PMID- 33641089 OWN - NLM STAT- MEDLINE DCOM- 20211115 LR - 20211115 IS - 1559-0720 (Electronic) IS - 0163-4984 (Linking) VI - 200 IP - 1 DP - 2022 Jan TI - Concentration of Potentially Toxic Elements in Vegetable Oils and Health Risk Assessment: a Systematic Review and Meta-analysis. PG - 437-446 LID - 10.1007/s12011-021-02645-x [doi] AB - The present study evaluates the concentration of potentially toxic elements (PTEs), including Pb, Cd, As, Fe, Zn, Cu, and Ni, in vegetable oils through a meta-analytic approach. The published studies in relation to the concentrations of PTEs in vegetable oils were retrieved from major international databases such as PubMed, Scopus, Web of Science, and Embase followed by meta-analysis. Moreover, the health risk assessment was evaluated using total target hazard quotient (TTHQ) by a Monte Carlo simulation (MCS) model. According to the results of 51 articles included among 958 retrieved studies, the concentrations of the PTEs were as follows: Cd approximately As (0.110 mg/kg) > Pb (0.086 mg/kg) in cottonseed, canola, and olive oil and Fe (12.964 mg/kg) > Zn (1.044 mg/kg) > Ni (0.893 mg/kg) > Cu (0.264 mg/kg) in cottonseed, olive, and soybean for trace elementals, respectively. Based on the continent type, the higher concentration of Cd, As, and Pb was related to PAHO (American region) and AFRO (African region), and the higher concentrations of Fe, Zn, Cu, and Ni were observed in WPRO (Western Pacific Region), EMRO (Eastern Mediterranean Region), and AFRO. On the other hand, non-carcinogenic health risk assessment of the PTEs indicated that there was a different risk pattern in various countries, and the TTHQ level in adult groups was lower than 1. It can be concluded that the consumption of vegetable oils is safe and does not pose risk to the health of consumers. CI - (c) 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature. FAU - Ghane, Elaheh Talebi AU - Ghane ET AUID- ORCID: 0000-0003-2610-1419 AD - Hamadan University of Medical Sciences, Hamadan, Iran. FAU - Poormohammadi, Ali AU - Poormohammadi A AUID- ORCID: 0000-0002-3997-326X AD - Center of Excellence for Occupational Health, Research Center for Health Sciences, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran. FAU - Khazaei, Salman AU - Khazaei S AUID- ORCID: 0000-0001-5918-2310 AD - Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran. FAU - Mehri, Fereshteh AU - Mehri F AUID- ORCID: 0000-0003-0106-245X AD - Nutrition Health Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. freshteh_mehri@yahoo.com. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review PT - Systematic Review DEP - 20210227 PL - United States TA - Biol Trace Elem Res JT - Biological trace element research JID - 7911509 RN - 0 (Metals, Heavy) RN - 0 (Plant Oils) RN - 0 (Soil Pollutants) SB - IM MH - Environmental Monitoring MH - *Metals, Heavy/analysis/toxicity MH - Plant Oils MH - Risk Assessment MH - *Soil Pollutants/analysis OTO - NOTNLM OT - Health risk assessment OT - Meta-analysis OT - PTEs OT - Systematic review OT - Vegetable oils EDAT- 2021/03/01 06:00 MHDA- 2021/11/16 06:00 CRDT- 2021/02/28 20:40 PHST- 2021/02/05 00:00 [received] PHST- 2021/02/16 00:00 [accepted] PHST- 2021/03/01 06:00 [pubmed] PHST- 2021/11/16 06:00 [medline] PHST- 2021/02/28 20:40 [entrez] AID - 10.1007/s12011-021-02645-x [pii] AID - 10.1007/s12011-021-02645-x [doi] PST - ppublish SO - Biol Trace Elem Res. 2022 Jan;200(1):437-446. doi: 10.1007/s12011-021-02645-x. Epub 2021 Feb 27.