PMID- 33681216
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210310
IS  - 2296-634X (Print)
IS  - 2296-634X (Electronic)
IS  - 2296-634X (Linking)
VI  - 9
DP  - 2021
TI  - Regulation of the Migration of Distinct Dendritic Cell Subsets.
PG  - 635221
LID - 10.3389/fcell.2021.635221 [doi]
LID - 635221
AB  - Dendritic cells (DCs), a class of antigen-presenting cells, are widely present in 
      tissues and apparatuses of the body, and their ability to migrate is key for the 
      initiation of immune activation and tolerogenic immune responses. The importance 
      of DCs migration for their differentiation, phenotypic states, and immunologic 
      functions has attracted widespread attention. In this review, we discussed and 
      compared the chemokines, membrane molecules, and migration patterns of 
      conventional DCs, plasmocytoid DCs, and recently proposed DC subgroups. We also 
      review the promoters and inhibitors that affect DCs migration, including the 
      hypoxia microenvironment, tumor microenvironment, inflammatory factors, and 
      pathogenic microorganisms. Further understanding of the migration mechanisms and 
      regulatory factors of DC subgroups provides new insights for the treatment of 
      diseases, such as infection, tumors, and vaccine preparation.
CI  - Copyright (c) 2021 Feng, Zhou, Yu, Su, Li and Lin.
FAU - Feng, Meng
AU  - Feng M
AD  - Institute of Basic Medicine, Shandong First Medical University & Shandong Academy 
      of Medical Science, Shandong Provincial Hospital Affiliated to Shandong First 
      Medical University, Jinan, China.
FAU - Zhou, Shuping
AU  - Zhou S
AD  - Institute of Basic Medicine, Shandong First Medical University & Shandong Academy 
      of Medical Science, Shandong Provincial Hospital Affiliated to Shandong First 
      Medical University, Jinan, China.
FAU - Yu, Yong
AU  - Yu Y
AD  - Institute of Basic Medicine, Shandong First Medical University & Shandong Academy 
      of Medical Science, Shandong Provincial Hospital Affiliated to Shandong First 
      Medical University, Jinan, China.
FAU - Su, Qinghong
AU  - Su Q
AD  - Institute of Basic Medicine, Shandong First Medical University & Shandong Academy 
      of Medical Science, Shandong Provincial Hospital Affiliated to Shandong First 
      Medical University, Jinan, China.
FAU - Li, Xiaofan
AU  - Li X
AD  - Institute of Basic Medicine, Shandong First Medical University & Shandong Academy 
      of Medical Science, Shandong Provincial Hospital Affiliated to Shandong First 
      Medical University, Jinan, China.
FAU - Lin, Wei
AU  - Lin W
AD  - Institute of Basic Medicine, Shandong First Medical University & Shandong Academy 
      of Medical Science, Shandong Provincial Hospital Affiliated to Shandong First 
      Medical University, Jinan, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210219
PL  - Switzerland
TA  - Front Cell Dev Biol
JT  - Frontiers in cell and developmental biology
JID - 101630250
PMC - PMC7933215
OTO - NOTNLM
OT  - adhesion molecules
OT  - chemokines
OT  - conventional dendritic cells
OT  - dendritic cells
OT  - migration
OT  - plasmacytoid dendritic cells
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2021/03/09 06:00
MHDA- 2021/03/09 06:01
PMCR- 2021/02/19
CRDT- 2021/03/08 05:55
PHST- 2020/11/30 00:00 [received]
PHST- 2021/02/01 00:00 [accepted]
PHST- 2021/03/08 05:55 [entrez]
PHST- 2021/03/09 06:00 [pubmed]
PHST- 2021/03/09 06:01 [medline]
PHST- 2021/02/19 00:00 [pmc-release]
AID - 10.3389/fcell.2021.635221 [doi]
PST - epublish
SO  - Front Cell Dev Biol. 2021 Feb 19;9:635221. doi: 10.3389/fcell.2021.635221. 
      eCollection 2021.