PMID- 33680001 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20210310 IS - 2174-0852 (Electronic) IS - 1697-2600 (Print) IS - 1697-2600 (Linking) VI - 21 IP - 2 DP - 2021 May-Aug TI - Reducing stress and promoting well-being in healthcare workers using mindfulness-based cognitive therapy for life. PG - 100227 LID - 10.1016/j.ijchp.2021.100227 [doi] LID - 100227 AB - Healthcare workers play a critical role in the health of a nation, yet rates of healthcare worker stress are disproportionately high. We evaluated whether mindfulness-based cognitive therapy for life (MBCT-L), could reduce stress in healthcare workers and target a range of secondary outcomes. Method: This is the first parallel randomised controlled trial of MBCT-L. Participants were NHS workers, who were randomly assigned (1:1) to receive either MBCT-L or wait-list. The primary outcome was self-reported stress at post-intervention. Secondary variables were well-being, depression, anxiety, and work-related outcomes. Mixed regressions were used. Mindfulness and self/other-compassion were explored as potential mechanisms of effects on stress and wellbeing. Results: We assigned 234 participants to MBCT-L (n = 115) or to wait-list (n = 119). 168 (72%) participants completed the primary outcome and of those who started the MBCT-L 73.40% (n = 69) attended the majority of the sessions. MBCT-L ameliorated stress compared with controls (B = 2.60, 95% CI = 1.63‒3.56; d = -0.72; p < .0001). Effects were also found for well-being, depression and anxiety, but not for work-related outcomes. Mindfulness and self-compassion mediated effects on stress and wellbeing. Conclusions: MBCT-L could be an effective and acceptable part of a wider healthcare workers well-being and mental health strategy. CI - (c) 2021 Asociacion Espanola de Psicologia Conductual. Published by Elsevier Espana, S.L.U. FAU - Strauss, Clara AU - Strauss C AD - School of Psychology, University of Sussex, United Kingdom. AD - Research Department, Sussex Partnership NHS Foundation Trust, Sussex Education Centre, Mill View Hospital, United Kingdom. FAU - Gu, Jenny AU - Gu J AD - Research Department, Sussex Partnership NHS Foundation Trust, Sussex Education Centre, Mill View Hospital, United Kingdom. FAU - Montero-Marin, Jesus AU - Montero-Marin J AD - Department of Psychiatry, University of Oxford, Warneford Hospital, United Kingdom. FAU - Whittington, Adrian AU - Whittington A AD - Health Education England, Kent, Surrey and Sussex, United Kingdom. FAU - Chapman, Cavita AU - Chapman C AD - Health Education England, Kent, Surrey and Sussex, United Kingdom. FAU - Kuyken, Willem AU - Kuyken W AD - Department of Psychiatry, University of Oxford, Warneford Hospital, United Kingdom. LA - eng PT - Journal Article DEP - 20210218 PL - Spain TA - Int J Clin Health Psychol JT - International journal of clinical and health psychology : IJCHP JID - 101237969 PMC - PMC7903308 OTO - NOTNLM OT - Experiment OT - Healthcare workers OT - MBCT-L OT - Mindfulness OT - Stress EDAT- 2021/03/09 06:00 MHDA- 2021/03/09 06:01 PMCR- 2021/02/18 CRDT- 2021/03/08 05:51 PHST- 2020/10/25 00:00 [received] PHST- 2021/01/04 00:00 [accepted] PHST- 2021/03/08 05:51 [entrez] PHST- 2021/03/09 06:00 [pubmed] PHST- 2021/03/09 06:01 [medline] PHST- 2021/02/18 00:00 [pmc-release] AID - S1697-2600(21)00008-9 [pii] AID - 100227 [pii] AID - 10.1016/j.ijchp.2021.100227 [doi] PST - ppublish SO - Int J Clin Health Psychol. 2021 May-Aug;21(2):100227. doi: 10.1016/j.ijchp.2021.100227. Epub 2021 Feb 18.