PMID- 33708567
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210313
IS  - 2227-684X (Print)
IS  - 2227-8575 (Electronic)
IS  - 2227-684X (Linking)
VI  - 10
IP  - 2
DP  - 2021 Feb
TI  - Resecting a solitary cervical vagal nerve neurofibroma via endoscopic surgery: a 
      case report.
PG  - 844-851
LID - 10.21037/gs-20-706 [doi]
AB  - Neurofibromas predominately consist of Schwann cells and fibroblasts, which 
      mainly originate from neurofibromatosis type 1. However, solitary cervical vagal 
      nerve neurofibroma (VNN) has rarely been reported in previously published 
      literature. Additionally, the onset of VNN is characteristically chronic, 
      asymptomatic, and insidious, and is often discovered unexpectedly through 
      physical examination or imaging. The exact etiology and pathogenesis of VNN are 
      yet to be clarified and need further exploration. Consequently, the definitive 
      diagnosis of VNN mainly depends on pathological and immunohistochemical 
      examinations. Immunohistochemically, tumor cells are positive for transcription 
      factor S-100, SRY-related HMG-box (SOX)-10, and vascular marker CD34 will 
      contribute to the diagnosis of VNN. In this uncommon case of left cervical VNN, 
      the patient received comprehensive radiological evaluation before the operation 
      and then underwent mass resection through endoscopic surgery via an axillary and 
      chest wall approach. The patient was satisfied with the postoperative appearance 
      of the neck. Besides, no postoperative complications or recurrence were observed 
      during the consecutive six-month follow-up. Therefore, the successful application 
      of total endoscopic surgery via the bilateral axilla-breast approach (BABA) on 
      this case of neurogenic tumor presents new insights into expanding the operative 
      indications of this technique, which could be a rational candidate for this kind 
      of neck tumor with the requirements of satisfactory aesthetic appearance.
CI  - 2021 Gland Surgery. All rights reserved.
FAU - Luo, Haojun
AU  - Luo H
AD  - Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China.
FAU - Min, Yu
AU  - Min Y
AD  - Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China.
FAU - Zeng, Bin
AU  - Zeng B
AD  - Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China.
FAU - Feng, Yang
AU  - Feng Y
AD  - Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China.
FAU - Yin, Guobing
AU  - Yin G
AD  - Department of Breast and Thyroid Surgery, The Second Affiliated Hospital of 
      Chongqing Medical University, Chongqing, China.
LA  - eng
PT  - Case Reports
PL  - China (Republic : 1949- )
TA  - Gland Surg
JT  - Gland surgery
JID - 101606638
PMC - PMC7944062
OTO - NOTNLM
OT  - Neurofibroma
OT  - endoscopic surgery
OT  - surgery
OT  - thyroid
OT  - vagal nerve
COIS- Conflicts of Interest: All authors have completed the ICMJE uniform disclosure 
      form (available at http://dx.doi.org/10.21037/gs-20-706). The authors have no 
      conflicts of interest to declare.
EDAT- 2021/03/13 06:00
MHDA- 2021/03/13 06:01
PMCR- 2021/02/01
CRDT- 2021/03/12 07:18
PHST- 2021/03/12 07:18 [entrez]
PHST- 2021/03/13 06:00 [pubmed]
PHST- 2021/03/13 06:01 [medline]
PHST- 2021/02/01 00:00 [pmc-release]
AID - gs-10-02-844 [pii]
AID - 10.21037/gs-20-706 [doi]
PST - ppublish
SO  - Gland Surg. 2021 Feb;10(2):844-851. doi: 10.21037/gs-20-706.