PMID- 33655032
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210305
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 9
IP  - 3
DP  - 2021 Mar
TI  - A pilot study of virtual reality as an alternative to pharmacological sedation 
      during colonoscopy.
PG  - E343-E347
LID - 10.1055/a-1339-0724 [doi]
AB  - Background and study aims  Conscious sedation is routinely administered for 
      colonoscopy but is associated with risks and inconveniences. We sought to 
      determine whether virtual reality (VR) may be a feasible alternative. Patients 
      and methods  Twenty-seven individuals scheduled for screening/surveillance 
      colonoscopy participated. The VR device was activated throughout the colonoscopy, 
      but subjects could opt out and request standard medications. Questionnaires were 
      administered, and variables were assessed on a scale of 1 to 10. Results  Cecal 
      intubation was achieved in all cases without adverse events (AEs). Study 
      colonoscopies were completed without pharmacological rescue in 26 of 27 patients 
      (96.3 %) and procedure times were comparable to baseline. Subjects reported 
      minimal pain, high satisfaction, and willingness to use VR for future 
      colonoscopies to avoid narcotics and resume normal activities including driving. 
      Conclusion  Replacing pharmacological sedation with VR did not impact colonoscopy 
      completion rates, procedure time, or AEs. Satisfaction was high and only one 
      subject (3.7 %) chose to suspend VR. VR can be an effective alternative for 
      patients undergoing colonoscopy who prefer to avoid narcotics.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commecial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Friedman, Madeline
AU  - Friedman M
AD  - Gastroenterology Division, Department of Medicine, Massachusetts General 
      Hospital, Harvard Medical School, Boston, Massachusetts, United States.
FAU - Rand, Kyle
AU  - Rand K
AD  - Rendever, Incorporated, Somerville, Massachusetts, United States.
FAU - Patel, Tobias
AU  - Patel T
AD  - Rendever, Incorporated, Somerville, Massachusetts, United States.
FAU - Colizzo, Francis
AU  - Colizzo F
AD  - Gastroenterology Division, Department of Medicine, Massachusetts General 
      Hospital, Harvard Medical School, Boston, Massachusetts, United States.
FAU - Carolan, Peter
AU  - Carolan P
AD  - Gastroenterology Division, Department of Medicine, Massachusetts General 
      Hospital, Harvard Medical School, Boston, Massachusetts, United States.
FAU - Kelsey, Peter
AU  - Kelsey P
AD  - Gastroenterology Division, Department of Medicine, Massachusetts General 
      Hospital, Harvard Medical School, Boston, Massachusetts, United States.
FAU - Chung, Daniel C
AU  - Chung DC
AD  - Gastroenterology Division, Department of Medicine, Massachusetts General 
      Hospital, Harvard Medical School, Boston, Massachusetts, United States.
LA  - eng
PT  - Journal Article
DEP - 20210218
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC7892271
COIS- Competing interests Mr. Rand is an owner of Rendever, Inc. Mr. Patel is an 
      employee of Rendever, Inc.
EDAT- 2021/03/04 06:00
MHDA- 2021/03/04 06:01
PMCR- 2021/03/01
CRDT- 2021/03/03 05:48
PHST- 2020/07/21 00:00 [received]
PHST- 2020/10/05 00:00 [accepted]
PHST- 2021/03/03 05:48 [entrez]
PHST- 2021/03/04 06:00 [pubmed]
PHST- 2021/03/04 06:01 [medline]
PHST- 2021/03/01 00:00 [pmc-release]
AID - 10.1055/a-1339-0724 [doi]
PST - ppublish
SO  - Endosc Int Open. 2021 Mar;9(3):E343-E347. doi: 10.1055/a-1339-0724. Epub 2021 Feb 
      18.