PMID- 33619633
OWN - NLM
STAT- MEDLINE
DCOM- 20210819
LR  - 20220218
IS  - 1436-3771 (Electronic)
IS  - 1432-6981 (Print)
IS  - 1432-6981 (Linking)
VI  - 25
IP  - 9
DP  - 2021 Sep
TI  - Dental and periodontal disease in patients with inflammatory bowel disease.
PG  - 5273-5280
LID - 10.1007/s00784-021-03835-6 [doi]
AB  - OBJECTIVES: Although bowel symptoms are often predominant, inflammatory bowel 
      disease (IBD) patients can have several oral manifestations. The aim of this 
      study was to investigate the prevalence of dental caries and periodontal disease 
      in patients with Crohn's disease (CD) and ulcerative colitis (UC) compared to an 
      age and gender-matched control group of patients without IBD. MATERIAL AND 
      METHODS: The DMFT (Decayed, Missing, Filled Teeth) scores and the DPSI (Dutch 
      Periodontal Screening Index) of 229 IBD patients were retrieved from the 
      electronic health record patient database axiUm at the Academic Centre for 
      Dentistry Amsterdam (ACTA) and were compared to the DMFT scores and DPSI from age 
      and gender-matched non-IBD patients from the same database. RESULTS: The total 
      DMFT index was significantly higher in the IBD group compared to the control 
      group. When CD and UC were analyzed separately, a statistically significant 
      increased DMFT index was observed in CD patients but not in UC patients. The DPSI 
      did not differ significantly between the IBD and non-IBD groups for each of the 
      sextants. However, in every sextant, IBD patients were more frequently edentulous 
      compared to the control patients. CONCLUSION: CD patients have significantly more 
      dental health problems compared to a control group. Periodontal disease did not 
      differ significantly between IBD and non-IBD groups as determined by the DPSI. 
      CLINICAL RELEVANCE: It is important that IBD patients and physicians are 
      instructed about the correlation between their disease and oral health problems. 
      Strict oral hygiene and preventive dental care such as more frequent checkups 
      should be emphasized by dental clinicians.
CI  - (c) 2021. The Author(s).
FAU - Tan, Christopher X W
AU  - Tan CXW
AUID- ORCID: 0000-0002-0819-0238
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam University 
      Medical Centre/Academic Centre for Dentistry Amsterdam (ACTA), PO Box 7057, 1007 
      MB, Amsterdam, The Netherlands. c.tan@amsterdamumc.nl.
FAU - Brand, Henk S
AU  - Brand HS
AD  - Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), 
      Amsterdam, The Netherlands.
FAU - Kalender, Bilgin
AU  - Kalender B
AD  - Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam (ACTA), 
      Amsterdam, The Netherlands.
FAU - De Boer, Nanne K H
AU  - De Boer NKH
AD  - Department of Gastroenterology and Hepatology, Amsterdam University Medical 
      Centre, VU University, AGEM Research Institute, Amsterdam, The Netherlands.
FAU - Forouzanfar, Tymour
AU  - Forouzanfar T
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam University 
      Medical Centre/Academic Centre for Dentistry Amsterdam (ACTA), PO Box 7057, 1007 
      MB, Amsterdam, The Netherlands.
FAU - de Visscher, Jan G A M
AU  - de Visscher JGAM
AD  - Department of Oral and Maxillofacial Surgery/Oral Pathology, Amsterdam University 
      Medical Centre/Academic Centre for Dentistry Amsterdam (ACTA), PO Box 7057, 1007 
      MB, Amsterdam, The Netherlands.
LA  - eng
PT  - Journal Article
DEP - 20210223
PL  - Germany
TA  - Clin Oral Investig
JT  - Clinical oral investigations
JID - 9707115
MH  - *Colitis, Ulcerative/complications/epidemiology
MH  - *Dental Caries/epidemiology
MH  - Humans
MH  - *Inflammatory Bowel Diseases/complications/epidemiology
MH  - *Periodontal Diseases/complications/epidemiology
MH  - Periodontal Index
PMC - PMC8370899
OTO - NOTNLM
OT  - Crohn's disease
OT  - DMFT (Decayed
OT  - DPSI (Dutch Periodontal Screening Index)
OT  - Filled Teeth)
OT  - Inflammatory bowel disease
OT  - Missing
OT  - Oral health
OT  - Ulcerative colitis
COIS- N.K.H. de Boer served as a speaker for AbbVie and MSD and as a consultant and/or 
      principal investigator for TEVA Pharma VB and Takeda. He received (unrestricted) 
      research funding from MLDS, TEVA Pharma VB, and Takeda, all outside the submitted 
      work. All other authors have nothing to declare.
EDAT- 2021/02/24 06:00
MHDA- 2021/08/20 06:00
PMCR- 2021/02/23
CRDT- 2021/02/23 06:16
PHST- 2020/09/23 00:00 [received]
PHST- 2021/02/08 00:00 [accepted]
PHST- 2021/02/24 06:00 [pubmed]
PHST- 2021/08/20 06:00 [medline]
PHST- 2021/02/23 06:16 [entrez]
PHST- 2021/02/23 00:00 [pmc-release]
AID - 10.1007/s00784-021-03835-6 [pii]
AID - 3835 [pii]
AID - 10.1007/s00784-021-03835-6 [doi]
PST - ppublish
SO  - Clin Oral Investig. 2021 Sep;25(9):5273-5280. doi: 10.1007/s00784-021-03835-6. 
      Epub 2021 Feb 23.