PMID- 33609999
OWN - NLM
STAT- MEDLINE
DCOM- 20210323
LR  - 20210323
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 213
DP  - 2021 Apr 15
TI  - Residue behavior and dietary risk assessment of six pesticides in pak choi using 
      QuEChERS method coupled with UPLC-MS/MS.
PG  - 112022
LID - S0147-6513(21)00133-0 [pii]
LID - 10.1016/j.ecoenv.2021.112022 [doi]
AB  - A reliable and simple modified QuEChERS method with UPLC-MS/MS was developed for 
      the simultaneous determination of six pesticides (dimethomorph, imidaclothiz, 
      lufenuron, methoxyfenozide, pyridaben, spinetoram) and their metabolites in pak 
      choi. Method validation indicated good linearity (R(2) >/= 0.99), accuracy 
      (recoveries of 75%-112%), sensitivity (limits of quantification, 
      0.002-0.01 mg kg(-1)), and precision (relative standard deviations </= 21%), and 
      matrix effects were -36-28%. The half-lives of the six pesticides in pak choi 
      were 2.2-12 d under open field and greenhouse conditions. Considering the short 
      growth cycle of pak choi, the terminal residue levels (0.046-7.8 mg kg(-1)) and 
      the relevant maximum residue limits (MRLs) of some countries, 5 d was recommended 
      as the pre-harvest interval for the six pesticides on pak choi. Dietary risk 
      assessment revealed that the risk quotients were 3.1%-58% for different gender 
      and age groups in China, indicating none unacceptable public health risk for 
      general population. The results showed that all the six pesticides degraded 
      faster and the terminal residues were much lower under open field conditions than 
      those under greenhouse conditions, which was mainly due to the influence of 
      rainfall, sunlight and other environmental factors. This work was thus 
      significant in assessing the dissipation fate and food safety risks of the six 
      pesticides on pak choi and facilitated the establishment of maximum residue 
      limits.
CI  - Copyright (c) 2021 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Tang, Hongxia
AU  - Tang H
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China.
FAU - Ma, Lin
AU  - Ma L
AD  - Shanghai Agriculture Technical Extension Service Center, Shanghai 201103, PR 
      China.
FAU - Huang, Jiaqing
AU  - Huang J
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China.
FAU - Li, Yubo
AU  - Li Y
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China.
FAU - Liu, Zehui
AU  - Liu Z
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China.
FAU - Meng, Dianying
AU  - Meng D
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China.
FAU - Wen, Guangyue
AU  - Wen G
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China.
FAU - Dong, Maofeng
AU  - Dong M
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China. Electronic address: dmf385@163.com.
FAU - Wang, Weimin
AU  - Wang W
AD  - Pesticide Safety Evaluation Research Center, Institute for Agro-food Standards 
      and Testing Technology, Shanghai Academy of Agricultural Sciences, Shanghai 
      201106, PR China. Electronic address: 173915883@qq.com.
FAU - Zhao, Li
AU  - Zhao L
AD  - Shanghai Agriculture Technical Extension Service Center, Shanghai 201103, PR 
      China.
LA  - eng
PT  - Journal Article
DEP - 20210218
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Hydrazines)
RN  - 0 (Juvenile Hormones)
RN  - 0 (Macrolides)
RN  - 0 (Pesticide Residues)
RN  - 0 (Pesticides)
RN  - 62A22651ZX (methoxyfenozide)
RN  - YGZ1037ELN (spinetoram)
SB  - IM
MH  - Brassica/*chemistry
MH  - China
MH  - Chromatography, High Pressure Liquid
MH  - Chromatography, Liquid/methods
MH  - Dietary Exposure/*statistics & numerical data
MH  - Food Safety
MH  - Hydrazines
MH  - Juvenile Hormones
MH  - Macrolides
MH  - Pesticide Residues/*analysis
MH  - Pesticides/*analysis/toxicity
MH  - Risk Assessment
MH  - Tandem Mass Spectrometry/methods
OTO - NOTNLM
OT  - Dimethomorph (PubChem CID: 5889665)
OT  - Dissipation
OT  - Imidaclothiz (PubChem CID: 184601)
OT  - Lufenuron (PubChem CID: 71777)
OT  - Methoxyfenozide (PubChem CID: 105010)
OT  - Pak choi
OT  - Pesticides
OT  - Pyridaben (PubChem CID: 91754)
OT  - Residues level
OT  - Safety evaluation
OT  - Spinetoram (PubChem CID: 53297414)
EDAT- 2021/02/21 06:00
MHDA- 2021/03/24 06:00
CRDT- 2021/02/20 20:14
PHST- 2020/11/03 00:00 [received]
PHST- 2021/01/11 00:00 [revised]
PHST- 2021/01/31 00:00 [accepted]
PHST- 2021/02/21 06:00 [pubmed]
PHST- 2021/03/24 06:00 [medline]
PHST- 2021/02/20 20:14 [entrez]
AID - S0147-6513(21)00133-0 [pii]
AID - 10.1016/j.ecoenv.2021.112022 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2021 Apr 15;213:112022. doi: 
      10.1016/j.ecoenv.2021.112022. Epub 2021 Feb 18.