PMID- 33618070 OWN - NLM STAT- MEDLINE DCOM- 20210621 LR - 20210719 IS - 1876-2026 (Electronic) IS - 1876-2018 (Linking) VI - 58 DP - 2021 Apr TI - Enhancing attention and memory of individuals at clinical high risk for psychosis with mHealth technology. PG - 102587 LID - S1876-2018(21)00043-5 [pii] LID - 10.1016/j.ajp.2021.102587 [doi] AB - BACKGROUND: Cognitive impairment has adverse impact on the social and role functions of those at clinical high risk for psychosis and it has become an important target for intervention. Mobile health applications are user-friendly, real-time, personalized and portable in administering cognitive training and have promising application prospects in the field of mental health. METHODS: Eighty CHR subjects were randomized into an intervention group and a control group. CHR subjects of the intervention group performed attention and memory training via a Specific Memory Attention Resource and Training (SMART) application in their smart phones for 10 min per day, five days per week for three months. Both groups were followed up for three months. At baseline and follow-up phases, cognitive function was measured using the MATRICS Consensus Cognitive Battery (MCCB). In the follow-up, the intervention group completed the Mobile Application Rating Scale (MARS) to provide feedback to improve SMART. RESULTS: There is a significant group by time interaction effect in the Attention/Vigilance domain, which is significantly better in the intervention group than in the control group at 3- month follow-up. The improvement in Attention/Vigilance in the intervention group is significantly related to the amount of cognitive training time. Global Assessment of Function (GAF) reduction rate at baseline could predict the improvement of Attention/Vigilance. MARS results indicate that CHR subjects were receptive of SMART. CONCLUSION: Mobile technology can be applied to improve cognitive function of CHR individuals, especially in the Attention/Vigilance domain. CI - Copyright (c) 2021 Elsevier B.V. All rights reserved. FAU - Li, Huijun AU - Li H AD - Florida A&M University, 501 Orr Drive, Psychology Department, United States. Electronic address: Huijun.li@famu.edu. FAU - Yang, Shuwen AU - Yang S AD - Shanghai Mental Health Center, 600 Wanping Nan Road, Shanghai, China. Electronic address: yangshuwen95@163.com. FAU - Chi, Hongmei AU - Chi H AD - Florida A&M University, 501 Orr Drive, Psychology Department, United States. Electronic address: Hongmei.chi@famu.edu. FAU - Xu, Lihua AU - Xu L AD - Shanghai Mental Health Center, 600 Wanping Nan Road, Shanghai, China. Electronic address: mas_xulihua2008@163.com. FAU - Zhang, Tianghong AU - Zhang T AD - Shanghai Mental Health Center, 600 Wanping Nan Road, Shanghai, China. Electronic address: zhang_tianhong@126.com. FAU - Singleton, Gwendolyn AU - Singleton G AD - Florida A&M University, 501 Orr Drive, Psychology Department, United States. Electronic address: Gwendolyn.singleton@famu.edu. FAU - Tang, Yingying AU - Tang Y AD - Shanghai Mental Health Center, 600 Wanping Nan Road, Shanghai, China. Electronic address: yytang0522@gmail.com. FAU - Stone, William S AU - Stone WS AD - Beth Israel Deaconess Medical Center, 75 Fenwood Road, Boston, 02115, United States. Electronic address: wstone@bidmc.harvard.edu. FAU - Wang, Jijun AU - Wang J AD - Shanghai Mental Health Center, 600 Wanping Nan Road, Shanghai, China. Electronic address: jijunwang27@163.com. LA - eng GR - R01 MH111448/MH/NIMH NIH HHS/United States GR - R21 MH113674/MH/NIMH NIH HHS/United States PT - Journal Article PT - Randomized Controlled Trial DEP - 20210211 PL - Netherlands TA - Asian J Psychiatr JT - Asian journal of psychiatry JID - 101517820 SB - IM MH - Attention MH - Humans MH - Memory MH - *Psychotic Disorders/therapy MH - Technology MH - *Telemedicine OTO - NOTNLM OT - Attention OT - Clinical high risk OT - Memory cognitive function OT - Mobile health application EDAT- 2021/02/23 06:00 MHDA- 2021/06/22 06:00 CRDT- 2021/02/22 20:11 PHST- 2020/10/08 00:00 [received] PHST- 2021/01/25 00:00 [revised] PHST- 2021/01/27 00:00 [accepted] PHST- 2021/02/23 06:00 [pubmed] PHST- 2021/06/22 06:00 [medline] PHST- 2021/02/22 20:11 [entrez] AID - S1876-2018(21)00043-5 [pii] AID - 10.1016/j.ajp.2021.102587 [doi] PST - ppublish SO - Asian J Psychiatr. 2021 Apr;58:102587. doi: 10.1016/j.ajp.2021.102587. Epub 2021 Feb 11.