PMID- 33592731
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20210218
LR  - 20210218
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 225
DP  - 2021 Apr 1
TI  - Deep eutectic solvent-based clean-up/vortex-assisted emulsification liquid-liquid 
      microextraction: Application for multi-residue analysis of 16 pesticides in olive 
      oils.
PG  - 121983
LID - S0039-9140(20)31274-1 [pii]
LID - 10.1016/j.talanta.2020.121983 [doi]
AB  - A new hydrophobic deep eutectic solvent (DES) composed of thymol and vanillin 
      (1:1) was prepared and used as the extraction solvent in vortex-assisted 
      emulsification liquid-liquid microextraction of 16 pesticides in olive oil before 
      GC-muECD analysis. Due to the complexity of oil samples, a DES-based liquid-liquid 
      solvent system (n-hexane/acetonitrile/DES) was developed to achieve an effective 
      clean-up. Among the four examined hydrophilic DESs, [choline chloride]:[urea] led 
      to improved sensitivity, and clean chromatograms with low noise and drift from 
      the sample matrix. Besides, the effect of the significant factors such as 
      extraction solvent volume, pH, ionic strength, and vortex time was investigated. 
      At the optimized conditions, the validation parameters such as linear range 
      0.04-250 mug kg(-1), the limits of detection of 0.01-0.08 mug kg(-1), intra-day, 
      and inter-day relative standard deviations (RSDs) < 6.8 and < 9.7%, were 
      obtained. This method was followed by GC-muECD and applied to determine pesticides 
      in five olive oil samples. The relative recoveries were in the range of 
      63.1-119.4%.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Soltani, Sara
AU  - Soltani S
AD  - School of Chemistry, College of Science, University of Tehran, Tehran, Iran.
FAU - Sereshti, Hassan
AU  - Sereshti H
AD  - School of Chemistry, College of Science, University of Tehran, Tehran, Iran. 
      Electronic address: sereshti@ut.ac.ir.
FAU - Nouri, Nina
AU  - Nouri N
AD  - School of Chemistry, College of Science, University of Tehran, Tehran, Iran.
LA  - eng
PT  - Journal Article
DEP - 20201208
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
SB  - IM
OTO - NOTNLM
OT  - Hydrophobic deep eutectic solvent
OT  - Multi-residue pesticide analysis
OT  - Olive oil
OT  - Thymol/vanillin
EDAT- 2021/02/18 06:00
MHDA- 2021/02/18 06:01
CRDT- 2021/02/17 01:00
PHST- 2020/09/17 00:00 [received]
PHST- 2020/11/12 00:00 [revised]
PHST- 2020/12/04 00:00 [accepted]
PHST- 2021/02/17 01:00 [entrez]
PHST- 2021/02/18 06:00 [pubmed]
PHST- 2021/02/18 06:01 [medline]
AID - S0039-9140(20)31274-1 [pii]
AID - 10.1016/j.talanta.2020.121983 [doi]
PST - ppublish
SO  - Talanta. 2021 Apr 1;225:121983. doi: 10.1016/j.talanta.2020.121983. Epub 2020 Dec 
      8.