PMID- 33561473 OWN - NLM STAT- MEDLINE DCOM- 20220228 LR - 20220228 IS - 1527-9995 (Electronic) IS - 0090-4295 (Linking) VI - 153 DP - 2021 Jul TI - Challenging Case of Holmium Laser Enucleation of the Prostate after Prior Prostatic Focal Laser Ablations and Rezum. PG - 358 LID - S0090-4295(21)00155-2 [pii] LID - 10.1016/j.urology.2021.01.046 [doi] AB - BACKGROUND: Holmium laser enucleation of the prostate (HoLEP) is an effective, size independent procedure for management of benign prostatic hyperplasia (BPH).(1) Additionally, HoLEP is able to be performed successfully after prior surgical BPH treatments without complication and a low rate of long term retreatment.(2) OBJECTIVES: To demonstrate challenging case of HoLEP in a patient with multiple, prior ablative BPH surgeries. MATERIAL: A 63 year old male with refractory lower urinary tract symptoms after 2 focal laser ablations, one Rezum treatment, and medications (silodosin 8 mg and tadalfil 5 mg) presented to our clinic with obstructive lateral lobe BPH. The prostate was approximately 50 ml on digital rectal exam and preoperative cystoscopy demonstrated prostatic urethral calcifications and lateral lobe hypertrophy. Preoperative AUA symptom score (AUAss) was 12, peak urinary flow was 5.3 ml/s. A HoLEP was performed to alleviate the patients lower urinary tract symptoms and allow him to stop his medications. RESULTS: Total procedure time was 44 minutes, with enucleation time of 20 minutes and morcellation time of 1 minute. The HoLEP was started as a 2-cut technique, however due to poor surgical planes we changed to top-down technique.(3) There was a small, posterior, nonclinically significant capsular perforation. Five grams of benign adenoma were removed. Patient was discharged on the day of surgery. Catheter was removed on postoperative day four due to patient desiring to return home (over 150 miles away) for catheter removal, instead of having it done in our clinic on postoperative day one. At most recent follow-up, AUAss was 5 and peak urinary flow was 13.2 ml/s. CONCLUSION: HoLEP can be performed after prior, multiple BPH treatments successfully. These can prove to be more challenging cases. Prior ablative techniques can lead to fibrosis of transition zone tissue and distort the natural plane between adenoma and surgical capsule. CI - Copyright (c) 2021 Elsevier Inc. All rights reserved. FAU - Agarwal, Deepak K AU - Agarwal DK AD - Department of Urology, Indiana University School of Medicine, Indianapolis, IN. FAU - Krambeck, Amy E AU - Krambeck AE AD - Department of Urology, Indiana University School of Medicine, Indianapolis, IN. Electronic address: gecoots2@gmail.com. LA - eng PT - Case Reports PT - Video-Audio Media DEP - 20210206 PL - United States TA - Urology JT - Urology JID - 0366151 RN - 0 (Steam) SB - IM MH - Ablation Techniques/*methods MH - Humans MH - *Laser Therapy MH - Lasers, Solid-State/*therapeutic use MH - Male MH - Middle Aged MH - Prostatectomy/*methods MH - Prostatic Hyperplasia/*surgery MH - Reoperation MH - Steam EDAT- 2021/02/10 06:00 MHDA- 2022/03/01 06:00 CRDT- 2021/02/09 20:09 PHST- 2020/09/11 00:00 [received] PHST- 2021/01/16 00:00 [revised] PHST- 2021/01/25 00:00 [accepted] PHST- 2021/02/10 06:00 [pubmed] PHST- 2022/03/01 06:00 [medline] PHST- 2021/02/09 20:09 [entrez] AID - S0090-4295(21)00155-2 [pii] AID - 10.1016/j.urology.2021.01.046 [doi] PST - ppublish SO - Urology. 2021 Jul;153:358. doi: 10.1016/j.urology.2021.01.046. Epub 2021 Feb 6.