PMID- 33617087
OWN - NLM
STAT- MEDLINE
DCOM- 20220418
LR  - 20221003
IS  - 1554-527X (Electronic)
IS  - 0736-0266 (Print)
IS  - 0736-0266 (Linking)
VI  - 39
IP  - 10
DP  - 2021 Oct
TI  - Minimal clinically important differences in SF-36 global score: Current value in 
      orthopedic oncology.
PG  - 2116-2123
LID - 10.1002/jor.24944 [doi]
AB  - The SF-36 is widely used to evaluate the health-related quality of life (HRQoL) 
      of patients with musculoskeletal tumors. Instead of typical methods, calculating 
      the SF-36 Global Score has recently become an increasingly common reporting 
      approach. However, numerical changes lack clear clinical relevance. The minimal 
      clinically important difference (MCID) is useful for interpreting changes in 
      functional scores by defining the smallest change patients may perceive as 
      clinically meaningful. The aim of this study is to determine the MCID of the 
      SF-36 Global Score in orthopedic oncology patients, which has not been reported 
      to date. Three-hundred ten patients who underwent surgery and completed two 
      surveys during postoperative follow-up were reviewed. The two most common methods 
      for calculating the SF-36 Global Score were used: (1) anchor-based methods and 
      receiver operating characteristic analysis based on one-half of the SD of change 
      score and standard error of measurement at baseline and; (2) distribution-based 
      methods. Using anchor-based methods, the MCIDs of SF-36 Global Scores #1 and #2 
      were 2.7 (area under the curve [AUC] = 0.85) and 2.5 (AUC = 0.79) for 
      improvement, and -1.5 (AUC = 0.81) and -0.6 (AUC = 0.83) for deterioration, 
      respectively. Using distribution-based methods, the MCIDs of SF-36 Global Scores 
      #1 and #2 were 4.1 and 4.4 by half SD, and 4.1 and 4.5 by standard error of 
      measurement, respectively. Our findings provide benchmark values, which can serve 
      as a reference for future studies in musculoskeletal tumor patients using the 
      SF-36 Global Score as a single measure for HRQoL.
CI  - (c) 2020 Orthopaedic Research Society. Published by Wiley Periodicals LLC.
FAU - Ogura, Koichi
AU  - Ogura K
AD  - Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer 
      Center, New York, New York, USA.
FAU - Bartelstein, Meredith K
AU  - Bartelstein MK
AD  - Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer 
      Center, New York, New York, USA.
FAU - Yakoub, Mohamed A
AU  - Yakoub MA
AD  - Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer 
      Center, New York, New York, USA.
FAU - Nikolic, Zarko
AU  - Nikolic Z
AD  - Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer 
      Center, New York, New York, USA.
FAU - Boland, Patrick J
AU  - Boland PJ
AD  - Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer 
      Center, New York, New York, USA.
FAU - Healey, John H
AU  - Healey JH
AUID- ORCID: 0000-0002-0802-1186
AD  - Department of Surgery, Orthopaedic Service, Memorial Sloan Kettering Cancer 
      Center, New York, New York, USA.
LA  - eng
GR  - P30 CA008748/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20201220
PL  - United States
TA  - J Orthop Res
JT  - Journal of orthopaedic research : official publication of the Orthopaedic 
      Research Society
JID - 8404726
SB  - IM
MH  - Humans
MH  - Minimal Clinically Important Difference
MH  - *Neoplasms
MH  - *Orthopedics
MH  - Quality of Life
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
PMC - PMC9348556
MID - NIHMS1825741
OTO - NOTNLM
OT  - SF-36 Global Score
OT  - anchor-based method
OT  - distribution-based method
OT  - health-related quality of life (HRQoL)
OT  - minimal clinically important difference (MCID)
OT  - sarcoma
COIS- Competing interests The authors declare that they have no competing interests.
EDAT- 2021/02/23 06:00
MHDA- 2022/04/19 06:00
PMCR- 2022/10/01
CRDT- 2021/02/22 12:20
PHST- 2020/10/21 00:00 [revised]
PHST- 2020/06/18 00:00 [received]
PHST- 2020/12/03 00:00 [accepted]
PHST- 2021/02/23 06:00 [pubmed]
PHST- 2022/04/19 06:00 [medline]
PHST- 2021/02/22 12:20 [entrez]
PHST- 2022/10/01 00:00 [pmc-release]
AID - 10.1002/jor.24944 [doi]
PST - ppublish
SO  - J Orthop Res. 2021 Oct;39(10):2116-2123. doi: 10.1002/jor.24944. Epub 2020 Dec 
      20.