PMID- 3364749
OWN - NLM
STAT- MEDLINE
DCOM- 19880602
LR  - 20190903
IS  - 0340-2061 (Print)
IS  - 0340-2061 (Linking)
VI  - 177
IP  - 5
DP  - 1988
TI  - Dolichos biflorus agglutinin: a marker of the developing olfactory system in the 
      NMRI-mouse strain.
PG  - 459-64
AB  - The binding of horseradish peroxidase-labelled Dolichos biflorus agglutinin 
      (HRP-DBA) to the olfactory system of NMRI-mice was investigated histochemically 
      during the pre- and postnatal period. DBA bound with high affinity to a group of 
      olfactory receptor neurons of both the olfactory epithelium proper and the 
      vomeronasal organ from gestation days (g.d.) 14 and 15 onward respectively. 
      Furthermore, there was also extensive binding to axon bundles and to the 
      glomeruli of the main and accessory olfactory bulbs. In addition, DBA-binding was 
      observed in goblet cells and some glands of the nasal septum. From g.d. 17 onward 
      the number of DBA-positive neurons increased significantly and the glomeruli 
      within the olfactory bulbs became DBA-reactive for the first time. Concomitantly, 
      the endothelium of vessels within the olfactory epithelium's submucosa lost its 
      DBA-affinity, though the respiratory submucosal vessels still remained 
      DBA-positive. Possible interrelationships between DBA-affinity of blood vessel 
      endothelium and the neighbouring olfactory neurons are discussed.
FAU - Plendl, J
AU  - Plendl J
AD  - Gesellschaft fur Strahlen- und Umweltforschung, Munchen, Abteilung 
      Nuklearbiologie, Federal Republic of Germany.
FAU - Schmahl, W
AU  - Schmahl W
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Anat Embryol (Berl)
JT  - Anatomy and embryology
JID - 7505194
RN  - 0 (Lectins)
RN  - 0 (Plant Lectins)
RN  - 0 (dolichos biflorus agglutinin)
RN  - EC 3.2.1.18 (Neuraminidase)
SB  - IM
MH  - Animals
MH  - Animals, Newborn/growth & development/metabolism
MH  - Central Nervous System/*growth & development
MH  - Endothelium, Vascular/metabolism
MH  - *Lectins/metabolism
MH  - Mice
MH  - Mice, Inbred Strains/*growth & development/metabolism
MH  - Nasal Mucosa/metabolism
MH  - Neuraminidase/pharmacology
MH  - Nose/blood supply/cytology
MH  - Olfactory Pathways/*growth & development/metabolism
MH  - *Plant Lectins
EDAT- 1988/01/01 00:00
MHDA- 1988/01/01 00:01
CRDT- 1988/01/01 00:00
PHST- 1988/01/01 00:00 [pubmed]
PHST- 1988/01/01 00:01 [medline]
PHST- 1988/01/01 00:00 [entrez]
AID - 10.1007/BF00304744 [doi]
PST - ppublish
SO  - Anat Embryol (Berl). 1988;177(5):459-64. doi: 10.1007/BF00304744.