PMID- 33655029
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210305
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 9
IP  - 3
DP  - 2021 Mar
TI  - Lumen-apposing metal stent through the meshes of duodenal metal stents for 
      palliation of malignant jaundice.
PG  - E324-E330
LID - 10.1055/a-1333-1053 [doi]
AB  - Background and study aims  Endoscopic retrograde cholangiopancreatography (ERCP) 
      is the gold standard procedure for malignant jaundice palliation; however, it can 
      be challenging when a duodenal self-expandable metal stent (SEMS) is already in 
      place. Patients and methods  The primary aim of our study was to evaluate the 
      technical feasibility of the placement of a lumen apposing metal stent (LAMS) 
      through the mesh (TTM) of duodenal stents. The secondary aims were to evaluate 
      clinical outcomes and adverse events (AEs) related to the procedures. Results  
      Data from 23 patients (11 F and 12 M; mean age: 69.5 +/- 11 years old) were 
      collected. In 17 patients (73.9 %) TTM LAMS placement was performed as first 
      intention, while in six patients (26.1 %) it was performed after a failed ERCP. 
      Thirteen patients (56.5 %) underwent the procedure due to advanced pancreatic 
      head neoplasia. One technical failure was experienced (4.3 %). The TTM LAMS 
      placement led to a significant decrease in the serum levels of bilirubin, ALP, 
      GGT, WBC and CRP. No cases of duodenal SEMS occlusion occurred and no other AEs 
      were observed during the follow-up. Conclusions  Concomitant malignant duodenal 
      and biliary obstruction is a challenging condition. Palliation of jaundice using 
      TTM LAMS in patients already treated with duodenal stent is associated to 
      promising technical and clinical outcomes.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commecial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Mangiavillano, Benedetto
AU  - Mangiavillano B
AD  - Gastrointestinal Endoscopy Unit - Humanitas Mater Domini - Castellanza (VA), 
      Italy.
AD  - Humanitas University, Pieve Emanuele (MI), Italy.
FAU - Kunda, Rastislav
AU  - Kunda R
AD  - Department of Surgery, Department of Gastroenterology and Hepatology, and 
      Department of Advanced Interventional Endoscopy, Universitair Ziekenhuis Brussel, 
      Vrije Universiteit Brussel, Brussels, Belgium.
AD  - Department of Surgical Gastroenterology, Aarhus University Hospital, Aarhus, 
      Denmark.
FAU - Robles-Medranda, Carlos
AU  - Robles-Medranda C
AD  - Instituto Ecuatoriano de Enfermedades Digestivas (IECED), Guayaquil, Ecuador.
FAU - Oleas, Roberto
AU  - Oleas R
AD  - Instituto Ecuatoriano de Enfermedades Digestivas (IECED), Guayaquil, Ecuador.
FAU - Anderloni, Andrea
AU  - Anderloni A
AD  - Endoscopy Unit, Istituto Clinico Humanitas Research Hospital, Milan.
FAU - Sportes, Adrien
AU  - Sportes A
AD  - Digestive Endoscopy, Institut Arnault TZANCK Gastroenterology Unit, 
      Saint-Laurent-du-Var, France.
FAU - Fabbri, Carlo
AU  - Fabbri C
AD  - Digestive Endoscopy Unit, Endoscopy Unit, Morgagni-Pietrantoni Hospital, Forli, 
      Italy.
FAU - Binda, Cecilia
AU  - Binda C
AD  - Digestive Endoscopy Unit, Endoscopy Unit, Morgagni-Pietrantoni Hospital, Forli, 
      Italy.
FAU - Auriemma, Francesco
AU  - Auriemma F
AD  - Gastrointestinal Endoscopy Unit - Humanitas Mater Domini - Castellanza (VA), 
      Italy.
FAU - Eusebi, Leonardo H
AU  - Eusebi LH
AD  - Endoscopy Unit, Department of Medical and Surgical Sciences, Sant'Orsola 
      University Hospital, Bologna, Italy.
FAU - Frazzoni, Leonardo
AU  - Frazzoni L
AD  - Endoscopy Unit, Department of Medical and Surgical Sciences, Sant'Orsola 
      University Hospital, Bologna, Italy.
FAU - Fuccio, Lorenzo
AU  - Fuccio L
AD  - Endoscopy Unit, Department of Medical and Surgical Sciences, Sant'Orsola 
      University Hospital, Bologna, Italy.
FAU - Colombo, Matteo
AU  - Colombo M
AD  - Endoscopy Unit, Istituto Clinico Humanitas Research Hospital, Milan.
FAU - Fugazza, Alessandro
AU  - Fugazza A
AD  - Endoscopy Unit, Istituto Clinico Humanitas Research Hospital, Milan.
FAU - Bianchetti, Mario
AU  - Bianchetti M
AD  - Gastrointestinal Endoscopy Unit - Humanitas Mater Domini - Castellanza (VA), 
      Italy.
FAU - Repici, Alessandro
AU  - Repici A
AD  - Humanitas University, Pieve Emanuele (MI), Italy.
AD  - Endoscopy Unit, Istituto Clinico Humanitas Research Hospital, Milan.
LA  - eng
PT  - Journal Article
DEP - 20210218
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC7899809
COIS- Competing interests The authors declare that they have no conflict of interest.
EDAT- 2021/03/04 06:00
MHDA- 2021/03/04 06:01
PMCR- 2021/03/01
CRDT- 2021/03/03 05:48
PHST- 2021/03/03 05:48 [entrez]
PHST- 2021/03/04 06:00 [pubmed]
PHST- 2021/03/04 06:01 [medline]
PHST- 2021/03/01 00:00 [pmc-release]
AID - 10.1055/a-1333-1053 [doi]
PST - ppublish
SO  - Endosc Int Open. 2021 Mar;9(3):E324-E330. doi: 10.1055/a-1333-1053. Epub 2021 Feb 
      18.