PMID- 33625678 OWN - NLM STAT- MEDLINE DCOM- 20211015 LR - 20211015 IS - 2038-3312 (Electronic) IS - 2038-131X (Linking) VI - 73 IP - 2 DP - 2021 Apr TI - Total upper transversal hepatectomy with outflow reconstruction for advanced mass-forming cholangiocarcinoma. PG - 769-773 LID - 10.1007/s13304-020-00946-9 [doi] AB - We describe a complex case of extended hepatectomy with venous outflow reconstruction for the treatment of advanced mass-forming cholangiocarcinoma (MFCCC) invading the three main hepatic veins (HVs). A 50-year-old woman who received a diagnosis of MFCCC and judged unresectable, was referred to our hospital. After multidisciplinary team evaluation, the patient underwent abdominal computed tomography, gadoxetic acid-enhanced magnetic resonance imaging, and fluorodeoxyglucose positron emission tomography. The radiological examinations showed a large mass located in S4s-8 and S1, in contact with the right hepatic vein (RHV), the inferior right hepatic vein, the anterior wall of the inferior vena cava (IVC), infiltrating the middle and left hepatic veins (MHV, LHV). Several communicating veins between the RHV, MHV and LHV were detected. The case was further investigated, and the surgical strategy planned by means of using three-dimensional simulation software. A total upper transversal hepatectomy with resection of the main HVs and outflow reconstruction was performed. The outflow of the remnant liver was restored performing a vascular anastomosis between the parenchymal stump of the RHV and the IVC. Meticulous review of pre-operative imaging techniques with three-dimensional simulation of hepatectomy together with advanced use of intra-operative ultrasound allowed us to offer the chance of cure to a patient otherwise considered unresectable. FAU - Gentile, Damiano AU - Gentile D AD - Division of Hepatobiliary and General Surgery, Department of Surgery, Humanitas University, Humanitas Clinical and Research Center - IRCCS, Via Manzoni, 56, 20089, Rozzano, Milano, Italy. FAU - Donadon, Matteo AU - Donadon M AD - Division of Hepatobiliary and General Surgery, Department of Surgery, Humanitas University, Humanitas Clinical and Research Center - IRCCS, Via Manzoni, 56, 20089, Rozzano, Milano, Italy. AD - Department of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy. FAU - Civilini, Efrem AU - Civilini E AD - Department of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy. AD - Department of Vascular Surgery, Humanitas Clinical and Research Center - IRCCS, Rozzano, Milan, Italy. FAU - Torzilli, Guido AU - Torzilli G AUID- ORCID: 0000-0001-5798-5021 AD - Division of Hepatobiliary and General Surgery, Department of Surgery, Humanitas University, Humanitas Clinical and Research Center - IRCCS, Via Manzoni, 56, 20089, Rozzano, Milano, Italy. guido.torzilli@hunimed.eu. AD - Department of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy. guido.torzilli@hunimed.eu. LA - eng PT - Case Reports PT - Journal Article DEP - 20210224 PL - Italy TA - Updates Surg JT - Updates in surgery JID - 101539818 SB - IM MH - *Bile Duct Neoplasms/diagnostic imaging/surgery MH - Bile Ducts, Intrahepatic/diagnostic imaging/surgery MH - *Cholangiocarcinoma/diagnostic imaging/surgery MH - Female MH - Hepatectomy MH - Hepatic Veins/diagnostic imaging/surgery MH - Humans MH - *Liver Neoplasms/diagnostic imaging/surgery MH - Middle Aged MH - Vena Cava, Inferior/diagnostic imaging/surgery OTO - NOTNLM OT - Cholangiocarcinoma OT - Hepatectomy OT - Liver neoplasms OT - Surgery OT - Vascular resection EDAT- 2021/02/25 06:00 MHDA- 2021/10/16 06:00 CRDT- 2021/02/24 12:14 PHST- 2020/07/03 00:00 [received] PHST- 2020/12/08 00:00 [accepted] PHST- 2021/02/25 06:00 [pubmed] PHST- 2021/10/16 06:00 [medline] PHST- 2021/02/24 12:14 [entrez] AID - 10.1007/s13304-020-00946-9 [pii] AID - 10.1007/s13304-020-00946-9 [doi] PST - ppublish SO - Updates Surg. 2021 Apr;73(2):769-773. doi: 10.1007/s13304-020-00946-9. Epub 2021 Feb 24.