PMID- 33721062
OWN - NLM
STAT- MEDLINE
DCOM- 20220210
LR  - 20220210
IS  - 1433-8726 (Electronic)
IS  - 0724-4983 (Linking)
VI  - 39
IP  - 9
DP  - 2021 Sep
TI  - Recent evidence for anatomic endoscopic enucleation of the prostate (AEEP) in 
      patients with benign prostatic obstruction on antiplatelet or anticoagulant 
      therapy.
PG  - 3187-3196
LID - 10.1007/s00345-021-03647-z [doi]
AB  - INTRODUCTION: Due to demographic changes in today's society, the number of 
      patients with lower urinary tract symptoms (LUTS) due to benign prostatic 
      hyperplasia (BPH) is increasing. Similarly, the proportion of patients with 
      cardiovascular risk factors undergoing antiplatelet (AP) or anticoagulation (AC) 
      therapy is growing as well. METHODS: This review discusses the current literature 
      on various techniques used for anatomic endoscopic enucleation of the prostate 
      (AEEP) in patients on AC/AP therapy. RESULTS: The large number of energy sources 
      used for AEEP makes it difficult to compare them. Overall, fewer 
      bleeding-associated complications arise in patients under AP compared to AC or 
      bridging therapy with low molecular weight heparin. However, perioperatively both 
      AP and AC therapy lead to a higher risk of bleeding complications compared to 
      patients not taking anticoagulants. CONCLUSIONS: The literature shows that AEEP 
      is possible and efficacious in patients under AC/AP therapy, with only slight 
      differences compared to patients not taking AC/AP drugs, on a short and long-term 
      basis. Nevertheless, the sparse data, the retrospective nature of many studies 
      and the inclusion of prostate sizes between 50 and 110 ml only, make it difficult 
      to come to strong conclusions.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Netsch, C
AU  - Netsch C
AUID- ORCID: 0000-0001-5685-0731
AD  - Department of Urology, Asklepios Hospital Barmbek, Rubenkamp 220, 22291, Hamburg, 
      Germany. c.netsch@asklepios.com.
FAU - Herrmann, T R W
AU  - Herrmann TRW
AD  - Department of Urology, Urologische Klinik Spital Thurgau, Kantonsspital 
      Frauenfeld, Frauenfeld, Switzerland.
FAU - Bozzini, G
AU  - Bozzini G
AD  - Department of Urology, ASST Valle Olona, Ospedale Di Busto Arsizio (VA), Busto 
      Arsizio, Italy.
FAU - Berti, L
AU  - Berti L
AD  - Department of Urology, ASST Valle Olona, Ospedale Di Busto Arsizio (VA), Busto 
      Arsizio, Italy.
FAU - Gross, A J
AU  - Gross AJ
AD  - Department of Urology, Asklepios Hospital Barmbek, Rubenkamp 220, 22291, Hamburg, 
      Germany.
FAU - Becker, B
AU  - Becker B
AD  - Department of Urology, Asklepios Hospital Barmbek, Rubenkamp 220, 22291, Hamburg, 
      Germany.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20210315
PL  - Germany
TA  - World J Urol
JT  - World journal of urology
JID - 8307716
RN  - 0 (Anticoagulants)
RN  - 0 (Platelet Aggregation Inhibitors)
SB  - IM
MH  - Anticoagulants/*therapeutic use
MH  - *Endoscopy
MH  - Humans
MH  - Male
MH  - Platelet Aggregation Inhibitors/*therapeutic use
MH  - Prostatectomy/*methods
MH  - Prostatic Hyperplasia/*surgery
OTO - NOTNLM
OT  - BPO
OT  - Benign prostatic obstruction
OT  - Enucleation
OT  - Oral anticoagulation
OT  - Transurethral enucleation
EDAT- 2021/03/16 06:00
MHDA- 2022/02/11 06:00
CRDT- 2021/03/15 17:30
PHST- 2020/12/21 00:00 [received]
PHST- 2021/02/19 00:00 [accepted]
PHST- 2021/03/16 06:00 [pubmed]
PHST- 2022/02/11 06:00 [medline]
PHST- 2021/03/15 17:30 [entrez]
AID - 10.1007/s00345-021-03647-z [pii]
AID - 10.1007/s00345-021-03647-z [doi]
PST - ppublish
SO  - World J Urol. 2021 Sep;39(9):3187-3196. doi: 10.1007/s00345-021-03647-z. Epub 
      2021 Mar 15.