PMID- 33642170
OWN - NLM
STAT- MEDLINE
DCOM- 20220131
LR  - 20220131
IS  - 1532-8422 (Electronic)
IS  - 1053-0770 (Linking)
VI  - 36
IP  - 2
DP  - 2022 Feb
TI  - ECPella: Concept, Physiology and Clinical Applications.
PG  - 557-566
LID - S1053-0770(21)00093-8 [pii]
LID - 10.1053/j.jvca.2021.01.056 [doi]
AB  - Addition of Impella on top of venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO) has gained wide interest as it might portend improved outcomes in 
      patients with cardiogenic shock. This has been consistently reported in 
      retrospective propensity-matched studies, case series, and meta-analyses. The 
      pathophysiologic background is based on the mitigation of ECMO-related side 
      effects and the additive benefit of myocardial unloading. In this perspective, 
      thorough knowledge of these mechanisms is required to optimize the management of 
      mechanical circulatory support with this approach and introduce best practices, 
      as the interplay between the two devices and the implantation-explantation 
      strategies are key for success.
CI  - Copyright (c) 2021 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Meani, P
AU  - Meani P
AD  - Department of Cardiothoracic and Vascular Anesthesia and Intensive Care Unit 
      (ICU), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico 
      San Donato, San Donato Milanese, Milan, Italy; ECLS Centrum, Cardio-Thoracic 
      Surgery Department, Heart & Vascular Centre, Maastricht University Medical 
      Centre, Maastricht (MUMC), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands. 
      Electronic address: paolo.meani@mumc.nl.
FAU - Lorusso, R
AU  - Lorusso R
AD  - ECLS Centrum, Cardio-Thoracic Surgery Department, Heart & Vascular Centre, 
      Maastricht University Medical Centre, Maastricht (MUMC), P. Debyelaan 25, 6229 
      HX, Maastricht, The Netherlands.
FAU - Pappalardo, F
AU  - Pappalardo F
AD  - Department of Anaesthesia and Intensive Care, IRCCS ISMETT, UPMC Italy, Palermo, 
      Italy.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210206
PL  - United States
TA  - J Cardiothorac Vasc Anesth
JT  - Journal of cardiothoracic and vascular anesthesia
JID - 9110208
SB  - IM
MH  - Device Removal
MH  - *Extracorporeal Membrane Oxygenation
MH  - *Heart-Assist Devices
MH  - Humans
MH  - Retrospective Studies
MH  - Shock, Cardiogenic/therapy
OTO - NOTNLM
OT  - VA ECLS
OT  - cardiogenic shock
OT  - ecpella
OT  - impella
OT  - physiology
EDAT- 2021/03/02 06:00
MHDA- 2022/02/01 06:00
CRDT- 2021/03/01 05:31
PHST- 2020/11/11 00:00 [received]
PHST- 2021/01/24 00:00 [revised]
PHST- 2021/01/29 00:00 [accepted]
PHST- 2021/03/02 06:00 [pubmed]
PHST- 2022/02/01 06:00 [medline]
PHST- 2021/03/01 05:31 [entrez]
AID - S1053-0770(21)00093-8 [pii]
AID - 10.1053/j.jvca.2021.01.056 [doi]
PST - ppublish
SO  - J Cardiothorac Vasc Anesth. 2022 Feb;36(2):557-566. doi: 
      10.1053/j.jvca.2021.01.056. Epub 2021 Feb 6.