PMID- 33648778
OWN - NLM
STAT- MEDLINE
DCOM- 20211124
LR  - 20211124
IS  - 1768-3122 (Electronic)
IS  - 0248-8663 (Linking)
VI  - 42
IP  - 7
DP  - 2021 Jul
TI  - [Helicobacter pylori: When to look for an infection and treat it in adults?].
PG  - 482-491
LID - S0248-8663(20)30792-X [pii]
LID - 10.1016/j.revmed.2020.11.012 [doi]
AB  - Helicobacter pylori infection is acquired during childhood mainly within the 
      family. It causes active chronic gastritis associated with the development of 
      many digestive and extra digestive diseases. Its expression results from 
      interactions between the bacteria, the host and environmental factors modulating 
      the evolution of gastritis and acid secretion. The French recommendations for 
      research and treatment for curative or preventive purposes were updated in 2017. 
      These are indications with a high level of evidence for association and efficacy 
      of the eradication treatment: peptic ulcer, taking non-steroidal 
      anti-inflammatory drugs or aspirin with an ulcer history, gastric MALT lymphoma, 
      and localized resection of gastric cancer. The recommendations relate to other 
      diseases with a lower level of evidence: functional dyspepsia, risk factors for 
      gastric adenocarcinoma (family history of gastric cancer, Lynch syndrome, 
      pre-neoplastic lesions: atrophy, intestinal metaplasia, dysplasia), unexplained 
      iron deficiency anemia and vitamin B12 deficiency, immunological thrombocytopenic 
      purpura, bariatric surgery isolating part of the stomach. The diagnosis is made 
      by examining gastric biopsies or by non-invasive test depending on the clinical 
      situation. The 10-day triple therapies guided by the study of antibiotic 
      sensitivity (proton pump inhibitors (PPI), amoxicillin, clarithromycin or 
      levofloxacin) are recommended as first-line treatment because of the increase in 
      resistance, allowing the reduction of the duration of treatment, the number of 
      antibiotics and side effects. By default, probabilistic quadruple therapies of 14 
      days are possible and interchangeable (PPI with amoxicillin, clarithromycin, 
      metronidazole, or a combination of bismuth salt, tetracycline and metronidazole). 
      Eradication control is necessary.
CI  - Copyright (c) 2020 Societe Nationale Francaise de Medecine Interne (SNFMI). 
      Published by Elsevier Masson SAS. All rights reserved.
FAU - de Korwin, J-D
AU  - de Korwin JD
AD  - Universite de Lorraine, CHRU-Nancy, departement de medecine interne et 
      immunologie clinique-BPC, rue du Morvan, 54511 Vandoeuvre-Les-Nancy cedex, France. 
      Electronic address: jd.dekorwin@chru-nancy.fr.
LA  - fre
PT  - Journal Article
TT  - Helicobacter pylori : quand rechercher une infection et la traiter chez 
      l'adulte ?
DEP - 20210226
PL  - France
TA  - Rev Med Interne
JT  - La Revue de medecine interne
JID - 8101383
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Proton Pump Inhibitors)
RN  - 804826J2HU (Amoxicillin)
RN  - H1250JIK0A (Clarithromycin)
SB  - IM
MH  - Adult
MH  - Amoxicillin/therapeutic use
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Clarithromycin/therapeutic use
MH  - Drug Therapy, Combination
MH  - *Helicobacter Infections/complications/diagnosis/drug therapy
MH  - *Helicobacter pylori
MH  - Humans
MH  - Proton Pump Inhibitors/therapeutic use
OTO - NOTNLM
OT  - Antibiotiques
OT  - Chronic gastritis
OT  - Diagnosis
OT  - Diagnostic
OT  - Gastrite chronique
OT  - Helicobacter pylori
OT  - Traitement
OT  - Treatment
OT  - antibiotics
EDAT- 2021/03/03 06:00
MHDA- 2021/11/25 06:00
CRDT- 2021/03/02 05:49
PHST- 2020/06/27 00:00 [received]
PHST- 2020/11/15 00:00 [accepted]
PHST- 2021/03/03 06:00 [pubmed]
PHST- 2021/11/25 06:00 [medline]
PHST- 2021/03/02 05:49 [entrez]
AID - S0248-8663(20)30792-X [pii]
AID - 10.1016/j.revmed.2020.11.012 [doi]
PST - ppublish
SO  - Rev Med Interne. 2021 Jul;42(7):482-491. doi: 10.1016/j.revmed.2020.11.012. Epub 
      2021 Feb 26.