PMID- 33571604
OWN - NLM
STAT- MEDLINE
DCOM- 20210628
LR  - 20240227
IS  - 1873-1570 (Electronic)
IS  - 0300-9572 (Linking)
VI  - 162
DP  - 2021 May
TI  - Health-related quality of life after out-of-hospital cardiac arrest - a five-year 
      follow-up study.
PG  - 372-380
LID - S0300-9572(21)00045-9 [pii]
LID - 10.1016/j.resuscitation.2021.01.036 [doi]
AB  - BACKGROUND: Health-related quality of life (HRQoL) is affected after 
      out-of-hospital cardiac arrest (OHCA), but data several years after the arrest 
      are lacking. We assessed long-term HRQoL in OHCA survivors and how known outcome 
      predictors impact HRQoL. METHODS: In adult OHCA survivors, HRQoL was assessed 
      five years post arrest using Short-form 36 (SF-36), EQ-5D-3 L (EQ-5D) and 
      Hospital Anxiety and Depression Scale (HADS) among others. Results were compared 
      to the next of kins' estimates and to a Norwegian reference population. RESULTS: 
      Altogether 96 survivors were included mean 5.3 (range 3.6-7.2) years after OHCA. 
      HRQoL compared well to the reference population, except for lower score for 
      general health with 67.2 (95%CI (62.1; 72.3) vs. 72.9 (71.9; 74.0)), p = 0.03. 
      Younger (</=58 years) vs. older survivors scored lower for general health with mean 
      (SD) of 62.1 (27.5) vs. 73.0 (19.5), p = 0.03, vitality (55.2 (20.5) vs. 64.6 
      (17.3), p = 0.02, social functioning (75.3 (28.7) vs. 94.1 (13.5), p < 0.001 and 
      mental component summary (49.0 (9.9) vs. 55.8 (6.7), p < 0.001. They scored 
      higher for HADS-anxiety (4.8 (3.6 vs. 2.7 (2.5), p = 0.001, and had lower EQ-5D 
      index (0.72 (0.34) vs. 0.84 (0.19), p = 0.04. Early vs. late awakeners had higher 
      EQ-5D index (0.82 (0.23) vs. 0.71 (0.35), p = 0.04 and lower HADS-depression 
      scores (2.5 (2.9) vs. 3.8 (2.3), p = 0.04. Next of kin estimated HRQoL similar to 
      the survivors' own estimates. CONCLUSIONS: HRQoL five years after OHCA was good 
      and mainly comparable to a matched reference population. Stratified analyses 
      revealed impaired HRQoL among younger survivors and those awakening late, mainly 
      for mental domains.
CI  - Copyright (c) 2021 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - Wimmer, Henning
AU  - Wimmer H
AD  - Department of Acute Medicine, Oslo University Hospital, Ulleval, Norway; 
      Institute of Clinical Medicine, University of Oslo, Norway. Electronic address: 
      henning.wimmer@mailbox.org.
FAU - Lundqvist, Christofer
AU  - Lundqvist C
AD  - Department of Neurology, Akershus University Hospital, Norway; Institute of 
      Clinical Medicine, University of Oslo, Norway; Health Services Research Unit, 
      Akershus University Hospital, Norway.
FAU - Saltyte Benth, Jurate
AU  - Saltyte Benth J
AD  - Institute of Clinical Medicine, University of Oslo, Norway; Health Services 
      Research Unit, Akershus University Hospital, Norway.
FAU - Stavem, Knut
AU  - Stavem K
AD  - Institute of Clinical Medicine, University of Oslo, Norway; Health Services 
      Research Unit, Akershus University Hospital, Norway; Department of Pulmonary 
      Medicine, Medical Division, Akershus University Hospital, Norway.
FAU - Andersen, Geir O
AU  - Andersen GO
AD  - Department of Cardiology, Oslo University Hospital, Ulleval, Norway.
FAU - Henriksen, Julia
AU  - Henriksen J
AD  - Department of Neurology, Oslo University Hospital, Ulleval, Norway.
FAU - Draegni, Tomas
AU  - Draegni T
AD  - Institute of Clinical Medicine, University of Oslo, Norway; Department of 
      Research and Development, Oslo University Hospital, Ulleval, Norway.
FAU - Sunde, Kjetil
AU  - Sunde K
AD  - Institute of Clinical Medicine, University of Oslo, Norway; Department of 
      Anaesthesiology, Oslo University Hospital, Ulleval, Norway.
FAU - Nakstad, Espen R
AU  - Nakstad ER
AD  - Department of Acute Medicine, Oslo University Hospital, Ulleval, Norway.
LA  - eng
PT  - Journal Article
DEP - 20210208
PL  - Ireland
TA  - Resuscitation
JT  - Resuscitation
JID - 0332173
SB  - IM
CIN - Resuscitation. 2021 May;162:428-430. PMID: 33711399
MH  - Adult
MH  - Follow-Up Studies
MH  - Humans
MH  - *Out-of-Hospital Cardiac Arrest
MH  - *Quality of Life
MH  - Surveys and Questionnaires
MH  - Survivors
OTO - NOTNLM
OT  - Long-term follow-up
OT  - Out-of-hospital cardiac arrest
OT  - Outcome
OT  - Quality of life
EDAT- 2021/02/12 06:00
MHDA- 2021/06/29 06:00
CRDT- 2021/02/11 20:11
PHST- 2020/09/23 00:00 [received]
PHST- 2020/12/14 00:00 [revised]
PHST- 2021/01/23 00:00 [accepted]
PHST- 2021/02/12 06:00 [pubmed]
PHST- 2021/06/29 06:00 [medline]
PHST- 2021/02/11 20:11 [entrez]
AID - S0300-9572(21)00045-9 [pii]
AID - 10.1016/j.resuscitation.2021.01.036 [doi]
PST - ppublish
SO  - Resuscitation. 2021 May;162:372-380. doi: 10.1016/j.resuscitation.2021.01.036. 
      Epub 2021 Feb 8.