PMID- 33648512 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20231110 IS - 1477-7819 (Electronic) IS - 1477-7819 (Linking) VI - 19 IP - 1 DP - 2021 Mar 1 TI - Laparoscopic intragastric resection of gastric synovial sarcoma: report of the first ever case with video demonstration. PG - 65 LID - 10.1186/s12957-021-02172-y [doi] LID - 65 AB - BACKGROUND: Synovial sarcoma (SS) is a rare soft tissue tumor. Among different anatomical locations where it can be found, gastric localization is a very uncommon one. Based on soft tissue sarcoma guidelines, complete tumor excision is considered the main treatment approach. Depending on size and localization of the tumor, both wedge and major gastric resections have been performed in the past for the treatment of this condition. CASE PRESENTATION: We present the case of a 43-year-old woman who underwent a laparoscopic intragastric excision of a gastric 10-mm SS located nearby the esophagogastric junction. Pathology examination confirmed the presence of a SS. The resected specimen confirmed margin-free excision of a monophasic spindle cell neoplasm invading the submucosa and presenting the rearrangement of SS18 gene at fluorescence in situ hybridization (FISH). No adjuvant treatment was offered, and 18 months after surgery, the patient was alive and disease free. CONCLUSIONS: This represents the first case reported in literature of a laparoscopic intragastric resection for a gastric SS. This approach allowed to obtain a full thickness radical tumor resection with the advantages of minimally invasive and organ preserving surgery. FAU - Rivelli, Matteo AU - Rivelli M AD - Unit of General and Hepatobiliary Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Verona University, Verona, Italy. FAU - Fernandes, Eduardo AU - Fernandes E AD - Division of Minimally Invasive, General and Robotic Surgery, University of Illinois at Chicago, Chicago, USA. FAU - Conti, Cristian AU - Conti C AD - Unit of General and Hepatobiliary Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Verona University, Verona, Italy. FAU - Bernardoni, Laura AU - Bernardoni L AD - Digestive Endoscopy Unit, The Pancreas Institute, Verona University and Hospital Trust, Verona, Italy. FAU - Pecori, Sara AU - Pecori S AD - Pathological Anatomy Section, Department of Diagnostics and Public Health, Verona University and Hospital Trust, Verona, Italy. FAU - Cingarlini, Sara AU - Cingarlini S AD - Oncology Section, Department of Oncology, Verona University and Hospital Trust, Verona, Italy. FAU - Pedrazzani, Corrado AU - Pedrazzani C AUID- ORCID: 0000-0003-2431-6117 AD - Unit of General and Hepatobiliary Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Verona University, Verona, Italy. corrado.pedrazzani@univr.it. AD - Unit of General and Hepatobiliary Surgery, University Hospital "G.B. Rossi", Piazzale "L. Scuro" 10, 37134, Verona, Italy. corrado.pedrazzani@univr.it. LA - eng PT - Case Reports PT - Journal Article DEP - 20210301 PL - England TA - World J Surg Oncol JT - World journal of surgical oncology JID - 101170544 SB - IM MH - Adult MH - Female MH - Humans MH - In Situ Hybridization, Fluorescence MH - *Laparoscopy MH - Prognosis MH - *Sarcoma, Synovial/diagnostic imaging/surgery MH - *Stomach Neoplasms/surgery PMC - PMC7923835 OTO - NOTNLM OT - Gastric sarcoma OT - Intragastric resection OT - Laparoscopy OT - Organ-preserving surgery OT - Synovial sarcoma COIS- The authors declare no competing interests. EDAT- 2021/03/03 06:00 MHDA- 2021/05/15 06:00 PMCR- 2021/03/01 CRDT- 2021/03/02 05:43 PHST- 2020/12/22 00:00 [received] PHST- 2021/02/17 00:00 [accepted] PHST- 2021/03/02 05:43 [entrez] PHST- 2021/03/03 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] PHST- 2021/03/01 00:00 [pmc-release] AID - 10.1186/s12957-021-02172-y [pii] AID - 2172 [pii] AID - 10.1186/s12957-021-02172-y [doi] PST - epublish SO - World J Surg Oncol. 2021 Mar 1;19(1):65. doi: 10.1186/s12957-021-02172-y.