JT  - Clinical rheumatology
JID - 8211469
RN  - 0 (HLA-B27 Antigen)
SB  - IM
CIN - Clin Rheumatol. 2021 Jun;40(6):2513. PMID: 33763800
MH  - Africa, Northern/epidemiology
MH  - Early Diagnosis
MH  - HLA-B27 Antigen/genetics
MH  - Humans
MH  - Prevalence
MH  - *Spondylarthritis/diagnosis/epidemiology
OTO - NOTNLM
OT  - Epidemiology
OT  - HLA-B27
OT  - North Africa
OT  - Spondyloarthritis
EDAT- 2021/02/10 06:00
MHDA- 2021/08/14 06:00
CRDT- 2021/02/09 08:47
PHST- 2020/07/14 00:00 [received]
PHST- 2021/02/02 00:00 [accepted]
PHST- 2020/12/06 00:00 [revised]
PHST- 2021/02/10 06:00 [pubmed]
PHST- 2021/08/14 06:00 [medline]
PHST- 2021/02/09 08:47 [entrez]
AID - 10.1007/s10067-021-05630-w [pii]
AID - 10.1007/s10067-021-05630-w [doi]
PST - ppublish
SO  - Clin Rheumatol. 2021 Sep;40(9):3401-3410. doi: 10.1007/s10067-021-05630-w. Epub 
      2021 Feb 9.