PMID- 33651465
OWN - NLM
STAT- MEDLINE
DCOM- 20211119
LR  - 20211119
IS  - 1759-7714 (Electronic)
IS  - 1759-7706 (Print)
IS  - 1759-7706 (Linking)
VI  - 12
IP  - 8
DP  - 2021 Apr
TI  - Endobronchial brachytherapy combined with surgical procedure for synchronous 
      multiple primary lung cancer: A case report.
PG  - 1252-1255
LID - 10.1111/1759-7714.13911 [doi]
AB  - The management of synchronous multiple primary lung cancer is a challenge. In 
      this report, we describe our experience in a patient with three synchronous 
      multiple cancers. The first lesion was completely surgically removed, the second 
      lesion received postoperative irradiation, and the third lesion was treated with 
      radiotherapy alone. Radiation therapies were performed using a combination of 
      external irradiation and endobronchial brachytherapy. Endobronchial brachytherapy 
      is an effective radiation therapy for endobronchial tumors owing to its advantage 
      of high-dose concentration. However, adverse events (AEs) such as hemoptysis or 
      severe bronchitis are a problem. Thus, we have developed an applicator to keep 
      the radioactive source in the center of the bronchial lumen. A total of 28 months 
      after treatment, the patient had not experienced any relapses or AEs. 
      Endobronchial brachytherapy using an applicator can be an alternative treatment 
      for cases in which surgery is expected to lead to pulmonary dysfunction.
CI  - (c) 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and 
      John Wiley & Sons Australia, Ltd.
FAU - Omori, Kazuki
AU  - Omori K
AD  - Department of Radiology, Mie University, Tsu, Japan.
FAU - Nomoto, Yoshihito
AU  - Nomoto Y
AUID- ORCID: 0000-0003-4063-3067
AD  - Department of Radiology, Mie University, Tsu, Japan.
FAU - Kawamura, Tomoko
AU  - Kawamura T
AD  - Department of Radiology, Mie University, Tsu, Japan.
FAU - Kubooka, Makiko
AU  - Kubooka M
AD  - Department of Radiology, Mie University, Tsu, Japan.
FAU - Kawaguchi, Koji
AU  - Kawaguchi K
AD  - Department of Thoracic Surgery, Mie University, Tsu, Japan.
FAU - Ii, Noriko
AU  - Ii N
AD  - Department of Radiation Oncology, Ise Red Cross Hospital, Ise, Japan.
FAU - Takada, Akinori
AU  - Takada A
AD  - Department of Radiology, Mie University, Tsu, Japan.
FAU - Toyomasu, Yutaka
AU  - Toyomasu Y
AD  - Department of Radiology, Mie University, Tsu, Japan.
FAU - Sakuma, Hajime
AU  - Sakuma H
AD  - Department of Radiology, Mie University, Tsu, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20210302
PL  - Singapore
TA  - Thorac Cancer
JT  - Thoracic cancer
JID - 101531441
SB  - IM
MH  - Aged
MH  - Brachytherapy/*methods
MH  - Bronchoscopy/*methods
MH  - Humans
MH  - Lung Neoplasms/*diagnostic imaging/pathology
MH  - Male
PMC - PMC8046068
OTO - NOTNLM
OT  - applicator
OT  - endobronchial brachytherapy
OT  - synchronous multiple primary lung cancer
COIS- The authors declare that there are no conflicts of interest.
EDAT- 2021/03/03 06:00
MHDA- 2021/11/20 06:00
PMCR- 2021/04/01
CRDT- 2021/03/02 12:17
PHST- 2021/02/12 00:00 [revised]
PHST- 2020/12/26 00:00 [received]
PHST- 2021/02/12 00:00 [accepted]
PHST- 2021/03/03 06:00 [pubmed]
PHST- 2021/11/20 06:00 [medline]
PHST- 2021/03/02 12:17 [entrez]
PHST- 2021/04/01 00:00 [pmc-release]
AID - TCA13911 [pii]
AID - 10.1111/1759-7714.13911 [doi]
PST - ppublish
SO  - Thorac Cancer. 2021 Apr;12(8):1252-1255. doi: 10.1111/1759-7714.13911. Epub 2021 
      Mar 2.