PMID- 33690087
OWN - NLM
STAT- MEDLINE
DCOM- 20210514
LR  - 20210514
IS  - 2211-0356 (Electronic)
IS  - 2211-0348 (Linking)
VI  - 50
DP  - 2021 May
TI  - Psychosocial stress, blood brain barrier and the development of anti 
      N-methyl-D-aspartate receptor (NMDAR) encephalitis.
PG  - 102876
LID - S2211-0348(21)00143-7 [pii]
LID - 10.1016/j.msard.2021.102876 [doi]
AB  - Throughout life, mechanisms such as damage and inflammation can alter the 
      permeability of the blood-brain barrier(BBB). According to some studies, 
      increasing the permeability of the blood-brain barrier can occur in a 
      time-dependent manner following restraint stress. On the other hand, there have 
      been reports of increased N-Methyl-D-Aspartate Receptor (NMDAR) -Ab 
      seroprevalence in chronic stress conditions. The presence of antibody-secreting 
      cells / memory B cells in the intrathecal area of the brain and their 
      redistribution under various environmental stresses, which can be independent of 
      the BBB status, are other points in this area that can emphasize the role of 
      environmental stress in Anti NMDAR encephalitis.
CI  - Copyright (c) 2021. Published by Elsevier B.V.
FAU - Vahabi, Zahra
AU  - Vahabi Z
AD  - Geriatric Department, Ziaeean Hospital, Tehran University of Medical Sciences, 
      Tehran, Iran; Memory and Behavioral Neurology Division, Roozbeh Hospital, Tehran 
      University of Medical Sciences, Tehran, Iran.
FAU - Etesam, Farnaz
AU  - Etesam F
AD  - Psychosomatic Medicine Research Center, Department of Psychiatry, School of 
      Medicine, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, 
      Iran.
FAU - Zandifar, Atefeh
AU  - Zandifar A
AD  - Cardiovascular Research Center, Shahid Rajaei Educational & Medical Center, 
      Alborz University of Medical Sciences, Karaj, Iran; Social Determinants of Health 
      Research Center, Alborz University of Medical Sciences, Karaj, Iran.
FAU - Badrfam, Rahim
AU  - Badrfam R
AD  - Psychosomatic Medicine Research Center, Department of Psychiatry, Tehran 
      University of Medical Sciences, Tehran, Iran; Department of Psychiatry, Roozbeh 
      Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, 
      Iran. Electronic address: rbadrfam@gmail.com.
LA  - eng
PT  - Letter
DEP - 20210303
PL  - Netherlands
TA  - Mult Scler Relat Disord
JT  - Multiple sclerosis and related disorders
JID - 101580247
RN  - 0 (Autoantibodies)
RN  - 0 (Receptors, N-Methyl-D-Aspartate)
SB  - IM
MH  - *Anti-N-Methyl-D-Aspartate Receptor Encephalitis/complications
MH  - Autoantibodies
MH  - Blood-Brain Barrier
MH  - Humans
MH  - Receptors, N-Methyl-D-Aspartate
MH  - Seroepidemiologic Studies
MH  - Stress, Psychological/complications
OTO - NOTNLM
OT  - Anti N-Methyl-D-Aspartate Receptor (NMDAR) Antibodies
OT  - Blood brain barrier
OT  - Intrathecal
OT  - Permeability
OT  - Stress
EDAT- 2021/03/11 06:00
MHDA- 2021/05/15 06:00
CRDT- 2021/03/10 17:55
PHST- 2020/12/21 00:00 [received]
PHST- 2021/02/21 00:00 [revised]
PHST- 2021/02/28 00:00 [accepted]
PHST- 2021/03/11 06:00 [pubmed]
PHST- 2021/05/15 06:00 [medline]
PHST- 2021/03/10 17:55 [entrez]
AID - S2211-0348(21)00143-7 [pii]
AID - 10.1016/j.msard.2021.102876 [doi]
PST - ppublish
SO  - Mult Scler Relat Disord. 2021 May;50:102876. doi: 10.1016/j.msard.2021.102876. 
      Epub 2021 Mar 3.