PMID- 33653867 OWN - NLM STAT- MEDLINE DCOM- 20210310 LR - 20210408 IS - 1757-790X (Electronic) IS - 1757-790X (Linking) VI - 14 IP - 3 DP - 2021 Mar 2 TI - Reactive arthritis after COVID-19. LID - 10.1136/bcr-2020-241375 [doi] LID - e241375 AB - A previously healthy 53-year-old man was hospitalised for 12 days due to COVID-19 with shortness of breath. A few days after discharge from hospital, the patient developed fever and severe pain in several joints in the lower extremities. The pain was so severe that the patient was unable to stand on his feet. Synovial fluid from the right-side knee contained a high number of polynuclear cells and a few mononuclear cells. Microscopy, culture and PCR tests for bacterial infection were all negative. Furthermore, the patient tested negative for rheumatoid factor, anti-cyclic citrullinated peptide and human leukocyte antigen (HLA)-B27. Thus, the condition was compatible with reactive arthritis. The condition improved markedly after a few days' treatment with non-steroid anti-inflammatory drugs and prednisolone. CI - (c) BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. FAU - Honge, Bo Langhoff AU - Honge BL AUID- ORCID: 0000-0001-9636-4519 AD - Department of Infectious Diseases, Aarhus Universitet, Aarhus, Denmark bohonge@gmail.com. FAU - Hermansen, Marie-Louise From AU - Hermansen MF AD - Department of Internal Medicine, Randers Regional Hospital, Randers, Midtjylland, Denmark. FAU - Storgaard, Merete AU - Storgaard M AD - Intensive Care, Aarhus Universitetshospital, Aarhus, Denmark. LA - eng PT - Case Reports PT - Journal Article DEP - 20210302 PL - England TA - BMJ Case Rep JT - BMJ case reports JID - 101526291 RN - 0 (Anti-Inflammatory Agents) RN - 0 (Anti-Inflammatory Agents, Non-Steroidal) RN - 0 (Autoantibodies) RN - 9PHQ9Y1OLM (Prednisolone) SB - IM MH - Anti-Inflammatory Agents/administration & dosage MH - Anti-Inflammatory Agents, Non-Steroidal/*administration & dosage MH - Arthralgia/diagnosis/etiology MH - *Arthritis/drug therapy/etiology/physiopathology MH - *Arthritis, Reactive/diagnosis/drug therapy/physiopathology/virology MH - Arthritis, Rheumatoid/diagnosis MH - Autoantibodies/analysis MH - *COVID-19/complications/physiopathology/therapy MH - Diagnosis, Differential MH - Humans MH - Knee Joint/diagnostic imaging MH - Lower Extremity/pathology MH - Male MH - Middle Aged MH - Prednisolone/*administration & dosage MH - Radiography/methods MH - *Synovial Fluid/cytology/immunology MH - Treatment Outcome PMC - PMC7929821 OTO - NOTNLM OT - COVID-19 OT - immunology OT - rheumatology COIS- Competing interests: None declared. EDAT- 2021/03/04 06:00 MHDA- 2021/03/11 06:00 PMCR- 2021/03/02 CRDT- 2021/03/03 05:38 PHST- 2021/03/03 05:38 [entrez] PHST- 2021/03/04 06:00 [pubmed] PHST- 2021/03/11 06:00 [medline] PHST- 2021/03/02 00:00 [pmc-release] AID - 14/3/e241375 [pii] AID - bcr-2020-241375 [pii] AID - 10.1136/bcr-2020-241375 [doi] PST - epublish SO - BMJ Case Rep. 2021 Mar 2;14(3):e241375. doi: 10.1136/bcr-2020-241375.