PMID- 3367614
OWN - NLM
STAT- MEDLINE
DCOM- 19880613
LR  - 20061115
IS  - 0300-8630 (Print)
IS  - 0300-8630 (Linking)
VI  - 200
IP  - 1
DP  - 1988 Jan-Feb
TI  - [Congenital hyperthyroidism caused by diaplacental exchange of thyrotropin 
      receptor antibodies].
PG  - 74-7
AB  - We describe the case of a premature baby, extremely small for date whose mother 
      had an untreated hyperthyroidism during pregnancy. Severe symptoms of connatal 
      hyperthyroidism appeared after a latency period of seven days. As the underlying 
      cause we suggest the placental transmission of thyrotropin-receptor-antibodies 
      (TRAb), which were elevated in the mother and the newborn. Main symptoms in the 
      newborn were tachycardia, tachypnea, sweating and diarrhea.
FAU - Eyb, H
AU  - Eyb H
AD  - Universitats-Kinderklinik Graz.
FAU - Sperger, H
AU  - Sperger H
FAU - Borkenstein, M
AU  - Borkenstein M
FAU - Muller, W
AU  - Muller W
FAU - Passath, A
AU  - Passath A
LA  - ger
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - Connatale Hyperthyreose durch diaplazentar ubertragene 
      Thyreotropin-Rezeptoren-Antikorper (TRAK).
PL  - Germany
TA  - Klin Padiatr
JT  - Klinische Padiatrie
JID - 0326144
RN  - 0 (Autoantibodies)
RN  - 0 (Receptors, Thyrotropin)
SB  - IM
MH  - Autoantibodies/*analysis
MH  - Female
MH  - Graves Disease/immunology
MH  - Humans
MH  - Hyperthyroidism/*congenital/immunology
MH  - Infant, Newborn
MH  - *Maternal-Fetal Exchange
MH  - Pregnancy
MH  - Receptors, Thyrotropin/*immunology
MH  - Thyroid Function Tests
EDAT- 1988/01/01 00:00
MHDA- 1988/01/01 00:01
CRDT- 1988/01/01 00:00
PHST- 1988/01/01 00:00 [pubmed]
PHST- 1988/01/01 00:01 [medline]
PHST- 1988/01/01 00:00 [entrez]
AID - 10.1055/s-2008-1033690 [doi]
PST - ppublish
SO  - Klin Padiatr. 1988 Jan-Feb;200(1):74-7. doi: 10.1055/s-2008-1033690.