PMID- 33574574
OWN - NLM
STAT- MEDLINE
DCOM- 20220331
LR  - 20221023
IS  - 1476-5489 (Electronic)
IS  - 0955-9930 (Print)
IS  - 0955-9930 (Linking)
VI  - 34
IP  - 2
DP  - 2022 Mar
TI  - Increase in searches for erectile dysfunction during winter: seasonal variation 
      evidence from Google Trends in the United States.
PG  - 172-176
LID - 10.1038/s41443-020-00397-1 [doi]
AB  - Several diseases associated with erectile dysfunction (ED), such as type 2 
      diabetes mellitus (T2DM) and coronary artery disease (CAD), are known to have 
      seasonal variation, with increased incidence during winter months. However, no 
      literature exists on whether this chronological-seasonal evolution is also 
      present within ED symptomatology. We hypothesized ED would follow the seasonal 
      pattern of its lifestyle-influenced comorbid conditions and exhibit increased 
      incidence during winter months. In order to investigate the seasonal variation of 
      ED in the United States between 2009 and 2019, Internet search query data were 
      obtained using Google Trends. Normalized search volume was determined during the 
      winter and summer seasons for ED, other diseases known to be significantly 
      associated with ED (T2DM and CAD), kidney stones (positive control), and prostate 
      cancer (negative control). There were significantly more internet search queries 
      for ED during the winter than during the summer (p = 0.001). CAD and T2DM also 
      had significantly increased search volume during winter months compared to summer 
      months (p < 0.001 and p = 0.011, respectively). By contrast, searches for kidney 
      stones were significantly increased in the summer than in the winter (p < 0.001). 
      There was no significant seasonal variation in the relative search frequency for 
      prostate cancer (p = 0.75). In conclusion, Google Trends internet search data 
      across a ten-year period in the United States suggested a seasonal variation in 
      ED, which implies an increase in ED during winter. This novel finding in ED 
      epidemiology may help increase awareness of ED's associated lifestyle risk 
      factors, which may facilitate early medical evaluation and treatment for those at 
      risk of both ED and cardiovascular disease.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer Nature Limited part of 
      Springer Nature.
FAU - Garijo, Belen Mora
AU  - Garijo BM
AUID- ORCID: 0000-0002-7083-2684
AD  - Department of Urology, University of Miami Miller School of Medicine, Miami, FL, 
      USA. bxm109@med.miami.edu.
FAU - Katz, Jonathan E
AU  - Katz JE
AD  - Department of Urology, University of Miami Miller School of Medicine, Miami, FL, 
      USA.
FAU - Greer, Aubrey
AU  - Greer A
AD  - Department of Urology, University of Miami Miller School of Medicine, Miami, FL, 
      USA.
FAU - Gonzalgo, Mia
AU  - Gonzalgo M
AD  - Department of Urology, University of Miami Miller School of Medicine, Miami, FL, 
      USA.
FAU - Lopez, Alejandro Garcia
AU  - Lopez AG
AD  - Department of Urology, University of Miami Miller School of Medicine, Miami, FL, 
      USA.
FAU - Deane, Leslie
AU  - Deane L
AD  - Department of Urology, University of Miami Miller School of Medicine, Miami, FL, 
      USA.
FAU - Ramasamy, Ranjith
AU  - Ramasamy R
AD  - Department of Urology, University of Miami Miller School of Medicine, Miami, FL, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20210211
PL  - England
TA  - Int J Impot Res
JT  - International journal of impotence research
JID - 9007383
SB  - IM
MH  - *Diabetes Mellitus, Type 2
MH  - *Erectile Dysfunction/epidemiology
MH  - Humans
MH  - Internet
MH  - Male
MH  - Risk Factors
MH  - Search Engine
MH  - Seasons
MH  - United States/epidemiology
PMC - PMC8964410
COIS- The authors declare that they have no conflict of interest.
EDAT- 2021/02/13 06:00
MHDA- 2022/04/01 06:00
PMCR- 2021/02/11
CRDT- 2021/02/12 06:02
PHST- 2020/08/11 00:00 [received]
PHST- 2020/12/02 00:00 [accepted]
PHST- 2020/11/10 00:00 [revised]
PHST- 2021/02/13 06:00 [pubmed]
PHST- 2022/04/01 06:00 [medline]
PHST- 2021/02/12 06:02 [entrez]
PHST- 2021/02/11 00:00 [pmc-release]
AID - 10.1038/s41443-020-00397-1 [pii]
AID - 397 [pii]
AID - 10.1038/s41443-020-00397-1 [doi]
PST - ppublish
SO  - Int J Impot Res. 2022 Mar;34(2):172-176. doi: 10.1038/s41443-020-00397-1. Epub 
      2021 Feb 11.