PMID- 33693104
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210312
IS  - 2434-0790 (Electronic)
IS  - 2434-0790 (Linking)
VI  - 1
IP  - 12
DP  - 2019 Nov 22
TI  - Construction of a Heart Failure Database Collating Administrative Claims Data and 
      Electronic Medical Record Data to Evaluate Risk Factors for In-Hospital Death and 
      Prolonged Hospitalization.
PG  - 582-592
LID - 10.1253/circrep.CR-19-0051 [doi]
AB  - Background: Clinical studies on heart failure (HF) using diagnosis procedure 
      combination (DPC) databases have attracted attention recently, but data obtained 
      from such databases may lack important information essential for determining the 
      severity of HF. Methods and Results: Using a HF database that collates DPC data 
      and electronic medical records from 3 hospitals in Japan, we investigated factors 
      contributing to prolonged hospitalization and in-hospital death, based on 
      clinical characteristics and data obtained early during hospitalization in 2,750 
      Japanese patients with HF hospitalized between 2011 and 2015. Mean age was 
      77.0+/-13.0 years; 55.3% (n=1,520) were men, and 39.1% (n=759) had left ventricular 
      ejection fraction <40%. In-hospital mortality was 6.0% (n=164) and mean length of 
      stay for patients who were discharged alive was 18.2+/-13.7 days (median, 15 days). 
      Factors contributing to in-hospital death were advanced age, higher New York 
      Heart Association (NYHA) class, low albumin and sodium, and high creatinine and 
      C-reactive protein (CRP). Factors contributing to prolonged hospitalization were 
      higher NYHA class, low Barthel index, low albumin, and high B-type natriuretic 
      peptide, lactate dehydrogenase, and CRP. Conclusions: We have constructed a 
      database of HF hospitalized patients in acute care hospitals in Japan. This 
      approach may be helpful to address clinical parameters of HF patients in any 
      acute care hospital in Japan.
CI  - Copyright (c) 2019, THE JAPANESE CIRCULATION SOCIETY.
FAU - Kodama, Kazuhisa
AU  - Kodama K
AD  - Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center 
      Kumamoto Japan.
FAU - Sakamoto, Tomohiro
AU  - Sakamoto T
AD  - Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center 
      Kumamoto Japan.
FAU - Kubota, Toru
AU  - Kubota T
AD  - Division of Cardiology, Saiseikai Fukuoka General Hospital Fukuoka Japan.
FAU - Takimura, Hideyuki
AU  - Takimura H
AD  - Division of Cardiology, Saiseikai Yokohama Tobu Hospital Kanagawa Japan.
FAU - Hongo, Hiroshi
AU  - Hongo H
AD  - Division of Cardiology, Saiseikai Fukuoka General Hospital Fukuoka Japan.
FAU - Chikashima, Hiromichi
AU  - Chikashima H
AD  - Division of Medical Affairs, Otsuka Pharmaceutical Co., Ltd Tokyo Japan.
FAU - Shibasaki, Yoshiyuki
AU  - Shibasaki Y
AD  - Division of Medical Affairs, Otsuka Pharmaceutical Co., Ltd Tokyo Japan.
FAU - Yada, Toru
AU  - Yada T
AD  - Statistical Analysis Department 1, EPS Corporation Tokyo Japan.
FAU - Node, Koichi
AU  - Node K
AD  - Department of Cardiovascular Medicine, Saga University Saga Japan.
FAU - Nakayama, Takeo
AU  - Nakayama T
AD  - Department of Health Informatics Kyoto University School of Public Health Kyoto 
      Japan.
FAU - Nakao, Koichi
AU  - Nakao K
AD  - Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center 
      Kumamoto Japan.
LA  - eng
PT  - Journal Article
DEP - 20191122
PL  - Japan
TA  - Circ Rep
JT  - Circulation reports
JID - 101746642
PMC - PMC7897689
OTO - NOTNLM
OT  - Acute care hospital
OT  - Diagnosis procedure combination
OT  - Echocardiography
OT  - Heart failure
OT  - Real-world data
COIS- H.T. has received grants and personal fees from Otsuka Pharmaceutical Co., Ltd. 
      The remaining authors declare no conflicts of interest. EPS Corporation was 
      entrusted with the analyses of this study by Otsuka Pharmaceutical Co., Ltd. 
      Construction of the database was funded by Otsuka Pharmaceutical Co., Ltd. From 
      the start of data collection until database fixing, in accordance with protocol, 
      Otsuka Pharmaceutical Co., Ltd employees were not permitted to join discussions 
      regarding the analysis method, selection of variables in the database, outlier 
      criteria, or confirmation of the extraction criteria.
EDAT- 2019/11/22 00:00
MHDA- 2019/11/22 00:01
PMCR- 2019/11/22
CRDT- 2021/03/11 06:39
PHST- 2021/03/11 06:39 [entrez]
PHST- 2019/11/22 00:00 [pubmed]
PHST- 2019/11/22 00:01 [medline]
PHST- 2019/11/22 00:00 [pmc-release]
AID - 10.1253/circrep.CR-19-0051 [doi]
PST - epublish
SO  - Circ Rep. 2019 Nov 22;1(12):582-592. doi: 10.1253/circrep.CR-19-0051.