PMID- 33663424
OWN - NLM
STAT- MEDLINE
DCOM- 20211011
LR  - 20211011
IS  - 1471-2466 (Electronic)
IS  - 1471-2466 (Linking)
VI  - 21
IP  - 1
DP  - 2021 Mar 5
TI  - Evaluation of percutaneous transcatheter embolization for pulmonary arteriovenous 
      malformations.
PG  - 77
LID - 10.1186/s12890-021-01448-z [doi]
LID - 77
AB  - BACKGROUND: The purpose of this study was to assess the safety and efficacy of 
      percutaneous transcatheter embolization (TCE) for the treatment of pulmonary 
      arteriovenous malformations (PAVMs). METHODS: Forty-three consecutive patients 
      (n = 17 males; n = 26 females) with 72 untreated PAVMs underwent coil and/or plug 
      embolization between January 2010 and February 2018. The mean patient age was 
      42 +/- 14 years (range 19-71 years). The median size of the feeding artery was 
      7.9 +/- 2.9 mm (range 3.5-14.0 mm). The arterial blood gas level and cardiac 
      function of all patients were analysed. The technical success rate, 
      recanalization rate, and complications were evaluated. Computed tomography 
      angiography (CTA) examinations were scheduled for 12 months after treatment and 
      every 2-4 years thereafter. RESULTS: Twenty-five PAVMs were treated with coils 
      alone, twenty-one were treated with plugs alone, and twenty-six were treated with 
      both coils and plugs. The technical success rate was 100%. There were no 
      complications during operation. However, one patient (2.3%) had pulmonary 
      thrombosis and embolism post-operation. The patients' pre-operative and 
      post-operative PaO(2) and SaO(2) levels were significantly different (p < 0.01). 
      A comparison of the New York Heart Association (NYHA) grade before and after 
      embolization in all patients showed a significant decrease in the post-operative 
      grade (p < 0.01). The 72 PAVMs were divided into three groups (coils only group 
      [n = 25], plugs only group [n = 21], and coils/plugs combined group [n = 26]). 
      After 12 months of follow-up, there were seven reperfusion PAVMs in the coil 
      group, seven reperfusion PAVMs in the plug group, and 1 reperfusion PAVM in the 
      combined group. There were significant differences between the two groups and the 
      combined group. CONCLUSION: Percutaneous TCE is safe and effective for the 
      treatment of PAVMs. A combination of coils and vascular plugs may be useful for 
      preventing recanalization after the embolization of PAVMs.
FAU - Wu, ZhengZhong
AU  - Wu Z
AD  - Department of Interventional Radiology, Fujian Medical University Union Hospital, 
      29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
FAU - Lin, JunQing
AU  - Lin J
AD  - Department of Interventional Radiology, Fujian Medical University Union Hospital, 
      29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
FAU - Yang, WeiZhu
AU  - Yang W
AD  - Department of Interventional Radiology, Fujian Medical University Union Hospital, 
      29 Xinquan Road, Fuzhou, 350001, Fujian Province, China. drweizhuyang@163.com.
FAU - Jiang, Na
AU  - Jiang N
AD  - Department of Interventional Radiology, Fujian Medical University Union Hospital, 
      29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
FAU - Huang, Ning
AU  - Huang N
AD  - Department of Interventional Radiology, Fujian Medical University Union Hospital, 
      29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
FAU - Clavijo, Leonardo C
AU  - Clavijo LC
AD  - Division of Cardiovascular Medicine, Keck School of Medicine, University of 
      Southern California, Los Angeles, CA, USA.
LA  - eng
PT  - Journal Article
DEP - 20210305
PL  - England
TA  - BMC Pulm Med
JT  - BMC pulmonary medicine
JID - 100968563
SB  - IM
MH  - Adult
MH  - Aged
MH  - Arteriovenous Malformations/*complications/diagnostic imaging/*therapy
MH  - *Blood Vessel Prosthesis
MH  - Computed Tomography Angiography
MH  - Embolization, Therapeutic/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Artery/abnormalities/diagnostic imaging
MH  - Pulmonary Veins/abnormalities/diagnostic imaging
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Young Adult
PMC - PMC7934521
OTO - NOTNLM
OT  - Coil
OT  - Embolization
OT  - Plug
OT  - Pulmonary arteriovenous malformation
COIS- The authors declare that they have no competing interests.
EDAT- 2021/03/06 06:00
MHDA- 2021/10/12 06:00
PMCR- 2021/03/05
CRDT- 2021/03/05 05:39
PHST- 2020/12/22 00:00 [received]
PHST- 2021/02/16 00:00 [accepted]
PHST- 2021/03/05 05:39 [entrez]
PHST- 2021/03/06 06:00 [pubmed]
PHST- 2021/10/12 06:00 [medline]
PHST- 2021/03/05 00:00 [pmc-release]
AID - 10.1186/s12890-021-01448-z [pii]
AID - 1448 [pii]
AID - 10.1186/s12890-021-01448-z [doi]
PST - epublish
SO  - BMC Pulm Med. 2021 Mar 5;21(1):77. doi: 10.1186/s12890-021-01448-z.