PMID- 3361188
OWN - NLM
STAT- MEDLINE
DCOM- 19880608
LR  - 20131121
IS  - 0300-9165 (Print)
IS  - 0300-9165 (Linking)
VI  - 40
IP  - 3
DP  - 1988 Mar
TI  - [Pregnancy in patients with chronic glomerulonephritis].
PG  - 365-72
AB  - This study was carried out to clarify the effect of pregnancy on chronic 
      glomerulonephritis (CGN). Fifteen patients with CGN diagnosed by renal biopsy 
      were studied throughout 17 pregnancies. The following criteria were adopted: 1) 
      Creatinine clearance (Ccr) over 70 ml/min and serum creatinine (s-Cr) 1.2 mg/dl 
      or less. 2) Blood pressure lower than 140/90 mmHg when not receiving any 
      medicine. 3) No evidence of active progress of nephropathy. In two patients 
      excluded from the criteria, renal function was adversely affected, but there was 
      no evidence that pregnancy affected the natural course of the underlying renal 
      disease. In the patients to which the criteria were applied, the outcome of 
      pregnancy and renal function were good. In conclusion, we recognized that there 
      was no relationship between the body weight of the newborn and maternal serum 
      albumin but that there was a significant correlation between serum uric acid and 
      body weight (r = -0.67). These results show that serum uric acid is a useful 
      indicator of placental dysfunction and fetal growth. In the patients with 
      preeclampsia, the serum uric acid concentration was higher than in the CGN group 
      (8.95 +/- 2.58 mg/dl vs 5.88 +/- 1.49 mg/dl: Scheffe method p less than 0.001). 
      There was no significant difference between the CGN and normal control (5.88 +/- 
      1.49 mg/dl vs 4.51 +/- 0.68: Scheffe method p less than 0.1). Uric acid serves to 
      distinguish CGN and preeclampsia.
FAU - Yoshida, A
AU  - Yoshida A
AD  - Third Department of Internal Medicine, Nagoya City University Medical School.
FAU - Morozumi, K
AU  - Morozumi K
FAU - Yagami, Y
AU  - Yagami Y
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Sanka Fujinka Gakkai Zasshi
JT  - Nihon Sanka Fujinka Gakkai zasshi
JID - 7505749
RN  - 0 (Serum Albumin)
RN  - 268B43MJ25 (Uric Acid)
RN  - AYI8EX34EU (Creatinine)
SB  - IM
MH  - Adult
MH  - Blood Urea Nitrogen
MH  - Chronic Disease
MH  - Creatinine/urine
MH  - Female
MH  - Glomerulonephritis/*physiopathology
MH  - Humans
MH  - Kidney Function Tests
MH  - Pregnancy
MH  - Pregnancy Complications/*physiopathology
MH  - Serum Albumin/analysis
MH  - Uric Acid/urine
EDAT- 1988/03/01 00:00
MHDA- 1988/03/01 00:01
CRDT- 1988/03/01 00:00
PHST- 1988/03/01 00:00 [pubmed]
PHST- 1988/03/01 00:01 [medline]
PHST- 1988/03/01 00:00 [entrez]
PST - ppublish
SO  - Nihon Sanka Fujinka Gakkai Zasshi. 1988 Mar;40(3):365-72.