PMID- 33565303
OWN - NLM
STAT- MEDLINE
DCOM- 20211112
LR  - 20221207
IS  - 2501-062X (Electronic)
IS  - 1220-4749 (Linking)
VI  - 59
IP  - 2
DP  - 2021 Jun 1
TI  - Effects of an actual insulin injection demonstration on insulin acceptance among 
      patients with T2DM: a pragmatic randomized controlled trial.
PG  - 151-158
LID - 10.2478/rjim-2020-0040 [doi]
AB  - Introduction. Insulin injection refusal is a challenge when initiating insulin 
      therapy. This study aimed to investigate the effects of an actual insulin 
      injection demonstration on insulin acceptance in patients with type 2 diabetes 
      mellitus (T2DM).Methods. A pragmatic randomised controlled trial (RCT) was 
      conducted. The participants were patients with T2DM aged 18-65 years old. The 
      control group (CG) received an educational programme regarding T2DM. The 
      intervention group (IG) received the educational programme and actual insulin 
      injection demonstration (a physician-led sample insulin injection using an 
      insulin pen). The main outcome was immediate insulin acceptance. Insulin 
      adherence, glycated haemoglobin (HbA1c), and adverse effects of insulin were 
      evaluated at three months after the intervention.Results. Forty-nine participants 
      with T2DM were allocated to the IG (n = 24) and the CG (n = 25). The immediate 
      insulin acceptance was significantly higher in the IG (79.17%, n = 19) than the 
      CG (24.00%, n = 6; p < 0.05; RR 3.30, 95% CI 1.59 to 6.82). At the three-month 
      follow-up, the insulin adherence was significantly different between the two 
      groups (IG: 75.00%, n = 18 vs CG: 20.00%, n = 5; p < 0.05; RR 3.75, 95% CI 1.66 
      to 8.49). Adverse effects of insulin, HbA1c levels, and changes in HbA1c levels 
      between the IG and CG were not different.Conclusion. The physician-led actual 
      insulin injection demonstration is effective for increasing insulin acceptance 
      among participants with T2DM.
CI  - (c) 2021 Atthayaporn Choomai et al., published by Sciendo.
FAU - Choomai, Atthayaporn
AU  - Choomai A
AD  - Thasala Hospital, Thasala, Nakhon Si Thammarat, Thailand.
FAU - Wattanapisit, Apichai
AU  - Wattanapisit A
AD  - School of Medicine, Walailak University, Thasala, Nakhon Si Thammarat, Thailand.
AD  - Walailak University Hospital, Thasala, Nakhon Si Thammarat, Thailand.
FAU - Tiangtam, Orathai
AU  - Tiangtam O
AD  - Thasala Hospital, Thasala, Nakhon Si Thammarat, Thailand.
AD  - Thonburi Thung Song Hospital, Thung Song, Nakhon Si Thammarat, Thailand.
LA  - eng
PT  - Journal Article
PT  - Pragmatic Clinical Trial
PT  - Randomized Controlled Trial
DEP - 20210508
PL  - Germany
TA  - Rom J Intern Med
JT  - Romanian journal of internal medicine = Revue roumaine de medecine interne
JID - 9304507
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Hypoglycemic Agents)
RN  - 0 (Insulin)
RN  - 0 (hemoglobin A1c protein, human)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Diabetes Mellitus, Type 2/blood/*drug therapy/psychology
MH  - Fear
MH  - Female
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - Hypoglycemic Agents/*administration & dosage/adverse effects
MH  - Insulin/*administration & dosage/adverse effects
MH  - Male
MH  - Medication Adherence
MH  - Middle Aged
MH  - *Patient Acceptance of Health Care
MH  - Patient Education as Topic/*methods
MH  - Physician's Role
MH  - Treatment Refusal/psychology
MH  - Young Adult
OTO - NOTNLM
OT  - injection demonstration
OT  - insulin
OT  - insulin acceptance
OT  - treatment
OT  - type 2 diabetes mellitus
EDAT- 2021/02/11 06:00
MHDA- 2021/11/16 06:00
CRDT- 2021/02/10 08:17
PHST- 2020/09/22 00:00 [received]
PHST- 2021/02/11 06:00 [pubmed]
PHST- 2021/11/16 06:00 [medline]
PHST- 2021/02/10 08:17 [entrez]
AID - rjim-2020-0040 [pii]
AID - 10.2478/rjim-2020-0040 [doi]
PST - epublish
SO  - Rom J Intern Med. 2021 May 8;59(2):151-158. doi: 10.2478/rjim-2020-0040. Print 
      2021 Jun 1.