PMID- 33670461
OWN - NLM
STAT- MEDLINE
DCOM- 20210419
LR  - 20231110
IS  - 1422-0067 (Electronic)
IS  - 1422-0067 (Linking)
VI  - 22
IP  - 4
DP  - 2021 Feb 18
TI  - Outcomes of Lower Extremity Endovascular Revascularization: Potential Predictors 
      and Prevention Strategies.
LID - 10.3390/ijms22042002 [doi]
LID - 2002
AB  - Peripheral artery disease (PAD) is a manifestation of atherosclerosis, which may 
      affect arteries of the lower extremities. The most dangerous PAD complication is 
      chronic limb-threatening ischemia (CLTI). Without revascularization, CLTI often 
      causes limb loss. However, neither open surgical revascularization nor 
      endovascular treatment (EVT) ensure long-term success and freedom from restenosis 
      and revascularization failure. In recent years, EVT has gained growing acceptance 
      among all vascular specialties, becoming the primary approach of 
      revascularization in patients with CLTI. In clinical practice, different clinical 
      outcomes after EVT in patients with similar comorbidities undergoing the same 
      procedure (in terms of revascularization technique and localization of the 
      disease) cause unsolved issues that need to be addressed. Nowadays, risk 
      management of revascularization failure is one of the major challenges in the 
      vascular field. The aim of this literature review is to identify potential 
      predictors for lower extremity endovascular revascularization outcomes and 
      possible prevention strategies.
FAU - Biscetti, Federico
AU  - Biscetti F
AUID- ORCID: 0000-0001-7449-657X
AD  - Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
AD  - Cardiovascular Internal Medicine Unit, Fondazione Policlinico Universitario A. 
      Gemelli IRCCS, 00168 Roma, Italy.
FAU - Nardella, Elisabetta
AU  - Nardella E
AUID- ORCID: 0000-0001-7119-0364
AD  - Department of Medical and Surgical Sciences, Universita Cattolica del Sacro 
      Cuore, 00168 Roma, Italy.
FAU - Rando, Maria Margherita
AU  - Rando MM
AUID- ORCID: 0000-0003-3167-4748
AD  - Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
AD  - Cardiovascular Internal Medicine Unit, Fondazione Policlinico Universitario A. 
      Gemelli IRCCS, 00168 Roma, Italy.
FAU - Cecchini, Andrea Leonardo
AU  - Cecchini AL
AD  - Department of Medical and Surgical Sciences, Universita Cattolica del Sacro 
      Cuore, 00168 Roma, Italy.
FAU - Gasbarrini, Antonio
AU  - Gasbarrini A
AD  - Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
AD  - Department of Medical and Surgical Sciences, Universita Cattolica del Sacro 
      Cuore, 00168 Roma, Italy.
FAU - Massetti, Massimo
AU  - Massetti M
AD  - Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
AD  - Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. 
      Gemelli IRCCS, 00168 Roma, Italy.
FAU - Flex, Andrea
AU  - Flex A
AD  - Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
AD  - Cardiovascular Internal Medicine Unit, Fondazione Policlinico Universitario A. 
      Gemelli IRCCS, 00168 Roma, Italy.
AD  - Department of Medical and Surgical Sciences, Universita Cattolica del Sacro 
      Cuore, 00168 Roma, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210218
PL  - Switzerland
TA  - Int J Mol Sci
JT  - International journal of molecular sciences
JID - 101092791
SB  - IM
MH  - Endovascular Procedures/adverse effects/*methods
MH  - Humans
MH  - Ischemia/diagnosis/etiology/*prevention & control
MH  - Lower Extremity/*blood supply
MH  - Outcome Assessment, Health Care/methods/statistics & numerical data
MH  - Peripheral Arterial Disease/*surgery
MH  - Postoperative Complications/diagnosis/etiology/*prevention & control
MH  - Risk Assessment/methods/statistics & numerical data
MH  - Risk Factors
PMC - PMC7922574
OTO - NOTNLM
OT  - chronic limb-threatening ischemia (CLTI)
OT  - peripheral artery disease (PAD)
OT  - revascularization
COIS- The authors declare no conflict of interest.
EDAT- 2021/03/07 06:00
MHDA- 2021/04/20 06:00
PMCR- 2021/02/18
CRDT- 2021/03/06 01:07
PHST- 2020/12/29 00:00 [received]
PHST- 2021/02/11 00:00 [revised]
PHST- 2021/02/12 00:00 [accepted]
PHST- 2021/03/06 01:07 [entrez]
PHST- 2021/03/07 06:00 [pubmed]
PHST- 2021/04/20 06:00 [medline]
PHST- 2021/02/18 00:00 [pmc-release]
AID - ijms22042002 [pii]
AID - ijms-22-02002 [pii]
AID - 10.3390/ijms22042002 [doi]
PST - epublish
SO  - Int J Mol Sci. 2021 Feb 18;22(4):2002. doi: 10.3390/ijms22042002.