PMID- 33647066
OWN - NLM
STAT- MEDLINE
DCOM- 20211013
LR  - 20221207
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 16
IP  - 3
DP  - 2021
TI  - On the joint role of non-Hispanic Black race/ethnicity and weight status in 
      predicting postmenopausal weight gain.
PG  - e0247821
LID - 10.1371/journal.pone.0247821 [doi]
LID - e0247821
AB  - OBJECTIVES: To determine how baseline weight status contributes to differences in 
      postmenopausal weight gain among non-Hispanic Blacks (NHBs) and non-Hispanic 
      Whites (NHWs). METHODS: Data were included from 70,750 NHW and NHB postmenopausal 
      women from the Women's Health Initiative Observational Study (WHI OS). Body Mass 
      Index (BMI) at baseline was used to classify women as having normal weight, 
      overweight, obese class I, obese class II or obese class III. Cox proportional 
      hazards was used to estimate the hazard of a 10% or more increase in weight from 
      baseline. RESULTS: In both crude and adjusted models, NHBs were more likely to 
      experience >/=10% weight gain than NHWs within the same category of baseline weight 
      status. Moreover, NHBs who were normal weight at baseline were most likely to 
      experience >/=10% weight gain in both crude and adjusted models. Age-stratified 
      results were consistent with overall findings. In all age categories, NHBs who 
      were normal weight at baseline were most likely to experience >/=10% weight gain. 
      Based on the results of adjusted models, the joint influence of NHB 
      race/ethnicity and weight status on risk of postmenopausal weight gain was both 
      sub-additive and sub-multiplicative. CONCLUSION: NHBs are more likely to 
      experience postmenopausal weight gain than NHWs, and the disparity in risk is 
      most pronounced among those who are normal weight at baseline. To address the 
      disparity in postmenopausal obesity, future studies should focus on identifying 
      and modifying factors that promote weight gain among normal weight NHBs.
FAU - Ford, Christopher N
AU  - Ford CN
AUID- ORCID: 0000-0001-6730-0436
AD  - Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, IL, 
      United States of America.
FAU - Chang, Shine
AU  - Chang S
AD  - Department of Epidemiology, University of Texas MD Anderson Cancer Center, 
      Houston, TX, United States of America.
FAU - Wood, Alexis C
AU  - Wood AC
AD  - USDA/ARS Children's Nutrition Research Center, Baylor College of Medicine, 
      Houston, TX, United States of America.
FAU - Manson, JoAnn E
AU  - Manson JE
AD  - Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 
      Boston, MA, United States of America.
FAU - Garcia, David O
AU  - Garcia DO
AUID- ORCID: 0000-0001-6669-9457
AD  - Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public 
      Health, University of Arizona, Tucson, AZ, United States of America.
FAU - Laroche, Helena
AU  - Laroche H
AUID- ORCID: 0000-0003-3708-5207
AD  - Center for Children's Healthy Lifestyles and Nutrition, Children's Mercy 
      Hospital, Kansas City and University of Missouri, Kansas City, MO, United States 
      of America.
FAU - Bird, Chloe E
AU  - Bird CE
AD  - RAND Corporation, Santa Monica, CA, United States of America.
FAU - Vitolins, Mara Z
AU  - Vitolins MZ
AD  - Department of Epidemiology and Prevention, Wake Forest School of Medicine, Wake 
      Forest, NC, United States of America.
LA  - eng
GR  - R25 CA057730/CA/NCI NIH HHS/United States
GR  - HHSN268201100004I/HL/NHLBI NIH HHS/United States
GR  - HHSN268201100046C/HL/NHLBI NIH HHS/United States
GR  - HHSN268201100003C/WH/WHI NIH HHS/United States
GR  - HHSN271201100004C/AG/NIA NIH HHS/United States
GR  - HHSN268201100002C/WH/WHI NIH HHS/United States
GR  - HHSN268201100003I/HL/NHLBI NIH HHS/United States
GR  - HHSN268201100002I/HL/NHLBI NIH HHS/United States
GR  - HHSN268201100004C/WH/WHI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20210301
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Aged
MH  - Black People
MH  - *Body Mass Index
MH  - Hispanic or Latino
MH  - Humans
MH  - Middle Aged
MH  - Postmenopause/*ethnology
MH  - Race Factors
MH  - United States
MH  - *Weight Gain
MH  - White People
PMC - PMC7920337
COIS- CEB is employed by the RAND Corporation. This does not alter our adherence to 
      PLOS ONE policies on sharing data and materials.
EDAT- 2021/03/02 06:00
MHDA- 2021/10/14 06:00
PMCR- 2021/03/01
CRDT- 2021/03/01 17:10
PHST- 2020/09/09 00:00 [received]
PHST- 2021/02/15 00:00 [accepted]
PHST- 2021/03/01 17:10 [entrez]
PHST- 2021/03/02 06:00 [pubmed]
PHST- 2021/10/14 06:00 [medline]
PHST- 2021/03/01 00:00 [pmc-release]
AID - PONE-D-20-26567 [pii]
AID - 10.1371/journal.pone.0247821 [doi]
PST - epublish
SO  - PLoS One. 2021 Mar 1;16(3):e0247821. doi: 10.1371/journal.pone.0247821. 
      eCollection 2021.