PMID- 33683634
OWN - NLM
STAT- MEDLINE
DCOM- 20230224
LR  - 20230224
IS  - 2240-2993 (Electronic)
IS  - 0300-9009 (Linking)
VI  - 123
IP  - 1
DP  - 2023 Feb
TI  - A resting-state functional MRI study in patients with vestibular migraine during 
      interictal period.
PG  - 99-105
LID - 10.1007/s13760-021-01639-9 [doi]
AB  - To evaluate the spontaneous neuronal activities and the changes of brain 
      functional network in patients with vestibular migraine (VM). Three groups 
      including18 patients with VM, 21 patients with migraine without aura (MWoA) and 
      21 healthy controls (HCs) underwent the scanning of the resting-state fMRI. 
      Covariance analysis and bonferroni multiple comparisons were used to obtain brain 
      regions with significant differences in amplitude of low-frequency fluctuation 
      (ALFF) values. Furthermore, the brain regions with the most significant 
      differences of ALFF values were recognized as a region of interest (ROI) and 
      functional connectivity (FC) analysis was performed in these regions. (1) ALFF: 
      Compared with HCs, patients with VM showed significantly lower ALFF in the right 
      putamen (P < 0.05), and significantly higher ALFF in the right lingual gyrus 
      (P < 0.05). In addition, compared with MWoA patients, patients with VM showed 
      significantly higher ALFF in the right lingual gyrus (P < 0.05). (2) Compared 
      with HCs, VM patients showed significantly higher FC among the cerebellum, the 
      left dorsolateral superior frontal gyrus and the right putamen (P < 0.05) but 
      significantly lower FC among the left median cingulate, paracingulate gyri and 
      the right putamen (P < 0.05). Compared with MWoA patients, VM patients showed 
      significantly higher FC between the cerebellum and the right putamen (P < 0.05) 
      but significantly lower FC among the left median cingulate, paracingulate gyri 
      and the right putamen (P < 0.05). There are functional abnormalities in 
      nociceptive, vestibular and visual cortex regions in patients with VM during the 
      interictal period.
CI  - (c) 2021. Belgian Neurological Society.
FAU - Wang, Shuqing
AU  - Wang S
AD  - Department of Neurology, The Affiliated Hospital of Qingdao University, Jiangsu 
      Road 16, Qingdao, 266003, China.
FAU - Wang, Haiping
AU  - Wang H
AUID- ORCID: 0000-0001-9815-5614
AD  - Department of Neurology, The Affiliated Hospital of Qingdao University, Jiangsu 
      Road 16, Qingdao, 266003, China. 1157318363@qq.com.
FAU - Liu, Xuejun
AU  - Liu X
AD  - Department of Radiology, The Affiliated Hospital of Qingdao University, Jiangsu 
      Road 16, Qingdao, 266003, China.
FAU - Yan, Wenjing
AU  - Yan W
AD  - Department of Neurology, The Affiliated Hospital of Qingdao University, Jiangsu 
      Road 16, Qingdao, 266003, China.
FAU - Wang, Minghui
AU  - Wang M
AD  - Department of Radiology, The Affiliated Hospital of Qingdao University, Jiangsu 
      Road 16, Qingdao, 266003, China.
FAU - Zhao, Renliang
AU  - Zhao R
AD  - Department of Neurology, The Affiliated Hospital of Qingdao University, Jiangsu 
      Road 16, Qingdao, 266003, China.
LA  - eng
GR  - 17-3-3-18-nsh/Qingdao People's Livelihood Science and Technology Project/
PT  - Journal Article
DEP - 20210308
PL  - Italy
TA  - Acta Neurol Belg
JT  - Acta neurologica Belgica
JID - 0247035
SB  - IM
MH  - Humans
MH  - *Brain/diagnostic imaging
MH  - Brain Mapping
MH  - Prefrontal Cortex
MH  - *Migraine without Aura
MH  - Magnetic Resonance Imaging
OTO - NOTNLM
OT  - Cerebellum
OT  - Resting-state functional magnetic resonance imaging
OT  - Vestibular migraine
OT  - Vestibular processing
EDAT- 2021/03/09 06:00
MHDA- 2023/02/25 06:00
CRDT- 2021/03/08 12:17
PHST- 2021/01/03 00:00 [received]
PHST- 2021/02/26 00:00 [accepted]
PHST- 2021/03/09 06:00 [pubmed]
PHST- 2023/02/25 06:00 [medline]
PHST- 2021/03/08 12:17 [entrez]
AID - 10.1007/s13760-021-01639-9 [pii]
AID - 10.1007/s13760-021-01639-9 [doi]
PST - ppublish
SO  - Acta Neurol Belg. 2023 Feb;123(1):99-105. doi: 10.1007/s13760-021-01639-9. Epub 
      2021 Mar 8.