PMID- 33676481 OWN - NLM STAT- MEDLINE DCOM- 20210310 LR - 20210312 IS - 1471-2482 (Electronic) IS - 1471-2482 (Linking) VI - 21 IP - 1 DP - 2021 Mar 6 TI - Needle Adjustment Free (NAF) running suture technique (PAN suture) in laparoscopic partial nephrectomy. PG - 118 LID - 10.1186/s12893-021-01112-7 [doi] LID - 118 AB - BACKGROUND: It is proposed a new running suture technique called Needle Adjustment Free (NAF) technique, or PAN suture. The efficiency and the safety were evaluated in laparoscopic partial nephrectomy. METHODS: This new running suture technique avoids the Needle Adjustment method used in traditional techniques. The new continuous suture technique (11 patients) was compared with the traditional continuous suture method (33 patients) used in both transperitoneal and retroperitoneal laparoscopic partial nephrectomy (LPN) in terms of suture time (ST), warm ischemia time (WIT), blood loss (BL), open conversion rate and post-op discharge time, post-op bleeding, post-op DVT, DeltaGFR (affected side, 3 months post-op). Differences were considered significant when P < 0.05. RESULTS: ST in the PAN suture group was 30.37 +/- 16.39 min, which was significant shorter (P = 0.0011) than in the traditional technique group which was 13.68 +/- 3.33 min. WIT in the traditional technique group was 28.73 +/- 7.89 min, while in the PAN suture group was 20.64 +/- 5.04 min, P = 0.0028. The BL in entirety in the traditional technique group was 141.56 +/- 155.23 mL, and in the PAN suture group was 43.18 +/- 31.17 mL (P = 0.0017). BL in patients without massive bleeding in the traditional technique group was significantly greater than in the PAN suture group at 101.03 +/- 68.73 mL versus 43.18 +/- 31.17 mL (P = 0.0008). The open conversion rate was 0 % in both groups. There was no significant difference between the two groups in postoperative discharge time, post-op bleeding, post-op DVT, DeltaGFR (affected side, 3 months post-op). CONCLUSIONS: The NAF running suture technique, or PAN suture, leading to less ST, WIT and BL, which was shown to be more effective and safer than the traditional technique used for LPN. A further expanded research with larger sample size is needed. FAU - Pan, Jun-Wei AU - Pan JW AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Zhang, Xiang AU - Zhang X AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Jin, Xing-Wei AU - Jin XW AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Liu, Xiao AU - Liu X AD - Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. FAU - Tu, Wei-Chao AU - Tu WC AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Wang, Xian-Jin AU - Wang XJ AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Huang, Bao-Xing AU - Huang BX AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Xu, Da AU - Xu D AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Lu, Guo-Liang AU - Lu GL AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Wang, Da-Wei AU - Wang DW AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. FAU - Wang, Xiang-Hui AU - Wang XH AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. wxh@medmail.com.cn. FAU - Shao, Yuan AU - Shao Y AD - Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, No. 999, Xi Wang Road, Shanghai, 201801, China. shaoyuan15@126.com. LA - eng GR - JDKW-2018-W09/Agricultural and Social Research Projects of District Jiading, Shanghai/ GR - 2019RCPY-B12/Youth Talents Plan of Shanghai Ruijin Hospital North/ PT - Journal Article DEP - 20210306 PL - England TA - BMC Surg JT - BMC surgery JID - 100968567 SB - IM MH - Humans MH - *Laparoscopy MH - *Nephrectomy/methods MH - *Suture Techniques MH - Treatment Outcome PMC - PMC7937216 OTO - NOTNLM OT - Laparoscopic partial nephrectomy OT - Needle Adjustment Free OT - Needle out-needle in OT - PAN suture OT - Suture efficiency COIS- The authors declare that they have no competing interests. EDAT- 2021/03/08 06:00 MHDA- 2021/03/11 06:00 PMCR- 2021/03/06 CRDT- 2021/03/07 20:23 PHST- 2020/08/31 00:00 [received] PHST- 2021/02/21 00:00 [accepted] PHST- 2021/02/09 00:00 [revised] PHST- 2021/03/07 20:23 [entrez] PHST- 2021/03/08 06:00 [pubmed] PHST- 2021/03/11 06:00 [medline] PHST- 2021/03/06 00:00 [pmc-release] AID - 10.1186/s12893-021-01112-7 [pii] AID - 1112 [pii] AID - 10.1186/s12893-021-01112-7 [doi] PST - epublish SO - BMC Surg. 2021 Mar 6;21(1):118. doi: 10.1186/s12893-021-01112-7.