PMID- 33594435
OWN - NLM
STAT- MEDLINE
DCOM- 20211018
LR  - 20211028
IS  - 1471-9053 (Electronic)
IS  - 0032-0781 (Linking)
VI  - 62
IP  - 4
DP  - 2021 Sep 24
TI  - EIN3-Mediated Ethylene Signaling Attenuates Auxin Response during Hypocotyl 
      Thermomorphogenesis.
PG  - 708-720
LID - 10.1093/pcp/pcab028 [doi]
AB  - The gaseous phytohormone ethylene plays vital roles in diverse developmental and 
      environmental adaptation processes, such as fruit ripening, seedling 
      establishment, mechanical stress tolerance and submergence escape. It is also 
      known that in the light, ethylene promotes hypocotyl growth by stimulating the 
      expression of PHYTOCHROME INTERACTING FACTOR3 (PIF3) transcription factor, which 
      triggers microtubule reorganization during hypocotyl cell elongation. In 
      particular, ethylene has been implicated in plant responses to warm temperatures 
      in recent years. However, it is currently unclear how ethylene signals are 
      functionally associated with hypocotyl thermomorphogenesis at the molecular 
      level. Here, we show that ETHYLENE-INSENSITIVE3 (EIN3)-mediated ethylene signals 
      attenuate hypocotyl thermomorphogenesis by suppressing auxin response. At warm 
      temperatures, when the activity of the PIF4 thermomorphogenesis promoter is 
      prominently high, the ethylene-activated EIN3 transcription factor directly 
      induces the transcription of ARABIDOPSIS PP2C CLADE D7 (APD7) gene encoding a 
      protein phosphatase that inactivates the plasma membrane (PM) H+-ATPase proton 
      pumps. In conjunction with the promotive role of the PM H+-ATPases in hypocotyl 
      cell elongation, our observations strongly support that the EIN3-directed 
      induction of APD7 gene is linked with the suppression of auxin-induced cell 
      expansion, leading to the reduction in thermomorphogenic hypocotyl growth. Our 
      data demonstrate that APD7 acts as a molecular hub that integrates ethylene and 
      auxin signals into hypocotyl thermomorphogenesis. We propose that the 
      ethylene-auxin signaling crosstalks via the EIN3-APD7 module facilitate the 
      fine-tuning of hypocotyl thermomorphogenesis under natural environments, which 
      often fluctuate in a complex manner.
CI  - (c) The Author(s) 2021. Published by Oxford University Press on behalf of Japanese 
      Society of Plant Physiologists. All rights reserved. For permissions, please 
      email: journals.permissions@oup.com.
FAU - Kim, Jae Young
AU  - Kim JY
AD  - Department of Chemistry, Seoul National University, Seoul 08826, Korea.
FAU - Park, Young-Joon
AU  - Park YJ
AUID- ORCID: 0000-0003-0513-1766
AD  - Department of Chemistry, Seoul National University, Seoul 08826, Korea.
FAU - Lee, June-Hee
AU  - Lee JH
AD  - Department of Chemistry, Seoul National University, Seoul 08826, Korea.
FAU - Kim, Zee Hwan
AU  - Kim ZH
AD  - Department of Chemistry, Seoul National University, Seoul 08826, Korea.
FAU - Park, Chung-Mo
AU  - Park CM
AUID- ORCID: 0000-0001-8841-8361
AD  - Department of Chemistry, Seoul National University, Seoul 08826, Korea.
AD  - Plant Genomics and Breeding Institute, Seoul National University, Seoul 08826, 
      Korea.
LA  - eng
GR  - NRF-2018R1A2A1A19020840/The Leaping Research/
GR  - National Research Foundation of Korea (NRF)/
PT  - Journal Article
PL  - Japan
TA  - Plant Cell Physiol
JT  - Plant & cell physiology
JID - 9430925
RN  - 0 (Arabidopsis Proteins)
RN  - 0 (Basic Helix-Loop-Helix Transcription Factors)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (EIN3 protein, Arabidopsis)
RN  - 0 (Ethylenes)
RN  - 0 (Indoleacetic Acids)
RN  - 0 (PIF4 protein, Arabidopsis)
RN  - 0 (Transcription Factors)
RN  - 91GW059KN7 (ethylene)
RN  - EC 3.1.3.16 (At5g02760 protein, Arabidopsis)
RN  - EC 3.1.3.16 (Phosphoprotein Phosphatases)
SB  - IM
MH  - Arabidopsis/*physiology
MH  - Arabidopsis Proteins/genetics/*metabolism
MH  - Basic Helix-Loop-Helix Transcription Factors/genetics/metabolism
MH  - DNA-Binding Proteins/genetics/*metabolism
MH  - Ethylenes/*metabolism
MH  - Gene Expression Regulation, Plant
MH  - Hypocotyl/growth & development/*physiology
MH  - Indoleacetic Acids/metabolism
MH  - Phosphoprotein Phosphatases/genetics/metabolism
MH  - Plants, Genetically Modified
MH  - Signal Transduction
MH  - Temperature
MH  - Transcription Factors/genetics/*metabolism
OTO - NOTNLM
OT  - Arabidopsis thaliana
OT  - APD7
OT  - EIN3
OT  - Ethylene
OT  - PIF4
OT  - Thermomorphogenesis
EDAT- 2021/02/18 06:00
MHDA- 2021/10/21 06:00
CRDT- 2021/02/17 05:57
PHST- 2020/10/21 00:00 [received]
PHST- 2021/02/10 00:00 [accepted]
PHST- 2021/02/18 06:00 [pubmed]
PHST- 2021/10/21 06:00 [medline]
PHST- 2021/02/17 05:57 [entrez]
AID - 6140783 [pii]
AID - 10.1093/pcp/pcab028 [doi]
PST - ppublish
SO  - Plant Cell Physiol. 2021 Sep 24;62(4):708-720. doi: 10.1093/pcp/pcab028.