PMID- 33706689
OWN - NLM
STAT- MEDLINE
DCOM- 20210315
LR  - 20210315
IS  - 0022-9040 (Print)
IS  - 0022-9040 (Linking)
VI  - 61
IP  - 1
DP  - 2021 Feb 10
TI  - An early echocardiographic prediction for functional myocardial recovery after ST 
      elevation myocardial infarction.
PG  - 66-71
LID - 10.18087/cardio.2021.1.n1477 [doi]
AB  - Goals Discrimination of the time course of functional recovery in early period 
      following ST elevation myocardial infarction (STEMI) has prognostic importance. 
      This study aims to establish the ability of the combined systolic-diastolic index 
      (E / (Ea x Sa), for differentiating recoverable myocardium or persistent 
      non-viability in subjects with STEMI.Material and methods 77 patients with first 
      acute STEMI were enrolled to the study. Serial transthoracic echocardiography 
      (TTE) examinations were performed at the time of the admission (immediately after 
      reperfusion), hospital discharge (5+/-1 days) and control examination (30+/-2 days). 
      To assess the association between E / (EaxSa) index and myocardial recovery, two 
      categories (Transient stunning and persistent non-viability) were defined on 
      basis of improvement of left ventricle ejection fraction (LV EF) (Improvement was 
      defined as an increase more than 10 % in LV EF at day 30 compared to 
      baseline).Results 55 patients (71.4 %) had improvement of LV EF and 24 patients 
      (28.6 %) had no recovery of systolic function (30 days LV EF 48.78+/-6.1 vs. 
      39.31+/-8.1 %, p=0.01). The E / (EaxSa) index were significantly higher in the 
      "non-viability" than in stunning group on predischarge and 1 month (1.61+/-0.64 vs 
      1.25+/-0.43, p=0.01 and 1.33+/-0.25 vs 1.14+/-0.21, p=0.01, respectively). The change 
      in the E / (EaxSa) index in early period (within 5+/-1 days) was higher in the 
      stunning group (26 %) compared to non-viability group (15 %) (p=0.033). 
      E / (EaxSa) index was found to be a significant predictor of myocardial recovery 
      in multivariable logistic regression (OR 0.91, 95 % CI 0.83-0.98, p=0.001). Roc 
      curve showed that the cutoff value of E / (EaxSa) index is 1.29 with 73 % of 
      sensitivity and 61 % of specificity (AUC: 0.71, p=0.01, CI: 
      0.54-0.89).Conclusions Our findings suggest that E / (EaxSa) index is a strong 
      predictor of functional recovery; the odds of recovery decreases as E / (EaxSa) 
      index value increases.
FAU - Karakus, Alper
AU  - Karakus A
AD  - Department of Cardiology, Besni State Hospital, Adiyaman, Turkey.
FAU - Uguz, Berat
AU  - Uguz B
AD  - Department of Cardiology, Bursa City Hospital, Bursa, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20210210
PL  - Russia (Federation)
TA  - Kardiologiia
JT  - Kardiologiia
JID - 0376351
SB  - IM
MH  - Diastole
MH  - Echocardiography
MH  - Humans
MH  - Myocardium
MH  - Predictive Value of Tests
MH  - *ST Elevation Myocardial Infarction/diagnosis
MH  - Ventricular Function, Left
EDAT- 2021/03/13 06:00
MHDA- 2021/03/16 06:00
CRDT- 2021/03/12 05:45
PHST- 2020/11/28 00:00 [received]
PHST- 2021/01/08 00:00 [accepted]
PHST- 2021/01/04 00:00 [revised]
PHST- 2021/03/12 05:45 [entrez]
PHST- 2021/03/13 06:00 [pubmed]
PHST- 2021/03/16 06:00 [medline]
AID - 10.18087/cardio.2021.1.n1477 [doi]
PST - epublish
SO  - Kardiologiia. 2021 Feb 10;61(1):66-71. doi: 10.18087/cardio.2021.1.n1477.