PMID- 33680526
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210310
IS  - 2090-6781 (Print)
IS  - 2090-679X (Electronic)
IS  - 2090-679X (Linking)
VI  - 2021
DP  - 2021
TI  - A Case of Low-Grade Oncocytic Tumor/Chromophobe Renal Cell Carcinoma (Oncocytic 
      Variant) of the Kidney.
PG  - 6684777
LID - 10.1155/2021/6684777 [doi]
LID - 6684777
AB  - The oncocytic variant of chromophobe renal cell carcinoma (oChRCC) and low-grade 
      oncocytic tumor (LOT) is introduced as new renal disease entity. Both of these 
      tumors are low-grade malignancies consisting of cells with eosinophilic 
      cytoplasm. Distinguishing between eosinophilic variant of chromophobe renal cell 
      carcinoma (eCRCC) and oncocytoma is often a diagnostic challenge in routine 
      surgical pathology. However, oChRCC and LOT might be independent disease entities 
      that might not fit completely into any of these categories. Histologically, these 
      tumors have greater morphological similarity with oncocytoma than with ChRCC. 
      However, immunohistochemically, they exhibit diffuse and dense positivity for CK7 
      and are negative for CD117. In the present case, we initially had difficulty 
      distinguishing among oncocytoma, eCRCC, and type 2 papillary renal cell carcinoma 
      (2-pRCC). However, after learning about new disease entities such as oChRCC and 
      LOT, we were able to diagnose this tumor.
CI  - Copyright (c) 2021 Noriyoshi Ishikawa et al.
FAU - Ishikawa, Noriyoshi
AU  - Ishikawa N
AUID- ORCID: 0000-0001-5741-0981
AD  - Department of Pathology, Shonan Fujisawa Tokushukai Hospital, 1-5-1 
      Tsujido-kandai, Fujisawa, Kanagawa 251-0041, Japan.
FAU - Kimura, Nao
AU  - Kimura N
AD  - Department of Pathology, Shonan Fujisawa Tokushukai Hospital, 1-5-1 
      Tsujido-kandai, Fujisawa, Kanagawa 251-0041, Japan.
FAU - Yoshida, Toshio
AU  - Yoshida T
AD  - Department of Urology, Shonan Fujisawa Tokushukai Hospital, Japan.
FAU - Yoshimura, Ichiro
AU  - Yoshimura I
AD  - Department of Urology, Shonan Fujisawa Tokushukai Hospital, Japan.
FAU - Nakahara, Ken
AU  - Nakahara K
AD  - Department of Urology, Shonan Fujisawa Tokushukai Hospital, Japan.
FAU - Tsuzuki, Toyonori
AU  - Tsuzuki T
AD  - Department of Surgical Pathology, Aichi Medical University, School of Medicine, 
      Japan.
FAU - Tokunaga, Osamu
AU  - Tokunaga O
AD  - Department of Pathology, Shonan Fujisawa Tokushukai Hospital, 1-5-1 
      Tsujido-kandai, Fujisawa, Kanagawa 251-0041, Japan.
LA  - eng
PT  - Case Reports
DEP - 20210218
PL  - United States
TA  - Case Rep Pathol
JT  - Case reports in pathology
JID - 101576609
PMC - PMC7906815
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2021/03/09 06:00
MHDA- 2021/03/09 06:01
PMCR- 2021/02/18
CRDT- 2021/03/08 05:53
PHST- 2020/11/30 00:00 [received]
PHST- 2021/01/18 00:00 [accepted]
PHST- 2021/03/08 05:53 [entrez]
PHST- 2021/03/09 06:00 [pubmed]
PHST- 2021/03/09 06:01 [medline]
PHST- 2021/02/18 00:00 [pmc-release]
AID - 10.1155/2021/6684777 [doi]
PST - epublish
SO  - Case Rep Pathol. 2021 Feb 18;2021:6684777. doi: 10.1155/2021/6684777. eCollection 
      2021.