PMID- 33687168
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220421
IS  - 2008-076X (Print)
IS  - 2008-0778 (Electronic)
IS  - 2008-0778 (Linking)
VI  - 15
IP  - 2
DP  - 2021 Apr
TI  - Effect of Low-Intensity Endurance Training and High-Intensity Interval Training 
      on Sperm Quality in Male Rats with Fatty Liver.
PG  - 141-147
LID - 10.22074/IJFS.2020.134593 [doi]
AB  - BACKGROUND: We aimed to investigate the effect of low-intensity endurance 
      training (LIET) and high-intensity interval training (HIIT) on sperm parameters, 
      chromatin status, and oxidative stress in a rat model of non-alcoholic fatty 
      liver disease (NAFLD). MATERIALS AND METHODS: For this experimental study, we 
      divided 40 male Wistar rats into four groups (control, sham, HIIT and LIET) 
      according to diet treatment and exercise training protocol. Liver triglycerides, 
      sperm parameters, sperm lipid peroxidation (BODIPY C11 probe) and chromatin 
      status [chromomycin A3 (CMA3)], and acridine orange [AO] staining) were assessed 
      in these groups at the end of the study. RESULTS: The mean liver triglyceride 
      values significantly improved in both the LIET and HIIT groups compared to the 
      control and sham groups. The mean of testicular volume, sperm concentration, 
      motility, intensity of sperm lipid peroxidation and DNA damage were similar 
      within groups. While, the mean percentage of sperm lipid peroxidation and 
      protamine deficiency were significantly higher in the LIET and HIIT groups 
      compared to the control group. CONCLUSION: Both LIET and HIIT in the rat NAFLD 
      model had no adverse effects on testicular morphometric parameters, sperm 
      concentration, motility, and DNA integrity. However, the mean sperm lipid 
      peroxidation and protamine deficiency were significantly higher in both exercise 
      groups. Our study suggests that exercise or antioxidant supplementation could 
      minimise the adverse effects of oxidant by-products of exercise.
CI  - Copyright(c) by Royan Institute. All rights reserved.
FAU - Hosseini, Mahnaz
AU  - Hosseini M
AD  - Department of Animal Biotechnology, Reproductive Biomedicine Research Center, 
      Royan Institute for Biotechnology, ACECR, Isfahan, Iran.
AD  - Department of Biology, Faculty of Science, Nour Danesh Institute of Higher 
      Education, Isfahan, Iran.
FAU - Alsadat Hashemi, Seyyed Vajiheh
AU  - Alsadat Hashemi SV
AD  - Department of Animal Biotechnology, Reproductive Biomedicine Research Center, 
      Royan Institute for Biotechnology, ACECR, Isfahan, Iran.
AD  - Biology Department, Medical Biotechnology Research Center, Ashkezar Branch, 
      Islamic Azad University, Ashkezar, Yazd, Iran.
FAU - Bagheri, Mohammad Hossein
AU  - Bagheri MH
AD  - Department of Exercise Physiology, Faculty of Sport Sciences, Shahrekord 
      University, Shahrekord, Iran.
FAU - Tavalaee, Marziyeh
AU  - Tavalaee M
AD  - Department of Animal Biotechnology, Reproductive Biomedicine Research Center, 
      Royan Institute for Biotechnology, ACECR, Isfahan, Iran.
FAU - Seifati, Seyed Morteza
AU  - Seifati SM
AD  - Biology Department, Medical Biotechnology Research Center, Ashkezar Branch, 
      Islamic Azad University, Ashkezar, Yazd, Iran.
FAU - Zohrabi, Dina
AU  - Zohrabi D
AD  - Department of Biology, Faculty of Science, Nour Danesh Institute of Higher 
      Education, Isfahan, Iran.
FAU - Nasr-Esfahani, Mohammad Hossein
AU  - Nasr-Esfahani MH
AD  - Department of Animal Biotechnology, Reproductive Biomedicine Research Center, 
      Royan Institute for Biotechnology, ACECR, Isfahan, Iran. Email: 
      mh.nasr-esfahani@royaninstitute.org.
LA  - eng
PT  - Journal Article
DEP - 20210311
PL  - Iran
TA  - Int J Fertil Steril
JT  - International journal of fertility & sterility
JID - 101487941
PMC - PMC8052797
OTO - NOTNLM
OT  - DNA Damage
OT  - Fatty Liver
OT  - High-Intensity Interval Training
OT  - Oxidative Stress
OT  - Sperm
COIS- The authors declare no conflicts of interest.
EDAT- 2021/03/10 06:00
MHDA- 2021/03/10 06:01
PMCR- 2021/04/01
CRDT- 2021/03/09 08:42
PHST- 2020/03/04 00:00 [received]
PHST- 2020/08/31 00:00 [accepted]
PHST- 2021/03/09 08:42 [entrez]
PHST- 2021/03/10 06:00 [pubmed]
PHST- 2021/03/10 06:01 [medline]
PHST- 2021/04/01 00:00 [pmc-release]
AID - 10.22074/IJFS.2020.134593 [doi]
PST - ppublish
SO  - Int J Fertil Steril. 2021 Apr;15(2):141-147. doi: 10.22074/IJFS.2020.134593. Epub 
      2021 Mar 11.