PMID- 33666739
OWN - NLM
STAT- MEDLINE
DCOM- 20220330
LR  - 20220401
IS  - 1432-0460 (Electronic)
IS  - 0179-051X (Print)
IS  - 0179-051X (Linking)
VI  - 37
IP  - 1
DP  - 2022 Feb
TI  - Swallowing Outcomes Following Voice Therapy in Multiple System Atrophy with 
      Dysphagia: Comparison of Treatment Efficacy with Parkinson's Disease.
PG  - 198-206
LID - 10.1007/s00455-021-10265-9 [doi]
AB  - Difficulties with speech and swallowing occur in patients with Parkinsonism. Lee 
      Silverman Voice Treatment (LSVT) is proven as an effective treatment for speech 
      and swallowing function in idiopathic Parkinson's disease (IPD). The effect of 
      LSVT on swallowing function in multiple system atrophy-cerebellar type (MSA-C) is 
      unknown. We sought to determine LSVT's effect on swallowing function in MSA-C 
      patients compared to IPD patients. LSVT-LOUD was performed on 13 patients with 
      Parkinsonism (6 IPD and 7 MSA-C). Maximum phonation time (MPT), voice intensity, 
      Speech Handicap Index-15 (SHI-15), Swallowing-Quality of Life (SWAL-QOL), 
      National Institutes of Health-swallowing safety scale (NIH-SSS), and 
      videofluoroscopic dysphagia scale (VDS) before and after LSVT were analyzed and 
      reevaluated three months after treatment. The IPD and MSA-C groups showed 
      significant improvements in overall speech and swallowing measures after LSVT. In 
      particular, pharyngeal phase score and total score of VDS improved significantly 
      in both groups. A two-way repeated-measure ANOVA revealed a significant main 
      effect for time in the MPT, voice intensity, NIH-SSS, pharyngeal phase score and 
      total score of VDS, psychosocial subdomain of SHI-15, and SWAL-QOL. The MSA-C 
      group experienced less overall improvement in swallowing function, but the two 
      groups had an analogous pattern of improvement. In conclusion, LSVT is effective 
      for enhancing swallowing function, particularly in the pharyngeal phase, in both 
      IPD and MSA-C patients. This study demonstrated that LSVT elicits significant 
      improvements in MSA-C patients. We deemed LSVT to be an effective treatment for 
      IPD and MSA-C patients who suffer from dysphagia.
CI  - (c) 2021. The Author(s).
FAU - Park, Alyssa
AU  - Park A
AD  - Graduate Program in Speech and Language Pathology, Yonsei University College of 
      Medicine, Seoul, 03722, Korea.
FAU - Jang, Su-Jeong
AU  - Jang SJ
AD  - Graduate Program in Speech and Language Pathology, Yonsei University College of 
      Medicine, Seoul, 03722, Korea.
FAU - Kim, No-Eul
AU  - Kim NE
AD  - Graduate Program in Speech and Language Pathology, Yonsei University College of 
      Medicine, Seoul, 03722, Korea.
FAU - Kim, Tae-Hui
AU  - Kim TH
AD  - Graduate Program in Speech and Language Pathology, Yonsei University College of 
      Medicine, Seoul, 03722, Korea.
FAU - Sohn, Young Ho
AU  - Sohn YH
AD  - Department of Neurology, Yonsei University College of Medicine, Seoul, 03711, 
      Korea.
FAU - Kim, HyangHee
AU  - Kim H
AUID- ORCID: 0000-0003-4949-2512
AD  - Graduate Program in Speech and Language Pathology, Yonsei University College of 
      Medicine, Seoul, 03722, Korea.
AD  - Department and Research Institute of Rehabilitation Medicine, Yonsei University 
      College of Medicine, Seoul, 03722, Korea.
FAU - Cho, Sung-Rae
AU  - Cho SR
AUID- ORCID: 0000-0003-1429-2684
AD  - Department and Research Institute of Rehabilitation Medicine, Yonsei University 
      College of Medicine, Seoul, 03722, Korea. srcho918@yuhs.ac.
AD  - Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of 
      Medicine, Seoul, 03722, Korea. srcho918@yuhs.ac.
AD  - Graduate Program of NanoScience and Technology, Yonsei University College of 
      Medicine, Seoul, 03722, Korea. srcho918@yuhs.ac.
AD  - Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of 
      Medicine, Seoul, 03722, Korea. srcho918@yuhs.ac.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20210305
PL  - United States
TA  - Dysphagia
JT  - Dysphagia
JID - 8610856
SB  - IM
MH  - Deglutition
MH  - *Deglutition Disorders/etiology/therapy
MH  - Humans
MH  - *Multiple System Atrophy/complications/therapy
MH  - *Parkinson Disease
MH  - Quality of Life
MH  - Treatment Outcome
MH  - Voice Training
PMC - PMC8844176
OTO - NOTNLM
OT  - Deglutition
OT  - Deglutition disorders
OT  - Lee silverman voice treatment
OT  - Multiple system atrophy
OT  - Parkinsonism
EDAT- 2021/03/06 06:00
MHDA- 2022/03/31 06:00
PMCR- 2021/03/05
CRDT- 2021/03/05 12:12
PHST- 2020/02/19 00:00 [received]
PHST- 2021/02/04 00:00 [accepted]
PHST- 2021/03/06 06:00 [pubmed]
PHST- 2022/03/31 06:00 [medline]
PHST- 2021/03/05 12:12 [entrez]
PHST- 2021/03/05 00:00 [pmc-release]
AID - 10.1007/s00455-021-10265-9 [pii]
AID - 10265 [pii]
AID - 10.1007/s00455-021-10265-9 [doi]
PST - ppublish
SO  - Dysphagia. 2022 Feb;37(1):198-206. doi: 10.1007/s00455-021-10265-9. Epub 2021 Mar 
      5.