PMID- 33631733
OWN - NLM
STAT- MEDLINE
DCOM- 20210802
LR  - 20220118
IS  - 1361-6560 (Electronic)
IS  - 0031-9155 (Linking)
VI  - 66
IP  - 6
DP  - 2021 Mar 17
TI  - Four-dimensional inverse-geometry computed tomography: a preliminary study.
PG  - 065028
LID - 10.1088/1361-6560/abe9f8 [doi]
AB  - This study introduces and evaluates respiratory-correlated four-dimensional (4D) 
      inverse geometry computed tomography (IGCT). The projection data of the IGCT were 
      acquired in a single gantry rotation over 120 s. Three virtual phantoms-static 
      Defrise, 4D Shepp-Logan, and 4D extended cardiac-torso (XCAT)-were used to obtain 
      projection data for the IGCT and cone-beam computed tomography (CBCT). The 
      projection acquisition parameters were determined to eliminate vacancies in the 
      Radon space for an accurate rebinning process. Phase-based sorting was conducted 
      within 10 phase bins, and the sorted projection data were binned into a cone beam 
      geometry. Finally, Feldkamp-Davis-Kress reconstruction was conducted 
      independently at each phase. The reconstructed images were compared using the 
      structural similarity index measure (SSIM) and root mean square error (RMSE). The 
      vertical profile of the Defrise reconstruction image was uniform, and the cone 
      beam artefact was reduced in the IGCT image. Under an ideal projection 
      acquisition condition, the mean coronal plane SSIMs of the Shepp-Logan and 4D 
      XCAT phantoms were 0.899 and 0.706, respectively, which were higher than those of 
      the CBCT (0.784 and 0.623, respectively). Similarly, the mean RMSEs of the 
      coronal plane IGCT (0.036 and 0.158) exhibited an improvement over those of the 
      CBCT (0.165 and 0.261, respectively). The mean standard deviations of the SSIM 
      and RMSE were lower for IGCT than for CBCT. In particular, the SSIM and RMSE of 
      the sagittal and coronal planes of the Shepp-Logan IGCT images were stable in all 
      phase bins; however, those of the CBCT changed depending on the phase bins. Poor 
      image quality was observed for IGCT under inappropriate conditions. This was 
      caused by a vacancy in the Radon space, owing to an inappropriate scan setting. 
      Overall, the proposed 4D IGCT exhibited better image quality than conventional 
      CBCT.
FAU - Kim, Kyeong-Hyeon
AU  - Kim KH
AD  - Department of Biomedical Engineering, Department of Biomedicine and Health 
      Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic 
      of Korea.
AD  - Research Institute of Biomedical Engineering, College of Medicine, The Catholic 
      University of Korea, Seoul, Republic of Korea.
FAU - Shin, Dong-Seok
AU  - Shin DS
AD  - Department of Biomedical Engineering, Department of Biomedicine and Health 
      Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic 
      of Korea.
AD  - Research Institute of Biomedical Engineering, College of Medicine, The Catholic 
      University of Korea, Seoul, Republic of Korea.
FAU - Kang, Sang-Won
AU  - Kang SW
AD  - Department of Biomedical Engineering, Department of Biomedicine and Health 
      Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic 
      of Korea.
AD  - Research Institute of Biomedical Engineering, College of Medicine, The Catholic 
      University of Korea, Seoul, Republic of Korea.
FAU - Kang, Seong-Hee
AU  - Kang SH
AD  - Department of Radiation Oncology, Seoul National University Bundang Hospital, 
      Bundang, Gyeonggi-do, Republic of Korea.
FAU - Kim, Tae-Ho
AU  - Kim TH
AD  - Proton Therapy Center, National Cancer Center, Goyang, Gyeonggi-do, Republic of 
      Korea.
FAU - Chung, Jin-Beom
AU  - Chung JB
AD  - Department of Radiation Oncology, Seoul National University Bundang Hospital, 
      Bundang, Gyeonggi-do, Republic of Korea.
FAU - Suh, Tae Suk
AU  - Suh TS
AD  - Department of Biomedical Engineering, Department of Biomedicine and Health 
      Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic 
      of Korea.
AD  - Research Institute of Biomedical Engineering, College of Medicine, The Catholic 
      University of Korea, Seoul, Republic of Korea.
FAU - Kim, Dong-Su
AU  - Kim DS
AD  - Department of Biomedical Engineering, Department of Biomedicine and Health 
      Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic 
      of Korea.
AD  - Research Institute of Biomedical Engineering, College of Medicine, The Catholic 
      University of Korea, Seoul, Republic of Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210317
PL  - England
TA  - Phys Med Biol
JT  - Physics in medicine and biology
JID - 0401220
SB  - IM
MH  - Algorithms
MH  - Artifacts
MH  - Computer Simulation
MH  - Cone-Beam Computed Tomography/*methods
MH  - Four-Dimensional Computed Tomography/*methods
MH  - Humans
MH  - Image Processing, Computer-Assisted/*methods
MH  - Lung Neoplasms/diagnostic imaging/radiotherapy
MH  - Motion
MH  - Phantoms, Imaging
MH  - Radiotherapy Planning, Computer-Assisted
EDAT- 2021/02/26 06:00
MHDA- 2021/08/03 06:00
CRDT- 2021/02/25 20:18
PHST- 2021/02/26 06:00 [pubmed]
PHST- 2021/08/03 06:00 [medline]
PHST- 2021/02/25 20:18 [entrez]
AID - 10.1088/1361-6560/abe9f8 [doi]
PST - epublish
SO  - Phys Med Biol. 2021 Mar 17;66(6):065028. doi: 10.1088/1361-6560/abe9f8.